Patents by Inventor Alvin Thomas

Alvin Thomas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11648320
    Abstract: The present invention provides a biomatrix layer comprising, consisting essentially of or consisting of a sulfated oligosaccharide at a concentration in the range of 0.1 ?M to 1,000 ?M and a peptide-polyethylene glycol-conjugate according to formula (I): PEG-R1-(BX)n (I) wherein B is lysine or arginine, X is selected from alanine, glycine, serine, threonine, tyrosine, glutamic acid or aspartic acid and n is an integer selected from 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19 and 20; R1 may be absent or is a peptide comprising 5 to 30 amino acids; PEG is comprised at a concentration in the range of 0.1 ?M to 1,000 ?M; R1, if present, is comprised at a concentration in the range of 0.1 ?M to 4,000 ?M; (BX)n is comprised at a concentration in the range of 0.25 ?M to 1,000 ?M. The invention further relates to processes for assembling the biomatrix layer.
    Type: Grant
    Filed: June 18, 2018
    Date of Patent: May 16, 2023
    Assignee: DENOVOMATRIX GMBH
    Inventors: Yixin Zhang, Alvin Thomas, Richard Wetzel, Dejan Husman, Robert Wieduwild
  • Patent number: 11166907
    Abstract: The present invention provides a conductive hydrogel comprising a polystyrene sulfonate compound selected from poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS), reduced graphene oxide polystyrene sulfonate (rGO:PSS) and rGO:PEDOT:PSS; and a conjugate of polyethylene glycol (PEG) and a linker-(BX)n oligopeptide of formula (I) PEG-linker-(BX)n??(I) wherein B is lysine or arginine, X is selected from alanine, glycine, serine, threonine, tyrosine, glutamic acid or aspartic acid and n is an integer selected from 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19 and 20. The invention further relates to processes for assembling the conductive hydrogel. The conductive hydrogel can be used in various biomedical applications, such as neuroprostheses, biosensors, nerve grafts, cell culture and encapsulation of cells and microorganisms as well as for drug delivery.
    Type: Grant
    Filed: April 27, 2018
    Date of Patent: November 9, 2021
    Assignee: DENOVOMATRIX GMBH
    Inventors: Yixin Zhang, Yong Xu, Alvin Thomas
  • Publication number: 20210242543
    Abstract: Battery systems according to embodiments of the present technology may include a battery. The battery may include a first electrode terminal and a second electrode terminal accessible along a first surface of the battery. The systems may include a module electrically coupled with the battery. The module may include a circuit board characterized by a first surface and a second surface opposite the first surface. The module may include a mold extending from the first surface of the circuit board toward the battery. The module may include a first conductive tab electrically coupling the module with the first electrode terminal. The module may include a second conductive tab electrically coupling the module with the second electrode terminal. The second conductive tab may extend across the mold substantially parallel to the first surface of the circuit board.
    Type: Application
    Filed: April 1, 2021
    Publication date: August 5, 2021
    Applicant: Apple Inc.
    Inventors: Haran Balaram, Nathan J. Bohney, Pengchuan Wang, Jicheng Yang, Wyeman Chen, Scott Lawson Gooch, Kevin Robert Linke, Alvin Thomas Chang
  • Publication number: 20210145980
    Abstract: The present invention provides a biomatrix layer comprising, consisting essentially of or consisting of a sulfated oligosaccharide at a concentration in the range of 0.1 ?M to 1,000 ?M and a peptide-polyethylene glycol-conjugate according to formula (I): PEG-R1-(BX)n (I) wherein B is lysine or arginine, X is selected from alanine, glycine, serine, threonine, tyrosine, glutamic acid or aspartic acid and n is an integer selected from 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19 and 20; R1 may be absent or is a peptide comprising 5 to 30 amino acids; PEG is comprised at a concentration in the range of 0.1 ?M to 1,000 ?M; R1, if present, is comprised at a concentration in the range of 0.1 ?M to 4,000 ?M; (BX)n is comprised at a concentration in the range of 0.25 ?M to 1,000 ?M. The invention further relates to processes for assembling the biomatrix layer.
    Type: Application
    Filed: June 18, 2018
    Publication date: May 20, 2021
    Applicant: DENOVOMATRIX GMBH
    Inventors: Yixin ZHANG, Alvin THOMAS, Richard WETZEL, Dejan HUSMAN, Robert WIEDUWILD
  • Publication number: 20200188294
    Abstract: The present invention provides a conductive hydrogel comprising a polystyrene sulfonate compound selected from poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS), reduced graphene oxide polystyrene sulfonate (rGO:PSS) and rGO:PEDOT:PSS; and a conjugate of polyethylene glycol (PEG) and a linker-(BX)n oligopeptide of formula (I) PEG-linker-(BX)n ??(I) wherein B is lysine or arginine, X is selected from alanine, glycine, serine, threonine, tyrosine, glutamic acid or aspartic acid and n is an integer selected from 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19 and 20. The invention further relates to processes for assembling the conductive hydrogel. The conductive hydrogel can be used in various biomedical applications, such as neuroprostheses, biosensors, nerve grafts, cell culture and encapsulation of cells and microorganisms as well as for drug delivery.
