Abstract: The biological transport and storage device includes a cooling chamber containing one or more biological samples in a sample holder surrounded by coolant air which is intermittently circulated through the cooling chamber across a thermoelectric unit that can cool or heat the circulating air. A fan is used to circulate air through the cooling chamber, and a separate fan may be used to introduce and circulate ambient air over the thermoelectric unit in incoming air chamber. A sample rotator motor may be used to rotate the samples within the cooling chamber. A control system includes a PLC controller that receives temperature inputs from the sample holder, ambient air within the cooling chamber, and the thermoelectric unit, as well as possibly within the sample. The PLC receives these temperature inputs, and controls the fans, sample rotator motor, and thermoelectric units such that the temperature of the samples within the cooling chamber are cooled at a predetermined and selectable temperature profile.