Abstract: An Integrated Circuit (IC) includes one or more functional hardware circuits, one or more processor cores, a cause-tree circuit, a memory buffer, and an analysis circuit. The processor cores are to handle events occurring in the functional hardware circuits. The cause-tree circuit includes leaf nodes, middle nodes and a root node. The leaf nodes are to collect the events from the one or more functional hardware circuits. The middle nodes are to coalesce the collected events and to deliver the events to the root node. The memory buffer is to buffer a plurality of the events delivered to the root node, so as to trigger the processor cores to handle the buffered events. The buffer analysis circuit is to analyze a performance of the cause-tree circuit based on the events buffered in the memory buffer.

Abstract: Fluidic devices and related methods are generally provided. The fluidic devices described herein may be useful, for example, for diagnostic purposes (e.g., detection of the presence of one or more disease causing bacteria in a patient sample). Unlike certain existing fluidic devices for diagnostic purposes, the fluidic devices and methods described herein may be useful for detecting the presence of numerous disease causing bacteria in a patient sample substantially simultaneously (e.g., in parallel). In some embodiments, the fluidic devices and methods described herein provide highly sensitive detection of microbes in relatively large fluidic samples (e.g., between 0.5 mL and about 5 mL), as compared to certain existing fluidic detection (e.g., microfluidic) devices and methods. In an exemplary embodiment, increased detection sensitivity of microbial pathogens present in a patient sample (e.g., blood) is performed by selectively removing human nucleic acid prior to sensitive detection of microbial infection.

Abstract: An Integrated Circuit (IC) includes one or more functional hardware circuits, one or more processor cores, a cause-tree circuit, a memory buffer, and an analysis circuit. The processor cores are to handle events occurring in the functional hardware circuits. The cause-tree circuit includes leaf nodes, middle nodes and a root node. The leaf nodes are to collect the events from the one or more functional hardware circuits. The middle nodes are to coalesce the collected events and to deliver the events to the root node. The memory buffer is to buffer a plurality of the events delivered to the root node, so as to trigger the processor cores to handle the buffered events. The buffer analysis circuit is to analyze a performance of the cause-tree circuit based on the events buffered in the memory buffer.

Abstract: An apparatus includes an input interface to receive incoming packets from a first network device and an output interface to send outgoing packets to a second network device. Media access control security (MACsec) circuitry is coupled between the input interface and the output interface. Bypass flow-control (FC) circuitry is coupled between the input interface and the MACsec circuitry. The bypass FC circuitry is to detect an FC packet in the incoming packets and pass the FC packet passively to the output interface to enable end-to-end flow control directly between the first network device and the second network device.

Abstract: The present disclosure generally relates to the field of microbial pathogen detection and identification utilizing genomic sequence recognition.

Abstract: The present disclosure generally relates to the field of ultrasensitive microbial pathogen detection and identification utilizing genomic sequence recognition.

Abstract: A System-On-Chip (SoC) includes a set of registers, a processor, and Out-Of-Order Write (OOOW) circuitry. The processor is to execute instructions including write instructions. After issuing a first write instruction to any of the registers in the set, the processor is to await an acknowledgement for the first write instruction before issuing a second write instruction to any of the registers in the set. The OOOW circuitry is to identify the write instructions issued by the processor to the registers in the set, to perform the identified write instructions in the registers irrespective of acknowledgements from the registers, and to send to the processor imitated acknowledgements for the identified write instructions.

Abstract: The present disclosure generally relates to the field of microbial pathogen detection and identification utilizing genomic sequence recognition.

Abstract: A System-On-Chip (SoC) includes a set of registers, a processor, and Out-Of-Order Write (OOOW) circuitry. The processor is to execute instructions including write instructions. After issuing a first write instruction to any of the registers in the set, the processor is to await an acknowledgement for the first write instruction before issuing a second write instruction to any of the registers in the set. The OOOW circuitry is to identify the write instructions issued by the processor to the registers in the set, to perform the identified write instructions in the registers irrespective of acknowledgements from the registers, and to send to the processor imitated acknowledgements for the identified write instructions.

Abstract: An apparatus includes a processor and split-read control circuitry (SRCC). The processor is to issue a set of one or more split-read requests for loading one or more data values to one or more respective local registers of the processor. The SRCC is to receive the set of one or more split-read requests, to read the one or more data values on behalf of the processor, and to write the data values into the one or more respective local registers. The processor and the SRCC are to coordinate a status of the split-read requests via a split-read-status indication.

Abstract: The present disclosure generally relates to the field of ultrasensitive microbial pathogen detection and identification utilizing genomic sequence recognition.

Abstract: Methods and devices for isolating microbial cells from a sample, extracting eukaryotic DNA from a sample, and identifying the microbial species in the sample are disclosed herein.

Abstract: Fluidic systems and reagent carriers suitable for storing reagents in a desirable manner are generally provided. In some embodiments, a reagent carrier stores a liquid film comprising a solid reagent and/or stores different reagents in different locations. In some embodiments, a fluidic system comprises a reagent carrier constrained such that it comprises an elongated axis positioned within 30° of a vertical axis of the fluidic reservoir.

Abstract: Fluidic systems and reagent carriers suitable for storing reagents in a desirable manner are generally provided. In some embodiments, a reagent carrier stores a liquid film comprising a solid reagent and/or stores different reagents in different locations. In some embodiments, a fluidic system comprises a reagent carrier constrained such that it comprises an elongated axis positioned within 30° of a vertical axis of the fluidic reservoir.

Abstract: An apparatus includes a processor and split-read control circuitry (SRCC). The processor is to issue a set of one or more split-read requests for loading one or more data values to one or more respective local registers of the processor. The SRCC is to receive the set of one or more split-read requests, to read the one or more data values on behalf of the processor, and to write the data values into the one or more respective local registers. The processor and the SRCC are to coordinate a status of the split-read requests via a split-read-status indication.

Abstract: An apparatus includes an input interface to receive incoming packets from a first network device and an output interface to send outgoing packets to a second network device. Media access control security (MACsec) circuitry is coupled between the input interface and the output interface. Bypass flow-control (FC) circuitry is coupled between the input interface and the MACsec circuitry. The bypass FC circuitry is to detect an FC packet in the incoming packets and pass the FC packet passively to the output interface to enable end-to-end flow control directly between the first network device and the second network device.

Abstract: Methods and devices for isolating microbial cells from a sample, extracting eukaryotic DNA from a sample, and identifying the microbial species in the sample are disclosed herein.

Abstract: The present disclosure provides for compositions of ?PNA probes. Additionally, the present disclosure provide for methods and kits using ?PNA probes for the diagnosis of sepsis.

Abstract: Fluidic systems and reagent carriers suitable for storing reagents in a desirable manner are generally provided. In some embodiments, a reagent carrier stores a liquid film comprising a solid reagent and/or stores different reagents in different locations. In some embodiments, a fluidic system comprises a reagent carrier constrained such that it comprises an elongated axis positioned within 30° of a vertical axis of the fluidic reservoir.

Abstract: The present disclosure provides for compositions of ?PNA probes. Additionally, the present disclosure provide for methods and kits using ?PNA probes for the diagnosis of sepsis.