Abstract: A filament assembly for mounting to a source assembly of a mass spectrometer, the filament assembly comprising a body having one of: an aperture to receive a corresponding spigot provided by a source assembly; or a spigot to be received in a corresponding aperture on a source assembly.

Abstract: A device and method for directing a cannula toward a target location under a patient's skin. The device is handheld and the device operations may be automated. The device includes an imaging probe for imaging the target location, a positioning unit for manipulating a cannula towards the target location, and a processor. The processor receives imaging data from the imaging probe, cannula pose data from at least one cannula position sensor, and device pose data from at least one device position sensor. The target location is identified from the imaging data, and a trajectory for manipulating the cannula towards the target location is determined based on the imaging data, the cannula pose data, and the device pose data. The processor may determine that the trajectory becomes misaligned with the target position, and may update to a corrected trajectory based on the imaging data, cannula pose data, and the device pose data.

Abstract: Disclosed is a fungicidal composition comprising (a) at least one compound selected from the compounds of Formula 1, including all geometric and stereoisomers, tautomers, A-oxides, and salts thereof, wherein E, L, J, A and T are as defined in the disclosure; and (b) at least one additional fungicidal compound. Also disclosed is a method for controlling plant diseases caused by fungal plant pathogens comprising applying to the plant or portion thereof, or to the plant seed, a fungicidally effective amount of a compound of Formula 1, an A-oxide, or salt thereof (e.g., as a component in the aforesaid composition). Also disclosed is a composition comprising: (a) at least one compound selected from the compounds of Formula 1 described above, A-oxides, and salts thereof; and at least one invertebrate pest control compound or agent.

Abstract: A controller (120) for simultaneously tracking multiple sensors in a medical intervention includes a circuit (121-181) that causes the controller (120) to execute a process. The process executed by the circuit (121-181) includes receiving first and second signals respectively from a first and a second passive ultrasound sensor (S2) used in the medical intervention. The first and second signals respectively include first and second sensor information indicative of respective locations of the first and the second passive ultrasound sensor (S2). The process executed by the circuit (121-181) also includes combining (120) the first signal and the second signal for transmission over only one channel, and providing the first signal and the second signal over the only one channel to a system (190) that determines the location of the first passive ultrasound sensor (S1) and the location of the second passive ultrasound sensor (S2) and that has only the one channel to receive the first signal and the second signal.

Abstract: A system for predicting and summarizing medical events from electronic health records includes a computer memory storing aggregated electronic health records from a multitude of patients of diverse age, health conditions, and demographics including medications, laboratory values, diagnoses, vital signs, and medical notes. The aggregated electronic health records are converted into a single standardized data structure format and ordered arrangement per patient, e.g., into a chronological order. A computer (or computer system) executes one or more deep learning models trained on the aggregated health records to predict one or more future clinical events and summarize pertinent past medical events related to the predicted events on an input electronic health record of a patient having the standardized data structure format and ordered into a chronological order.

Abstract: Implementations described herein relate to causing emoji(s) that are associated with a given emotion class expressed by a spoken utterance to be visually rendered for presentation to a user at a display of a client device of the user. Processor(s) of the client device may receive audio data that captures the spoken utterance, process the audio data to generate textual data that is predicted to correspond to the spoken utterance, and cause a transcription of the textual data to be visually rendered for presentation to the user via the display. Further, the processor(s) may determine, based on processing the textual data, whether the spoken utterance expresses a given emotion class. In response to determining that the spoken utterance expresses the given emotion class, the processor(s) may cause emoji(s) that are stored in association with the given emotion class to be visually rendered for presentation to the user via the display.

Abstract: A system and method for determining position information for a device within a body of a subject. The device outputs and/or routes an acoustic signal with a frequency of no more than 20 kHz, which is received by at least a first sensor, positioned externally to the body of the subject. A processing system receives the received signal from the sensor, obtains a value for one or more parameters of the received signal and processes the value(s) to determine position information for the device.

