Patents by Inventor Alvin S. Stern

Alvin S. Stern has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • K-RAS MUTATIONS AND ANTAGONISTS
    Publication number: 20190134056
    Abstract: The present application relates to K-Ras mutations, to polynucleotides encoding mutant K-Ras polypeptides, and to methods of identifying small molecule antagonists using K-Ras mutations. The present application also relates to K-Ras small molecule antagonists and use thereof in the treatment of tumors.
    Type: Application
    Filed: March 9, 2018
    Publication date: May 9, 2019
    Applicant: The Trustees of the Stevens Institute of Technolog
    Inventors: Peter TOLIAS, Alvin S. STERN, Kuo-Sen HUANG, Michael Lloyd SABIO, Sidney Wolf TOPIOL
  • Homogeneous human interleukin 2
    Patent number: 5597901
    Abstract: Human interleukin 2 (IL-2) derived from induced human malignant cells has been purified to homogeneity using multiple high performance liquid chromatography (HPLC) steps. The purified IL-2 exhibits potent activity promoting the long-term in vitro culture of antigen-specific effector T-lymphocytes and in modulating lymphocyte reactivity.
    Type: Grant
    Filed: May 25, 1995
    Date of Patent: January 28, 1997
    Assignee: Hoffmann-La Roche Inc.
    Inventor: Alvin S. Stern
  • Homogeneous human interleukin 2
    Patent number: 4490289
    Abstract: Human interleukin 2 (IL-2) derived from induced human malignant cells has been purified to homogeneity using multiple high performance liquid chromatography (HPLC) steps. The purified IL-2 exhibits potent activity promoting the long-term in vitro culture of antigen-specific effector T-lymphocytes and in modulating lymphocyte reactivity.
    Type: Grant
    Filed: September 16, 1982
    Date of Patent: December 25, 1984
    Assignee: Hoffmann-La Roche Inc.
    Inventor: Alvin S. Stern