Abstract: Supplying therapeutic gas with improved mouth sensing. At least one example is a system and related method of treating CPAP non-compliance by delivery of therapeutic gas during and after sleep apnea events. Another example is a system and related method to change the volume of therapeutic gas delivered responsive to changes in oral resistance to the airflow associated with the transitions from wakefulness to sleep. Yet still other examples are systems and related methods of selective delivery of the therapeutic gas in which the left and right sides of the mouth are measured and delivered to independently to take into account respiratory airflow may not be evenly distributed across the mouth.

Abstract: Sensing airflow and delivering therapeutic gas to a patient. At least some of the example embodiments are methods including: titrating a patient with therapeutic gas during a period of time when a flow state of breathing orifices is in a first state, the titrating results in a prescription titration volume; and then delivering the prescription titration volume of therapeutic gas to the patient when the flow state of the breathing orifices is in a second state different than the first state, the delivering only to the breathing orifices open to flow.

Abstract: Supplying therapeutic gas. At least one example is a method of providing therapeutic gas to a patient, the method comprising: sensing a signal indicative of an exhalation airflow from the patient, the exhalation airflow is non-zero and an airflow rate trending toward zero; sensing, during the exhalation airflow, a change in the airflow rate prior to a contiguous inhalation; and delivering a bolus of therapeutic gas to the proximal end of nasal cannula responsive to the change in the airflow rate.

Abstract: Supplying therapeutic gas based on inhalation duration. At least some of the example embodiments are methods including: sensing a current inhalation of the patient; providing a flow of therapeutic gas to the patient based on the sensing; and ceasing the flow of therapeutic gas to the patient based on a value indicative of previous inhalation duration.

Abstract: Sensing airflow and delivering therapeutic gas to a patient. At least one example embodiment is a method including: sensing, by a delivery device, that multiple breathing orifices are open to flow; and during a plurality of subsequent inhalations in which multiple breathing orifices are open to flow; and delivering, by the delivery device, a bolus of therapeutic gas to only one breathing orifice during each inhalation, and alternating delivery location in subsequent inhalations. The example delivering may further comprise: supplying therapeutic gas only from an accumulator during a first portion each inhalation; dispensing therapeutic gas from the accumulator and from a pressure regulator during a second portion of each inhalation, the second portion immediately subsequent to the first portion.

Abstract: At least one example embodiment is a method of generating a capnographic waveform, the method including: measuring carbon dioxide in exhaled gas flowing in a first flow path, the measuring creates a first set of values indicative of carbon dioxide; measuring, by the controller of the device, carbon dioxide in exhaled gas flowing in a second flow path distinct from the first flow path, the measuring creates a second set of values indicative of carbon dioxide; and creating, by the controller of the device, a capnographic waveform. Creating the capnographic waveform may including using the first set of values indicative of carbon dioxide, the second set of values indicative of carbon dioxide, and/or both the first and second sets of values of carbon dioxide.

Abstract: A dynamic oxygen conserver includes a housing and an inhalation sensor coupled to the housing. The sensor has a printed circuit board (PCB) assembly with a first PCB for a breathing side for a user of the dynamic oxygen conserver. A second PCB is coupled to the first PCB. The second PCB is for an atmosphere side opposite the breathing side. In addition, a spacer assembly is coupled between the first and second PCB. The spacer assembly has a metallized diaphragm this is dynamically responsive to breathing by the user of the dynamic oxygen conserver.

Abstract: Sensing airflow and delivering therapeutic gas to a patient. At least some of the example embodiments are methods including: titrating a patient with therapeutic gas during a period of time when a flow state of breathing orifices is in a first state, the titrating results in a prescription titration volume; and then delivering the prescription titration volume of therapeutic gas to the patient when the flow state of the breathing orifices is in a second state different than the first state, the delivering only to the breathing orifices open to flow.

Abstract: Sensing airflow and delivering therapeutic gas to a patient. At least some of the example embodiments are methods including: titrating a patient with therapeutic gas during a period of time when a flow state of breathing orifices is in a first state, the titrating results in a prescription titration volume; and then delivering the prescription titration volume of therapeutic gas to the patient when the flow state of the breathing orifices is in a second state different than the first state, the delivering only to the breathing orifices open to flow.

