Patents by Inventor Amal Ayoub

Amal Ayoub has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Surface-modified heavy metal nanoparticles, compositions and uses thereof
    Patent number: 9486480
    Abstract: Surface-modified heavy metal nanoparticles, including a heavy metal core and a coating layer, the coating layer having at least one ligand, conjugated to polyethylene glycol, the at least one ligand is selected from N-acetyl cysteine, albumin, cysteine, methionine, glutathione, amino thiols, thio-carboxylic acids, ammonia, amines, diamines or any combination thereof. Compositions including surface-modified heavy metal nanoparticles and uses thereof in treatment and diagnosis of various conditions.
    Type: Grant
    Filed: December 8, 2015
    Date of Patent: November 8, 2016
    Assignee: METALLO THERAPY LTD.
    Inventors: Amal Ayoub, Nassim Safadi, Sobhi Basheer
  • Surface-Modified Heavy Metal Nanoparticles, Compositions And Uses Thereof
    Publication number: 20160158281
    Abstract: Surface-modified heavy metal nanoparticles, including a heavy metal core and a coating layer, the coating layer having at least one ligand, conjugated to polyethylene glycol, the at least one ligand is selected from N-acetyl cysteine, albumin, cysteine, methionine, glutathione, amino thiols, thio-carboxylic acids, ammonia, amines, diamines or any combination thereof. Compositions including surface-modified heavy metal nanoparticles and uses thereof in treatment and diagnosis of various conditions.
    Type: Application
    Filed: December 8, 2015
    Publication date: June 9, 2016
    Inventors: Amal Ayoub, Nassim Safadi, Sobhi Basheer
  • Surface-modified heavy metal nanoparticles, compositions and uses thereof
    Patent number: 9242003
    Abstract: Surface-modified heavy metal nanoparticles, including a heavy metal core and a coating layer, the coating layer having at least one ligand, conjugated to polyethylene glycol, the at least one ligand is selected from N-acetyl cysteine, albumin, cysteine, methionine, glutathione, amino thiols, thio-carboxylic acids, ammonia, amines, diamines or any combination thereof. Compositions including surface-modified heavy metal nanoparticles and uses thereof in treatment and diagnosis of various conditions.
    Type: Grant
    Filed: August 5, 2013
    Date of Patent: January 26, 2016
    Inventors: Amal Ayoub, Nassim Safadi, Sobhi Basheer
  • Modified Platinum Compounds
    Publication number: 20140135390
    Abstract: Platinum compounds, modified by conjugation with thiol-containing moieties, such as cysteine or N-acetyl cystein (NAC), and pharmaceutical compositions including the modified platinum compounds. Methods for treatment of a malignancy including administering and activating the modified platinum compounds.
    Type: Application
    Filed: January 21, 2014
    Publication date: May 15, 2014
    Inventor: Amal Ayoub
  • Surface-Modified Heavy Metal Nanoparticles, Compositions And Uses Thereof
    Publication number: 20140030345
    Abstract: Surface-modified heavy metal nanoparticles, including a heavy metal core and a coating layer, the coating layer having at least one ligand, conjugated to polyethylene glycol, the at least one ligand is selected from N-acetyl cysteine, albumin, cysteine, methionine, glutathione, amino thiols, thio-carboxylic acids, ammonia, amines, diamines or any combination thereof. Compositions including surface-modified heavy metal nanoparticles and uses thereof in treatment and diagnosis of various conditions.
    Type: Application
    Filed: August 5, 2013
    Publication date: January 30, 2014
    Inventors: Amal Ayoub, Nassim Safadi, Sobhi Basheer
  • Thulium-containing low dose rate brachytherapy seed
    Publication number: 20100099940
    Abstract: A low dose rate brachytherapy seed having activity in the range between 0.5 and 10 millicurie, preferably less than 3 millicurie, comprising thulium-170 placed within a casing and at least one layer of a radiation emission modifying metal, said layer being provided either internally within the casing or on the outer surface thereof. The radiation emission modifying metal is preferably gold.
    Type: Application
    Filed: September 10, 2009
    Publication date: April 22, 2010
    Applicant: BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY
    Inventors: Gad Shani, Amal Ayoub