Patents by Inventor Alvaro J. Laguna

Alvaro J. Laguna has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230381466
    Abstract: Systems and method for using a sleeve for enhanced drug delivery are described. The sleeve may incorporate porous materials and may be coated or treated with various drugs and/or therapeutic agents. The sleeve may be utilized in cooperation with balloon catheters and/or other devices. When acting as a reservoir for holding various drugs and/or therapeutic agents, the drug delivery sleeve provides a means of reducing drug losses as well as a controlled mechanism for drug release. The materials for the sleeve, constructed by various techniques, may be circumferentially distensible, may be elastic, and may have varying degrees of recoil as needed for any particular purpose.
    Type: Application
    Filed: August 10, 2023
    Publication date: November 30, 2023
    Inventor: Alvaro J. Laguna
  • Publication number: 20220072282
    Abstract: Systems and method for using a sleeve for enhanced drug delivery are described. The sleeve may incorporate porous materials and may be coated or treated with various drugs and/or therapeutic agents. The sleeve may be utilized in cooperation with balloon catheters and/or other devices. When acting as a reservoir for holding various drugs and/or therapeutic agents, the drug delivery sleeve provides a means of reducing drug losses as well as a controlled mechanism for drug release. The materials for the sleeve, constructed by various techniques, may be circumferentially distensible, may be elastic, and may have varying degrees of recoil as needed for any particular purpose.
    Type: Application
    Filed: November 17, 2021
    Publication date: March 10, 2022
    Inventor: Alvaro J. Laguna
  • Patent number: 11191929
    Abstract: Systems and method for using a sleeve for enhanced drug delivery are described. The sleeve may incorporate porous materials and may be coated or treated with various drugs and/or therapeutic agents. The sleeve may be utilized in cooperation with balloon catheters and/or other devices. When acting as a reservoir for holding various drugs and/or therapeutic agents, the drug delivery sleeve provides a means of reducing drug losses as well as a controlled mechanism for drug release. The materials for the sleeve, constructed by various techniques, may be circumferentially distensible, may be elastic, and may have varying degrees of recoil as needed for any particular purpose.
    Type: Grant
    Filed: March 22, 2019
    Date of Patent: December 7, 2021
    Assignee: Sentient Holdings, LLC
    Inventor: Alvaro J. Laguna
  • Publication number: 20190282790
    Abstract: Systems and method for using a sleeve for enhanced drug delivery are described. The sleeve may incorporate porous materials and may be coated or treated with various drugs and/or therapeutic agents. The sleeve may be utilized in cooperation with balloon catheters and/or other devices. When acting as a reservoir for holding various drugs and/or therapeutic agents, the drug delivery sleeve provides a means of reducing drug losses as well as a controlled mechanism for drug release. The materials for the sleeve, constructed by various techniques, may be circumferentially distensible, may be elastic, and may have varying degrees of recoil as needed for any particular purpose.
    Type: Application
    Filed: March 22, 2019
    Publication date: September 19, 2019
    Inventor: Alvaro J. Laguna
  • Patent number: 10293144
    Abstract: Systems and method for using a sleeve for enhanced drug delivery are described. The sleeve may incorporate porous materials and may be coated or treated with various drugs and/or therapeutic agents. The sleeve may be utilized in cooperation with balloon catheters and/or other devices. When acting as a reservoir for holding various drugs and/or therapeutic agents, the drug delivery sleeve provides a means of reducing drug losses as well as a controlled mechanism for drug release. The materials for the sleeve, constructed by various techniques, may be circumferentially distensible, may be elastic, and may have varying degrees of recoil as needed for any particular purpose.
    Type: Grant
    Filed: November 15, 2016
    Date of Patent: May 21, 2019
    Assignee: Sentinent Holdings, LLC
    Inventor: Alvaro J. Laguna
  • Publication number: 20170360584
    Abstract: The present invention provides apparatus and methods for a conduit, such as an implantable conduit for a vessel. The conduit may comprise a main member and a side-branch member. The conduit may be implanted with the side-branch member initially disposed within the main member. When positioned, the side-branch member may then be extended from within the main member and into a vessel side-branch. The materials for the conduit may include circumferentially distensible and/or low recoil materials. The materials for the conduit may be constructed by various techniques and may include materials with enhanced flexibility and kink resistance.
    Type: Application
    Filed: August 7, 2017
    Publication date: December 21, 2017
    Inventor: Alvaro J. Laguna
  • Patent number: 9763811
    Abstract: The present invention provides apparatus and methods for a conduit, such as an implantable conduit for a vessel. The conduit may comprise a main member and a side-branch member. The conduit may be implanted with the side-branch member initially disposed within the main member. When positioned, the side-branch member may then be extended from within the main member and into a vessel side-branch. The materials for the conduit may include circumferentially distensible and/or low recoil materials. The materials for the conduit may be constructed by various techniques and may include materials with enhanced flexibility and kink resistance.