Abstract: Sensing airflow and delivering therapeutic gas to a patient. At least some of the example embodiments are methods including: titrating a patient with therapeutic gas during a period of time when a flow state of breathing orifices is in a first state, the titrating results in a prescription titration volume; and then delivering the prescription titration volume of therapeutic gas to the patient when the flow state of the breathing orifices is in a second state different than the first state, the delivering only to the breathing orifices open to flow.

Abstract: Hose connection system for narially sensitive diagnostic devices. At least some of the illustrative embodiments are systems including a test device and a nasal cannula. The test device includes a first port configured to sense an attribute of airflow, and a second port configured to sense an attribute of airflow. The nasal cannula includes a first hose configured to fluidly couple on a device-end to the first port (and the first hose configured to fluidly couple between the first port and a first naris of a patient), and a second hose configured to fluidly couple on a device-end to the second port (and the second hose configured to fluidly couple between the second port and a second naris of the patient). The nasal cannula is configured such that the first hose only couples to the first port and the second hose only couples to the second port.

Abstract: A trans-fill method and system comprising obtaining therapeutic gas from a therapeutic gas source, compressing the therapeutic gas from the therapeutic gas source in at least two stages to create an intermediate therapeutic gas stream and a high pressure therapeutic gas stream, supplying therapeutic gas to a patient from the intermediate therapeutic gas stream, and filling a cylinder with the therapeutic gas from the high pressure therapeutic gas stream substantially simultaneously with supplying therapeutic gas to the patient.

Abstract: Determining nasal resistance. At least some of the illustrative embodiments are methods including: applying negative pressure to a patient's mouth and thereby creating airflow that flows in a first nare and out the patient's mouth; measuring at least one property of the airflow during the causing; and determining an indicia of nasal resistance of the patient, the determining based on the at least one property.

Abstract: Determining the nasal resistance. At least some of the illustrative embodiments are methods including: forcing airflow into a first nare of a patient; measuring at least one property of the airflow during the forcing; and determining an indicia of nasal resistance of the patient, the determining based on the at least one property.

Abstract: A method and system of operating a trans-fill device. At least some of the illustrative embodiments are methods comprising generating an enriched gas stream from atmospheric air, and operating an intensifier which, when provided the enriched gas stream, produces a cylinder fill gas stream. The operating continues in the absence of the enriched gas stream being provided to the intensifier.

Abstract: A trans-fill method and system comprising obtaining therapeutic gas from a therapeutic gas source, compressing the therapeutic gas from the therapeutic gas source in at least two stages to create an intermediate therapeutic gas stream and a high pressure therapeutic gas stream, supplying therapeutic gas to a patient from the intermediate therapeutic gas stream, and filling a cylinder with the therapeutic gas from the high pressure therapeutic gas stream substantially simultaneously with supplying therapeutic gas to the patient.

Abstract: A trans-fill method and system comprising obtaining therapeutic gas from a therapeutic gas source, compressing the therapeutic gas from the therapeutic gas source in at least two stages to create an intermediate therapeutic gas stream and a high pressure therapeutic gas stream, supplying therapeutic gas to a patient from the intermediate therapeutic gas stream, and filling a cylinder with the therapeutic gas from the high pressure therapeutic gas stream substantially simultaneously with supplying therapeutic gas to the patient.

Abstract: A method and system for providing therapeutic gas to a patient during positive airway pressure ventilation and, more particularly, detecting the presence of a mouth leak during ventilation and, upon the detection of a mouth leak, reducing the applied pressure so as to reduce irritation and discomfort experienced by the patient. Respiratory air flow from a patient is measured in a waveform as a function of time. An approximate value of the root mean square voltage of the waveform is established during a period in which the patient is experiencing a mouth leak and a root mean square voltage of the waveform is established during a period in which the patient is experiencing an apneic event. The waveform is subsequently monitored and the rate of respiratory airflow is decreased when there is an indication of a mouth leak provided there is no indication of an apneic event.

Abstract: A method and related system of filling therapeutic gas cylinders. At least some of the illustrative embodiments are a method comprising determining, by a cylinder fill device, a rated pressure of a therapeutic gas cylinder, and filling the cylinder with the cylinder fill device substantially to the rated pressure.

Abstract: A method and system of coordinating an intensifier and sieve beds. At least some of the illustrative embodiments are methods comprising coordinating control of an intensifier with cycles of a sieve bed fluidly coupled to the intensifier such that there is at least one low pressure stroke of the intensifier and at least one high pressure stroke of the intensifier during a fill cycle of the sieve bed.