Abstract: A controller for determining shape of an interventional device includes a memory that stores instructions, and a processor that executes the instructions. When executed by the processor, the instructions cause the controller to execute a process that includes controlling an imaging probe to emit at least one tracking beam to an interventional medical device over a period of time comprising multiple different points of time. The process also includes determining a shape of the interventional medical device, based on a response to the tracking beams received over the period of time from a first sensor that moves along the interventional medical device during the period of time relative to a fixed location on the interventional medical device for the period of time.

Abstract: A controller for reducing noise in an ultrasound environment includes memory that stores instructions; and a processor that executes the instructions. When executed by the processor, the instructions cause the controller to execute a process that includes controlling emission, by an ultrasound probe, of multiple beams each at a different combination of time of emission and angle of emission relative to the ultrasound probe. The process also includes identifying repetitive noise from a first source received with the imaging beams at a sensor on an interventional medical device, including a rate at which the repetitive noise from the first source repeats and times at which the repetitive noise from the first source is received. The process also includes interpolating signals based on the imaging beams received at the sensor to offset the repetitive noise from the first source at the times at which the repetitive noise from the first source is received.

Abstract: The present invention relates to a document comprising at least one RFID transponder, the RFID transponder comprising an antenna (3, 23) and an integrated circuit (4, 24) electrically coupled to the antenna (3, 23). The document comprises at least one detachable detuning element (7, 27) electrically coupled to the antenna (3, 23). The invention also relates to a method for manufacturing a document comprising an RFID transponder.

Abstract: A system for determining location of an interventional medical device within a patient includes a controller that controls an ultrasound probe to emit imaging beams at different times and angles relative to the ultrasound probe. The system also includes an interventional medical device with an attached sensor that receives the imaging beams together with repetitive noise. The controller further identifies the repetitive noise received at the sensor, including identifying the rate at which the repetitive noise is repeated and identifying the times at which the repetitive noise is received at the sensor. The controller further offsets the repetitive noise in signals received at the sensor by interpolating the signals based on the imaging beams. The controller determines the location of the interventional medical device based on the offset signals.

Abstract: A system and method for providing guidance in an ultrasound imaging procedure involves presenting graphical user interface elements overlaid onto an external image of the subject's body. The system includes at least one camera for capturing the external image of the subject. The system may utilize trained artificial neural network(s) to identify locations in the external image that correspond to scanning zones of a scanning protocol. A probe placement marker is overlaid at each identified location to indicate the position of the probe's face onto the subject's body for acquiring a target view of the internal anatomy. Additional graphical elements may be presented via the guidance interface and results findings may optionally be overlaid onto the external image of the subject at the completion of the scan. In embodiments herein, imaging guidance is provided solely via the external images of the subject without displaying the ultrasound image data.

Abstract: A system is provided for guiding an interventional instrument (150) to an internal target in a subject. The system includes a guide device (100) configured to rest on an outer surface of the subject and a shape sensing device (140). The guide device includes a holder (120) configured to receive the interventional instrument (150) and to provide an entry trajectory of the interventional instrument (150) for guiding the interventional instrument (150) to the target; and a fastener (130) attached to a portion of the guide device (100). The shape sensing device (140) provides shape sensing data indicating a shape of at least a portion of the shape sensing device (140) secured to the guide device (100) by the fastener (130). The shape sensing data enables determination of a position and orientation of the guide device (100) on the outer surface of the subject.

Abstract: A system and a method for determining a relative position of an ultrasound transceiver with respect to an opening of an interventional device where the opening is within a lumen of the interventional device. Ultrasound transmissions from an ultrasound transceiver, capable of moving through at last part of the lumen and the opening are reflected off the wall or boundary of the lumen. The ultrasound transceiver may receive one or more 5 echoes of the ultrasound transmissions and generate a receive signal comprising the one or more echoes and transmit receive data comprising one or more characteristics of the echo to a data processor. The data processor is configured to identify from the receive data the one or more characteristics and determine a relative position of the ultrasound transceiver with respect to the opening based on the one or more characteristics. A transceiver may be part of 10 a retrofit device with which the interventional device may be equipped during an interventional procedure.