    Type: Grant
    Filed: August 19, 2014
    Date of Patent: September 19, 2017
    Assignee: DSM IP Assets BV
    Inventor: Alvaro J. Laguna
  • Publication number: 20170151420
    Abstract: Systems and method for using a sleeve for enhanced drug delivery are described. The sleeve may incorporate porous materials and may be coated or treated with various drugs and/or therapeutic agents. The sleeve may be utilized in cooperation with balloon catheters and/or other devices. When acting as a reservoir for holding various drugs and/or therapeutic agents, the drug delivery sleeve provides a means of reducing drug losses as well as a controlled mechanism for drug release. The materials for the sleeve, constructed by various techniques, may be circumferentially distensible, may be elastic, and may have varying degrees of recoil as needed for any particular purpose.
    Type: Application
    Filed: November 15, 2016
    Publication date: June 1, 2017
    Inventor: Alvaro J. Laguna
  • Patent number: 9549831
    Abstract: The present invention provides apparatus and methods for a conduit, such as an implantable conduit for a vessel. The conduit may comprise a main member and a side branch member. The conduit may be implanted with the side-branch member initially disposed within the main member. When positioned, the side-branch member may then be extended from within the main member and into a vessel side-branch, The materials for the conduit may include circumferentially distensible and/or low recoil materials.
    Type: Grant
    Filed: August 9, 2005
    Date of Patent: January 24, 2017
    Assignee: DSM IP Assets B.V.
    Inventor: Alvaro J. Laguna
  • Patent number: 9539121
    Abstract: The present invention provides apparatus and methods for a conduit, such as an implantable conduit for a vessel. The conduit may comprise a main member and a side-branch member. The conduit may be implanted with the side-branch member initially disposed within the main member. When positioned, the side-branch member may then be extended from within the main member and into a vessel side-branch. The materials for the conduit may include circumferentially distensible and/or low recoil materials. The materials for the conduit may be constructed by various techniques and may include materials with enhanced flexibility and kink resistance.
    Type: Grant
    Filed: November 22, 2010
    Date of Patent: January 10, 2017
    Assignee: DSM IP Assets B.V.
    Inventor: Alvaro J. Laguna
  • Publication number: 20140352875
    Abstract: The present invention provides apparatus and methods for a conduit, such as an implantable conduit for a vessel. The conduit may comprise a main member and a side-branch member. The conduit may be implanted with the side-branch member initially disposed within the main member. When positioned, the side-branch member may then be extended from within the main member and into a vessel side-branch. The materials for the conduit may include circumferentially distensible and/or low recoil materials. The materials for the conduit may be constructed by various techniques and may include materials with enhanced flexibility and kink resistance.
    Type: Application
    Filed: August 19, 2014
    Publication date: December 4, 2014
    Inventor: Alvaro J. Laguna
  • Patent number: 8808360
    Abstract: The present invention provides apparatus and methods for a conduit, such as an implantable conduit for a vessel. The conduit may comprise a main member and a side-branch member. The conduit may be implanted with the side-branch member initially disposed within the main member. When positioned, the side-branch member may then be extended from within the main member and into a vessel side-branch. The materials for the conduit may include circumferentially distensible and/or low recoil materials. The materials for the conduit may be constructed by various techniques and may include materials with enhanced flexibility and kink resistance.
    Type: Grant
    Filed: January 23, 2013
    Date of Patent: August 19, 2014
    Assignee: DSM IP Assets B.V.
    Inventor: Alvaro J. Laguna
  • Publication number: 20120310326
    Abstract: A tube which circumferentially distends from its initial circumference upon the application of a circumferentially distending force such as applied by an internal pressure, and which exhibits minimal recoil following the removal of the circumferentially distending force. The tube preferably has a second circumference larger than the initial circumference which remains substantially unchanged by further increasing force once it has been achieved. Because of the distensible circumference and minimal recoil of the tube, the tube is useful as a liner for pipes and vessels and particularly for pipes and vessels having irregular internal surfaces to which the tube can smoothly conform. The tube is preferably made from porous PTFE with thin walls, in which form it is particularly useful as a liner for both living and prosthetic blood vessels and to line anastomoses between living and prosthetic blood vessels.
    Type: Application
    Filed: August 20, 2012
    Publication date: December 6, 2012
    Inventors: Carey V. Campbell, Alvaro J. Laguna, James D. Lewis, Mark E. Mayrand, David J. Myers
  • Publication number: 20110066220
    Abstract: The present invention provides apparatus and methods for a conduit, such as an implantable conduit for a vessel. The conduit may comprise a main member and a side-branch member. The conduit may be implanted with the side-branch member initially disposed within the main member. When positioned, the side-branch member may then be extended from within the main member and into a vessel side-branch. The materials for the conduit may include circumferentially distensible and/or low recoil materials. The materials for the conduit may be constructed by various techniques and may include materials with enhanced flexibility and kink resistance.
