Abstract: The present invention relates to a method for manufacturing a customized implant comprising the steps of obtaining a plurality of medical images of a bone region with a defect area; converting the medical images into a three-dimensional data; designing a mould customized for the defect area based on the three-dimensional data to produce a customized mould; and fabricating a customized implant from a biocompatible plate using the customized mould via an additive manufacturing technique.

Abstract: This invention relates to a multipoint stamping mould for forming a customised implant mould surface comprising a primary stamping unit (100) having a plurality of rods (101) positioned adjacent to and in contact with one another, each rod (101) having a rough surface along its longitudinal axis and a mould surface defining end (103), wherein the rods (101) are slidable about the longitudinal axis to thereby form a customised implant mould surface by the mould surface defining ends (103) of the rods, according to a predetermined implant surface of the customised implant; and a clamping means (105) for locking the plurality of rods (101) into a position that defines the mould surface. Preferably, the multipoint stamping mould further comprises a secondary stamping unit (200) positioned opposite and corresponding to the primary stamping unit (100).

Abstract: A method for manufacturing a three-dimensional anatomical structure comprising the steps of obtaining a plurality of medical images containing at least one anatomical region of interest, wherein each anatomical region of interest is defined based on a grey level value on the medical images; segmenting each medical image based on the anatomical region of interest to obtain the grey level value; converting the grey level values of the respective segmented medical images into vector data; interpolating the vector data of each segmented medical image to form a three-dimensional data; and producing a three-dimensional anatomical structure of the region of interest from the three-dimensional data.

Abstract: A haemostatic agent delivery device (100) comprising an external tube (101) having a handle (102) mounted at its proximal end and an opening (104) located at its distal end for delivering a haemostatic agent over and sucking blood at a haemorrhagic site simultaneously; and an internal tube (109) having an absorbent (105) across its distal end, a controller (106) and at least one connecting means (107) at its proximal end for loading of haemostatic agent or channeling of sucking force under the trigger of the controller (106); wherein in use the internal tube (109) is introduced into the external tube (101) and pushed along the external tube (101) distally to cause the suction of blood through the absorbent (105) while simultaneously causes compression of the haemostatic agent over the haemorrhagic site.

Abstract: Disclosed herein is a peptide for inhibiting growth of bacterial pathogens in a biological sample, characterized by an amino acid sequence selected from a group consisting of Gly-Leu-Phe-Asp-Lys-Trp-Ala-Trp-Trp-Arg-Trp-Arg-Arg (SEQ ID NO:1), Gly-Leu-Phe-Asp-Ile-Trp-Ala-Trp-Trp-Arg-Trp-Arg-Arg (SEQ ID NO:2), Gly-Leu-Phe-Asp-Ile-Trp-Lys-Trp-Trp-Arg-Trp-Arg-Arg (SEQ ID No:3), Gly-Leu-Phe-Asp-Ile-Trp-Lys-Lys-Trp-Arg-Trp-Arg-Arg (SEQ ID NO:4), and Gly-Leu-Phe-Asp-Ile-Trp-Lys-Lys-Leu-Arg-Trp-Arg-Arg (SEQ ID NO:5).

Abstract: Disclosed herein is a peptide for inhibiting growth of bacterial pathogens in a biological sample, characterized by an amino acid sequence selected from a group consisting of Pro-His-Trp-Trp-Lys-Trp-Ala-Trp-Trp-His-His-Arg-Arg (SEQ ID NO:1), Lys-His-Trp-Trp-Lys-His-Asp-Trp-Trp-Arg-Trp-Arg-Arg (SEQ ID NO:2), and Ile-Leu-Trp-Trp-Leu-Leu-Ala-Trp-Trp-Arg-Trp-Pro-His (SEQ ID NO:3).