Abstract: Methods, Apparatuses, and Systems of operating a laser atherectomy system to perform an endoscopic atherectomy procedure within a vessel at a therapeutic region of an anatomical condition by use of an atherectomy laser device coupled to an ultrasound imaging probe. The atherectomy laser device operates to generate photoacoustic signals from a light source of the atherectomy laser device to for guidance within the vessel and to characterize tissue about the therapeutic region by delivery of pulsed wavelengths within the vessel, and to perform operations of tissue ablation directed to the anatomical condition. This enables guidance of the atherectomy laser device by feedback from the viewing of photoacoustic images based on photoacoustic signals generated the atherectomy laser device and created in response to changes in acoustic intensity due to changes of optical wavelength monitored by the ultrasound imaging probe.

Abstract: Systems and methods for laser catheter treatment in a vessel lumen. The method includes inserting the laser catheter within the vessel lumen to a location of a treatment area; presenting an image of the treatment area within the vessel lumen based on using an ultrasound (US) imaging system; and, detecting, in real-time, a bubble cloud that is a function of the laser catheter operation (at a prescribed speed and controlling a fluence and a pulse rate) in the treatment area. The method determines a vessel diameter, a real-time location and measurements of the bubble cloud, and estimates a dwell position and dwell time. A dynamic displayed image that is indicative of a progression of the laser catheter treatment is presented, and commands may be generated to modify the laser catheter parameters responsive to the estimated dwell position, the estimated dwell time, and a recommended treatment protocol.

Abstract: 2019PF00643 32 ABSTRACT Disclosed is an ultrasound roadmap image generation system. The system includes a processor configured for communication with an ultrasound imaging device that is movable relative to a patient. The processor receives a first bi-plane or 3D image representative of a first volume within the patient and a second bi-plane or 3D image representative of a second volume within the patient. The processor then registers the first bi-plane or 3D image and the second bi-plane or 3D image to determine the motion between the first bi-plane or 3D image and the second bi-plane or 3D image. The processor then generates a 2D roadmap image of a region of interest by combining the first bi-plane or 3D image and the second bi-plane or 3D image, based on the determined motion; and outputs a screen display comprising the 2D roadmap image.

Abstract: Various embodiments of the present disclosure encompass an endoluminal therapy system employing an endoluminal therapy device (21) and an endoluminal therapy monitoring controller (10). In support an endoluminal procedure, the endoluminal therapy device (21) is controlled to treat a site to be treated within a lumen. The controller (10) is operated to synchronize an activated dwell timing of the endoluminal therapy device (21) within the lumen to a tracked positioning of the endoluminal therapy device (21) contiguous with the site to be treated within the lumen. The controller (10) is further operated to monitor the site to be treated within the lumen induced by the endoluminal therapy device (21) during the synchronization by the controller (10) of the activated dwell timing of the endoluminal therapy device (21) within the lumen to the tracked positioning of the endoluminal therapy device (21) contiguous with the site to be treated within the lumen.

Abstract: A steerable medical catheter includes a tubular body having a longitudinal axis and a distal portion for insertion into a subject, a first pull wire, a second pull wire, and a piezoelectric transducer. The piezoelectric transducer includes a first electrode and a second electrode. At the distal portion of the catheter the first pull wire and the second pull wire are each mechanically coupled to the tubular body at respective first and second offset positions with respect to the longitudinal axis for imparting a curvature on the distal portion of the catheter. At the distal portion of the catheter the first pull wire is electrically connected to the first electrode of the piezoelectric transducer and the second pull wire is electrically connected to the second electrode of the piezoelectric transducer.

Abstract: A method and system is for assisting a user in positioning an ultrasound probe relative to a subject's body. In use, the user moves the probe through a series of positions, and ultrasound image data is captured for each position, the data at each position corresponding to a particular imaging view of the anatomical region being imaged. An assessment procedure (16) is operable to process ultrasound data for different imaging views, and to determine for the data for each view a rating, representative of the suitability of the data for that view for observing one or more anatomical features or deriving one or more clinical parameters from the data. Guidance feedback is generated (18) for the user for assisting the user in positioning the probe, wherein the guidance feedback is based on a history (26) of image view quality over time over the course of the imaging procedure.