Patents by Inventor Alvaro P. M. Bras

Alvaro P. M. Bras has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for assaying non-spermine/spermidine activity of spermidine/spermine N1-acetyltransferase (SSAT)
    Patent number: 6811967
    Abstract: This invention relates to a method for assaying activity of the enzyme spermidine/spermine N1-acetyltransferase (SSAT) using SSAT substrates by detecting acetylated forms of the SSAT substrates. SSAT substrates may include amantadine wherein metabolism of amantadine occurs in part by the action of the inducible enzyme SSAT to produce the acetylated metabolite N-acetylamantadine.
    Type: Grant
    Filed: March 1, 2002
    Date of Patent: November 2, 2004
    Assignee: The University of Manitoba
    Inventors: Daneil S. Sitar, Alvaro P. M. Bras