Patents by Inventor Alyson E. Mitchell

Alyson E. Mitchell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibition of glutathione transferase by haloenol lactones
    Patent number: 6495370
    Abstract: This invention relates to novel haloenol lactone compounds. These compounds have the following general structure: in which Ar is an aryl group and Y is a haloenol lactone moiety. The compounds of the invention are useful for the specific measurement of particular isoenzymes of glutathione S-transferase. Measurement of glutathione S-transferase isoenzymes has importance in diagnostic medicine. The compounds of the invention are also useful for treatment of drug resistance in cancer and for preventing herbicide resistance in plants.
    Type: Grant
    Filed: August 15, 2000
    Date of Patent: December 17, 2002
    Assignee: The Regents of the University of California
    Inventors: A. Daniel Jones, Alyson E. Mitchell, Bruce D. Hammock, Jiang Zheng
  • Inhibition of glutathione transferase by haloenol lactones
    Patent number: 6103665
    Abstract: This invention relates to novel haloenol lactone compounds. These compounds have the following general structure: ##STR1## in which Ar is an aryl group and Y is a haloenol lactone moiety. The compounds of the invention are useful for the specific measurement of particular isoenzymes of glutathione S-transferase. Measurement of glutathione S-transferase isoenzymes has importance in diagnostic medicine. The compounds of the invention are also useful for treatment of drug resistance in cancer and for preventing herbicide resistance in plants.
    Type: Grant
    Filed: June 15, 1998
    Date of Patent: August 15, 2000
    Assignee: The Regents of the University of California
    Inventors: A. Daniel Jones, Alyson E. Mitchell, Bruce D. Hammock, Jiang Zheng
  • Inhibition of glutathione transferase by haloenol lactones
    Patent number: 5767147
    Abstract: This invention relates to novel haloenol lactone compounds. These compounds have the following general structure: ##STR1## in which Ar is an aryl group and Y is a haloenol lactone moiety. The compounds of the invention are useful for the specific measurement of particular isoenzymes of glutathione S-transferase. Measurement of glutathione S-transferase isoenzymes has importance in diagnostic medicine. The compounds of the invention are also useful for treatment of drug resistance in cancer and for preventing herbicide resistance in plants.
    Type: Grant
    Filed: April 21, 1995
    Date of Patent: June 16, 1998
    Assignee: The Regents of the University of California
    Inventors: A. Daniel Jones, Alyson E. Mitchell, Bruce D. Hammock, Jiang Zheng