Patents by Inventor Alon M. Chen

Alon M. Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of increasing insulin sensitivity or decreasing insulin secretion by administering corticotropin releasing factor receptor-2 inhibitors
    Patent number: 7815905
    Abstract: In some aspects, the invention relates to methods for increasing insulin-sensitivity and/or decreasing insulin secretion in an individual by reducing or inhibiting corticotropin releasing factor 2 (CRFR2) signaling. CRFR2 antagonists may block agonism by one or more CRFR2 agonist, for example Ucn 2 or Ucn 3. Methods according to the invention may be use to treat a variety of metabolic diseases such as type 2 diabetes, metabolic syndrome, nonalcoholic fatty liver disease, polycystic ovarian syndrome and obesity.
    Type: Grant
    Filed: January 29, 2007
    Date of Patent: October 19, 2010
    Assignee: Research Development Foundation
    Inventors: Alon M. Chen, Kuo-Fen Lee, Chien Li, Wylie W. Vale
  • CORTICOTROPIN RELEASING FACTOR RECEPTOR-2 INHIBITORS AND USES THEREOF
    Publication number: 20080161235
    Abstract: In some aspects, the invention relates to methods for increasing insulin-sensitivity and/or decreasing insulin secretion in an individual by reducing or inhibiting corticotropin releasing factor 2 (CRFR2) signaling. CRFR2 antagonists may block agonism by one or more CRFR2 agonist, for example Ucn 2 or Ucn 3. Methods according to the invention may be use to treat a variety of metabolic diseases such as type 2 diabetes, metabolic syndrome, nonalcoholic fatty liver disease, polycystic ovarian syndrome and obesity.
    Type: Application
    Filed: January 29, 2007
    Publication date: July 3, 2008
    Inventors: Alon M. Chen, Kuo-Fen Lee, Chien Li, Wylie W. Vale