    Type: Application
    Filed: November 22, 2010
    Publication date: March 17, 2011
    Applicant: SENTIENT ENGINEERING & TECHNOLOGY, L.L.C.
    Inventor: Alvaro J. Laguna
  • Patent number: 7892201
    Abstract: The present invention provides improved methods for forming and mounting a sleeve on a catheter shaft in order to form a distensible balloon catheter. The balloon is formed from a distensible sleeve that is treated to render one or both of its ends essentially non-distensible. The balloon is mounted on the catheter shaft by the non-distensible ends, without compromising the distensible operative portion of the balloon. The balloon may also be mounted using non-distensible tape or similar means to achieve a similar result.
    Type: Grant
    Filed: August 27, 1999
    Date of Patent: February 22, 2011
    Assignee: Gore Enterprise Holdings, Inc.
    Inventors: Alvaro J. Laguna, Carey V. Campbell
  • Publication number: 20080312730
    Abstract: Balloon catheters having the strength and maximum inflated diameter characteristics of an angioplasty balloon and having the recovery characteristics during deflation of an elastic embolectomy balloon. The balloon catheter can be made in very small sizes and has a lubricious and chemically inert outer surface. The balloon catheter is easy to navigate through tortuous passageways, is capable of rapid inflation and deflation and has high burst strengths. Balloon covers having these same characteristics are also described for use with conventional embolectomy balloons or angioplasty balloons.
    Type: Application
    Filed: June 25, 2008
    Publication date: December 18, 2008
    Inventors: Carey V. Campbell, Alvaro J. Laguna, Mark S. Spencer
  • Patent number: 7335184
    Abstract: A balloon catheter. The balloon is of a composite material having the flexibility and elastic characteristics of an elastomeric material, yet exhibiting the growth limits of inelastic materials. The balloon may be provided in various shapes. The balloon may be treated to maintain a substantially constant length during inflation and deflation. The balloon may be provided with regions of porosity for the delivery of therapeutic agents, and may be treated to exhibit regions of distinct compliance. Also disclosed is an apparatus, which may be used to impart the regions of distinct compliance into the balloon.
    Type: Grant
    Filed: September 5, 2003
    Date of Patent: February 26, 2008
    Assignee: Sentient Engineering and Technology
    Inventor: Alvaro J. Laguna
  • Patent number: 6923827
    Abstract: Balloon catheters having the strength and maximum inflated diameter characteristics of an angioplasty balloon and having the recovery characteristics during deflation of an elastic embolectomy balloon. The balloon catheter can be made in very small sizes and has a lubricious and chemically inert outer surface. The balloon catheter is easy to navigate through tortuous passageways, is capable of rapid inflation and deflation and has high burst strengths. Balloon covers having these same characteristics are also described for use with conventional embolectomy balloons or angioplasty balloons.
    Type: Grant
    Filed: November 20, 2002
    Date of Patent: August 2, 2005
    Assignee: Gore Enterprise Holdings, Inc.
    Inventors: Carey V. Campbell, Alvaro J. Laguna, Mark S. Spencer
  • Patent number: 6773447
    Abstract: The present invention provides an improved balloon catheter. The balloon is of a composite material having the flexibility and elastic characteristics of an elastomeric material, yet exhibiting the growth limits of inelastic materials. The balloon may be treated to maintain a substantially constant length during inflation and deflation. The balloon may be provided with regions of porosity for the delivery of therapeutic agents, and may be treated to exhibit regions of distinct compliance. Also disclosed is an apparatus, which may be used to impart the regions of distinct compliance into the balloon.
    Type: Grant
    Filed: July 2, 2002
    Date of Patent: August 10, 2004
    Assignee: Sentient Engineering & Technology, LLC
    Inventor: Alvaro J. Laguna
  • Publication number: 20040098021
    Abstract: A balloon catheter. The balloon is of a composite material having the flexibility and elastic characteristics of an elastomeric material, yet exhibiting the growth limits of inelastic materials. The balloon may be provided in various shapes. The balloon may be treated to maintain a substantially constant length during inflation and deflation. The balloon may be provided with regions of porosity for the delivery of therapeutic agents, and may be treated to exhibit regions of distinct compliance. Also disclosed is an apparatus, which may be used to impart the regions of distinct compliance into the balloon.
    Type: Application
    Filed: September 5, 2003
    Publication date: May 20, 2004
    Applicant: Sentient Engineering & Technology, L.L.C.
    Inventor: Alvaro J. Laguna