Patents by Inventor Alvin Thomas
Alvin Thomas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11648320Abstract: The present invention provides a biomatrix layer comprising, consisting essentially of or consisting of a sulfated oligosaccharide at a concentration in the range of 0.1 ?M to 1,000 ?M and a peptide-polyethylene glycol-conjugate according to formula (I): PEG-R1-(BX)n (I) wherein B is lysine or arginine, X is selected from alanine, glycine, serine, threonine, tyrosine, glutamic acid or aspartic acid and n is an integer selected from 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19 and 20; R1 may be absent or is a peptide comprising 5 to 30 amino acids; PEG is comprised at a concentration in the range of 0.1 ?M to 1,000 ?M; R1, if present, is comprised at a concentration in the range of 0.1 ?M to 4,000 ?M; (BX)n is comprised at a concentration in the range of 0.25 ?M to 1,000 ?M. The invention further relates to processes for assembling the biomatrix layer.Type: GrantFiled: June 18, 2018Date of Patent: May 16, 2023Assignee: DENOVOMATRIX GMBHInventors: Yixin Zhang, Alvin Thomas, Richard Wetzel, Dejan Husman, Robert Wieduwild
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Patent number: 11166907Abstract: The present invention provides a conductive hydrogel comprising a polystyrene sulfonate compound selected from poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS), reduced graphene oxide polystyrene sulfonate (rGO:PSS) and rGO:PEDOT:PSS; and a conjugate of polyethylene glycol (PEG) and a linker-(BX)n oligopeptide of formula (I) PEG-linker-(BX)n??(I) wherein B is lysine or arginine, X is selected from alanine, glycine, serine, threonine, tyrosine, glutamic acid or aspartic acid and n is an integer selected from 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19 and 20. The invention further relates to processes for assembling the conductive hydrogel. The conductive hydrogel can be used in various biomedical applications, such as neuroprostheses, biosensors, nerve grafts, cell culture and encapsulation of cells and microorganisms as well as for drug delivery.Type: GrantFiled: April 27, 2018Date of Patent: November 9, 2021Assignee: DENOVOMATRIX GMBHInventors: Yixin Zhang, Yong Xu, Alvin Thomas
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Publication number: 20210242543Abstract: Battery systems according to embodiments of the present technology may include a battery. The battery may include a first electrode terminal and a second electrode terminal accessible along a first surface of the battery. The systems may include a module electrically coupled with the battery. The module may include a circuit board characterized by a first surface and a second surface opposite the first surface. The module may include a mold extending from the first surface of the circuit board toward the battery. The module may include a first conductive tab electrically coupling the module with the first electrode terminal. The module may include a second conductive tab electrically coupling the module with the second electrode terminal. The second conductive tab may extend across the mold substantially parallel to the first surface of the circuit board.Type: ApplicationFiled: April 1, 2021Publication date: August 5, 2021Applicant: Apple Inc.Inventors: Haran Balaram, Nathan J. Bohney, Pengchuan Wang, Jicheng Yang, Wyeman Chen, Scott Lawson Gooch, Kevin Robert Linke, Alvin Thomas Chang
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Publication number: 20210145980Abstract: The present invention provides a biomatrix layer comprising, consisting essentially of or consisting of a sulfated oligosaccharide at a concentration in the range of 0.1 ?M to 1,000 ?M and a peptide-polyethylene glycol-conjugate according to formula (I): PEG-R1-(BX)n (I) wherein B is lysine or arginine, X is selected from alanine, glycine, serine, threonine, tyrosine, glutamic acid or aspartic acid and n is an integer selected from 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19 and 20; R1 may be absent or is a peptide comprising 5 to 30 amino acids; PEG is comprised at a concentration in the range of 0.1 ?M to 1,000 ?M; R1, if present, is comprised at a concentration in the range of 0.1 ?M to 4,000 ?M; (BX)n is comprised at a concentration in the range of 0.25 ?M to 1,000 ?M. The invention further relates to processes for assembling the biomatrix layer.Type: ApplicationFiled: June 18, 2018Publication date: May 20, 2021Applicant: DENOVOMATRIX GMBHInventors: Yixin ZHANG, Alvin THOMAS, Richard WETZEL, Dejan HUSMAN, Robert WIEDUWILD
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Publication number: 20200188294Abstract: The present invention provides a conductive hydrogel comprising a polystyrene sulfonate compound selected from poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS), reduced graphene oxide polystyrene sulfonate (rGO:PSS) and rGO:PEDOT:PSS; and a conjugate of polyethylene glycol (PEG) and a linker-(BX)n oligopeptide of formula (I) PEG-linker-(BX)n ??(I) wherein B is lysine or arginine, X is selected from alanine, glycine, serine, threonine, tyrosine, glutamic acid or aspartic acid and n is an integer selected from 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19 and 20. The invention further relates to processes for assembling the conductive hydrogel. The conductive hydrogel can be used in various biomedical applications, such as neuroprostheses, biosensors, nerve grafts, cell culture and encapsulation of cells and microorganisms as well as for drug delivery.Type: ApplicationFiled: April 27, 2018Publication date: June 18, 2020Applicant: DENOVOMATRIX GMBHInventors: Yixin ZHANG, Yong XU, Alvin THOMAS
