Abstract: Taste modifier products and therapeutic methods for encouraging decrease in high calorie food intake by a person are disclosed. A taste modifier product ingested toy a person may comprise one or more sweetness inhibitors and one or more anesthetics. The taste modifier product may decrease sensitivity to sweet and bitter tastes when the product is ingested by the person. One or more coolant ingredients may also be included in a taste modifier product. The ingredients of a taste modifier product may be incorporated into a lozenge, a beverage, a chewing gum, an oral spray, an oral powder, a hard or a soft candy, a dessert or a foodstuff. When consumed by a person, the products may both depress a person's appetite and relieve hunger symptoms. Consequently, a person consuming the products may select smaller portion sizes when eating food and limit high calorie foods.

Abstract: The present invention is directed to a method of making a stable composition comprising growth factors, which may include platelet derived growth factors and transforming growth factors. The method comprises providing human umbilical cord blood plasma containing platelets, but substantially free of whole blood cells, and lysing the platelets to extrude growth factors into the plasma. The plasma may be obtained from multiple donors and pooled to form a homologous plasma mixture. In another embodiment, the growth factors are encapsulated in a liposome formed by a lipid bilayer, wherein the resulting composition remains stable and viable for at least 30 months. The present invention is also directed to the composition produced by the methods of the present invention and the process of applying the composition to a skin defect or wound.

Abstract: A method for formulating a cationic and non-ionic oil in water emulsion, preferably in a cream form, containing growth factors, preferably platelet derived growth factors, specific matrikine peptides, botanicals, emollients, nano-molecules, antioxidants, antiseptics, neuro-peptides, anti-dermatophytics, polysaccharides, sensorial peptides, osmotically driven moisturizers, and siloxane barriers. For application to the feet and other affected parts of the body for the relief of diabetic skin and tissue trauma.

Abstract: Scars, stretch marks, keloids, keratosis, and other skin lesions can be ameliorated through topical application of a composition containing a fortified botanical complex inhibiting tryptase and chymase. A flavonoid with antioxidant properties valuable in inflammatory stress; blocking the release of histamine, inhibiting leukocytic elastase and strengthening the protective properties surrounding the extracellular matrix. Primary wound healing occurs through the release of platelet derived growth factors stimulating the production of procollagen and increasing the density of water holding skin matrix cells which provide unencumbered moisture to the skin. The formula peptides are matrikines They act in synergy to restore and maintain the skin's appearance by activating the neosynthesis of extracellular matrix molecules.