    Type: Application
    Filed: April 27, 2018
    Publication date: June 18, 2020
    Applicant: DENOVOMATRIX GMBH
    Inventors: Yixin ZHANG, Yong XU, Alvin THOMAS
  • Patent number: 6213330
    Abstract: This invention is directed to providing detecting means on a thermoplastic mold part comprising a cover and a base panel or comprising a cap enclosure and a bottle. The detecting means comprises an interlocking break-away tab which upon initial opening of the container, the tab breaks away. This is particularly useful with compact disc or cassette containers. This invention is also directed to a thermoplastic container having a pivotal hinged cover and base wherein the hinge pin is of a particular design for securing the pivotal cover and base panels at the hinge end.
    Type: Grant
    Filed: November 9, 1993
    Date of Patent: April 10, 2001
    Assignee: Lakewood Industries, Inc.
    Inventors: George Rufo, Jr., Alvin Thomas
  • Patent number: 5785172
    Abstract: A storage tray for holding and receiving at least two compact discs wherein the storage tray has a double rosette consisting of an upper and lower rosette the extremities of the cantilever members (fingers) of which form a circular opening having a common center. The double rosette is on at least the same side of the storage tray. Also a storage container or jewel box consisting of a cover and a base pivotally attached at the same end thereof and containing the storage tray with the double rosette.
    Type: Grant
    Filed: December 28, 1995
    Date of Patent: July 28, 1998
    Assignee: Lakewood Industries, Inc.
    Inventors: David Bolognia, George Rufo, Jr., Alvin Thomas
  • Patent number: 5701997
    Abstract: A storage package for an article and a booklet includes a pair of panels secured together and movable between a closed storage orientation, wherein the panels are substantially overlying with at least an article and a booklet supported by the article disposed intermediate the pair of panels, and an open use orientation, wherein the panels are not substantially overlying and the article and booklet are accessible. A fixed base formed of plastic defines a cavity with a bottom face mounted on one of the panels and an open top face. A floating holder formed of rigid plastic is disposed within the cavity intermediate the faces for receiving and maintaining thereon the article and booklet, the holder being movable between a plurality of positions variably spaced above the cavity bottom face. A spring secured to one of the base and holder biases the holder above the cavity bottom face, thereby to accommodate booklets of varying thickness.
    Type: Grant
    Filed: April 23, 1996
    Date of Patent: December 30, 1997
    Assignee: Ivy Hill Corporation
    Inventors: Patrick J. O'Brien, Alvin Thomas, George Rufo, Jr., Larry Durham, Anthony L. Gelardi
  • Patent number: 5531321
    Abstract: A storage package for an article and a booklet includes a pair of panels secured together and movable between a closed storage orientation, wherein the panels are substantially overlying with at least an article and a booklet supported by the article disposed intermediate the pair of panels, and an open use orientation, wherein the panels are not substantially overlying and the article and booklet are accessible. A fixed base formed of plastic defines a cavity with a bottom face mounted on one of the panels and an open top face. A floating holder formed of rigid plastic is disposed within the cavity intermediate the faces for receiving and maintaining thereon the article and booklet, the holder being movable between a plurality of positions variably spaced above the cavity bottom face. A spring secured to one of the base and holder biases the holder above the cavity bottom face, thereby to accommodate booklets of varying thickness.
    Type: Grant
    Filed: September 19, 1993
    Date of Patent: July 2, 1996
    Assignee: Ivy Hill Corporation
    Inventors: Patrick J. O'Brien, Alvin Thomas, George Rufo, Jr., Larry Durham, Anthony L. Gelardi
  • Patent number: 5425448
    Abstract: A storage package for an article and a booklet includes a pair of panels secured together and movable between a closed storage orientation, wherein the panels are substantially overlying with at least an article and a booklet supported by the article disposed intermediate the pair of panels, and an open use orientation, wherein the panels are not substantially overlying and the article and booklet are accessible. A fixed base formed of plastic defines a cavity with a bottom face mounted on one of the panels and an open top face. A floating holder formed of rigid plastic is disposed within the cavity intermediate the faces for receiving and maintaining thereon the article and booklet, the holder being movable between a plurality of positions variably spaced above the cavity bottom face. A spring secured to one of the base and holder biases the holder above the cavity bottom face, thereby to accommodate booklets of varying thickness.
    Type: Grant
    Filed: May 28, 1993
    Date of Patent: June 20, 1995
    Assignee: Ivy Hill Corporation
    Inventors: Patrick J. O'Brien, Alvin Thomas, George Rufo, Jr., Larry Durham
  • Patent number: D448151
    Type: Grant
    Filed: April 18, 2001
    Date of Patent: September 25, 2001
    Inventor: Alvin Thomas Outlaw