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Patent number: 6213330Abstract: This invention is directed to providing detecting means on a thermoplastic mold part comprising a cover and a base panel or comprising a cap enclosure and a bottle. The detecting means comprises an interlocking break-away tab which upon initial opening of the container, the tab breaks away. This is particularly useful with compact disc or cassette containers. This invention is also directed to a thermoplastic container having a pivotal hinged cover and base wherein the hinge pin is of a particular design for securing the pivotal cover and base panels at the hinge end.Type: GrantFiled: November 9, 1993Date of Patent: April 10, 2001Assignee: Lakewood Industries, Inc.Inventors: George Rufo, Jr., Alvin Thomas
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Patent number: 5785172Abstract: A storage tray for holding and receiving at least two compact discs wherein the storage tray has a double rosette consisting of an upper and lower rosette the extremities of the cantilever members (fingers) of which form a circular opening having a common center. The double rosette is on at least the same side of the storage tray. Also a storage container or jewel box consisting of a cover and a base pivotally attached at the same end thereof and containing the storage tray with the double rosette.Type: GrantFiled: December 28, 1995Date of Patent: July 28, 1998Assignee: Lakewood Industries, Inc.Inventors: David Bolognia, George Rufo, Jr., Alvin Thomas
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Patent number: 5701997Abstract: A storage package for an article and a booklet includes a pair of panels secured together and movable between a closed storage orientation, wherein the panels are substantially overlying with at least an article and a booklet supported by the article disposed intermediate the pair of panels, and an open use orientation, wherein the panels are not substantially overlying and the article and booklet are accessible. A fixed base formed of plastic defines a cavity with a bottom face mounted on one of the panels and an open top face. A floating holder formed of rigid plastic is disposed within the cavity intermediate the faces for receiving and maintaining thereon the article and booklet, the holder being movable between a plurality of positions variably spaced above the cavity bottom face. A spring secured to one of the base and holder biases the holder above the cavity bottom face, thereby to accommodate booklets of varying thickness.Type: GrantFiled: April 23, 1996Date of Patent: December 30, 1997Assignee: Ivy Hill CorporationInventors: Patrick J. O'Brien, Alvin Thomas, George Rufo, Jr., Larry Durham, Anthony L. Gelardi
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Patent number: 5531321Abstract: A storage package for an article and a booklet includes a pair of panels secured together and movable between a closed storage orientation, wherein the panels are substantially overlying with at least an article and a booklet supported by the article disposed intermediate the pair of panels, and an open use orientation, wherein the panels are not substantially overlying and the article and booklet are accessible. A fixed base formed of plastic defines a cavity with a bottom face mounted on one of the panels and an open top face. A floating holder formed of rigid plastic is disposed within the cavity intermediate the faces for receiving and maintaining thereon the article and booklet, the holder being movable between a plurality of positions variably spaced above the cavity bottom face. A spring secured to one of the base and holder biases the holder above the cavity bottom face, thereby to accommodate booklets of varying thickness.Type: GrantFiled: September 19, 1993Date of Patent: July 2, 1996Assignee: Ivy Hill CorporationInventors: Patrick J. O'Brien, Alvin Thomas, George Rufo, Jr., Larry Durham, Anthony L. Gelardi
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Patent number: 5425448Abstract: A storage package for an article and a booklet includes a pair of panels secured together and movable between a closed storage orientation, wherein the panels are substantially overlying with at least an article and a booklet supported by the article disposed intermediate the pair of panels, and an open use orientation, wherein the panels are not substantially overlying and the article and booklet are accessible. A fixed base formed of plastic defines a cavity with a bottom face mounted on one of the panels and an open top face. A floating holder formed of rigid plastic is disposed within the cavity intermediate the faces for receiving and maintaining thereon the article and booklet, the holder being movable between a plurality of positions variably spaced above the cavity bottom face. A spring secured to one of the base and holder biases the holder above the cavity bottom face, thereby to accommodate booklets of varying thickness.Type: GrantFiled: May 28, 1993Date of Patent: June 20, 1995Assignee: Ivy Hill CorporationInventors: Patrick J. O'Brien, Alvin Thomas, George Rufo, Jr., Larry Durham
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Patent number: D448151Type: GrantFiled: April 18, 2001Date of Patent: September 25, 2001Inventor: Alvin Thomas Outlaw