Patents by Inventor Amala kishan Kompella

Amala kishan Kompella has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Acid addition salts of (3,5-Bis trifluoromethyl)-N-[4-methyl-3-(4-pyridin-3yl-pyrimidin-2ylamino)-phenyl]-benzamide
    Patent number: 8735415
    Abstract: The present invention relates to acid addition salts of the pharmaceutically active compound (3,5-Bistrifluoromethyl)-N-[4-methyl-3-(4-pyridin-3yl-pyrimidin-2ylamino)-phenyl]-benzamide(I): Development Code—AN019 The invention also relates to processes for the preparation these acid addition salts and to their use as anti tumor agent in humans.
    Type: Grant
    Filed: November 4, 2011
    Date of Patent: May 27, 2014
    Assignee: Natco Pharma Limited
    Inventors: Amala Kishan Kompella, Sreenivas Rachakonda, Bhujanga rao Adibhatla Kali Satya, Venkaiah Chowdary Nannapaneni
  • PROCESS FOR THE PREPARATION OF BOSENTAN MONOHYDRATE
    Publication number: 20130245259
    Abstract: The invention relates to improved processes for the preparation of bosentan monohydrate which provide higher yield and purity.
    Type: Application
    Filed: March 16, 2012
    Publication date: September 19, 2013
    Applicant: Natco Pharma Limited
    Inventors: Amala Kishan Kompella, Srinivasu Kasa, Veera Swamy Balina, Subhash Kusumba, Kali Satya Bhujanga Rao Adibhatla, Venkaiah Chowdary Nannapaneni
  • Phenylaminopyrimidine derivatives as inhibitors of bcr-abl kinase
    Patent number: 8183253
    Abstract: The present invention relates to novel phenylaminopyrimidine derivatives, pharmaceutical compositions containing the novel phenylaminopyrimidine derivatives, and processes for their preparation. These compounds are candidates for the treatment of chronic myeloid leukemia.
    Type: Grant
    Filed: March 4, 2008
    Date of Patent: May 22, 2012
    Assignee: Natco Pharma Limited
    Inventors: Amala Kishan Kompella, Bhujanga Rao Adibhatla Kali Satya, Sreenivas Rachakonda, Nannapaneni Venkaiah Chowdary
  • ACID ADDITION SALTS OF (3,5-BIS TRIFLUOROMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3YL-PYRIMIDIN-2YLAMINO)-PHENYL]-BENZAMIDE
    Publication number: 20120077833
    Abstract: The present invention relates to acid addition salts of the pharmaceutically active compound (3,5-Bistrifluoromethyl)-N-[4-methyl-3-(4-pyridin-3yl-pyrimidin-2ylamino)-phenyl]-benzamide(I): Development Code—AN019 The invention also relates to processes for the preparation these acid addition salts and to their use as anti tumor agent in humans.
    Type: Application
    Filed: November 4, 2011
    Publication date: March 29, 2012
    Applicant: Natco Pharma Limited
    Inventors: Amala Kishan KOMPELLA, Sreenivas Rachakonda, Bhujanga rao Adibhatla Kali Satya, Venkaiah Chowdary Nannapaneni
  • Crystal form of phenylamino pyrimidine derivatives
    Patent number: 8067422
    Abstract: The present invention relates to a particular form of the (3,5-bis trifluoromethyl)-N-[4-methyl-3-(4-pyridin-3yl-pyrimidin-2ylamino)-phenyl]-benzamide (formula I), processes for the preparation thereof, pharmaceutical compositions containing this crystal form, and their use as anti tumor agent in humans.
    Type: Grant
    Filed: March 4, 2008
    Date of Patent: November 29, 2011
    Assignee: Natco Pharma Limited
    Inventors: Amala Kishan Kompella, Bhujanga Rao Adibhatla Kali Satya, Sreenivas Rachakonda, Nannapaneni Venkaiah Chowdary
  • ACID ADDITION SALTS OF (3,5-BIS TRIFLUOROMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3YL-PYRIMIDIN-2YLAMINO)-PHENYL]-BENZAMIDE
    Publication number: 20110190328
    Abstract: The present invention relates to acid addition salts of the pharmaceutically active compound (3,5-Bistrifluoromethyl)-N-[4-methyl-3-(4-pyridin-3yl-pyrimidin-2ylamino)-phenyl]-benzamide(I): The invention also relates to processes for the preparation these acid addition salts and to their use as anti tumor agent in humans.
    Type: Application
    Filed: March 22, 2011
    Publication date: August 4, 2011
    Applicant: Natco Pharma Limited
    Inventors: Amala Kishan Kompella, Sreenivas Rachakonda, Kali Satya Bhujanga Rao ADIBHATLA, Venkaiah Chowdary Nannapaneni
  • Intermediates and a process employing the intermediates for the preparation of (3-trifluoromethylsulfonyl)-N-[4-methyl-3-(4-pyridin-3yl-pyrimidin-2ylamino)-phenyl]-benzamide
    Patent number: 7939541
    Abstract: This invention relates to a process for the preparation of (3-trifluoromethylsulfonyl)-N-[4-methyl-3-(4-pyridin-3yl-pyrimidin-2ylamino)-phenyl]-benzamide (formula (I)) starting from 4-methyl-2-nitro-aniline (formula (II)) through intermediates (3-trifluoromethylsulfonyl)-N-[4-methyl-3-nitrophenyl]-benzamide (formula (III)), (3-trifluoromethylsulfonyl)-N-[3-amino-4-methylphenyl]-benzamide (formula (IV)) and (3-trifluoromethylsulfonyl)-N-[3-guanidino-4-methylphenyl]-benzamide (formula (V)). This invention also relates to processes for the preparation of these intermediates.
    Type: Grant
    Filed: March 4, 2008
    Date of Patent: May 10, 2011
    Assignee: Natco Pharma Limited
    Inventors: Amala kishan Kompella, Bhujanga rao Adibhatla Kali Satya, Sreenivas Rachakonda, Nannapaneni Venkaiah Chowdary
  • Phenylaminopyrimidine derivatives as inhibitors of BCR-ABL kinase
    Patent number: 7910598
    Abstract: The present invention relates to novel intermediates useful for the preparation of novel phenylaminopyrimidine derivatives, novel phenylaminopyrimidine derivatives. Pharmaceutical composition containing the novel phenylaminopyrimidine derivatives and processes for their preparation. The invention particularly relates to novel Phenyl pyrimidine amine derivatives of the general formula (I). The novel compounds of the formula 1 can be used in the therapy of Chronic Myeloid Leukemia (CML). Since the IC50; 191 values of these molecules are in the range 0.1 to 10.0 nm, these novel compounds are potentially useful for the treatment of CML.
    Type: Grant
    Filed: March 5, 2007
    Date of Patent: March 22, 2011
    Assignee: Natco Pharma Limited
    Inventors: Amala kishan Kompella, Bhujanga rao Adibhatla Kali Satya, Sreenivas Rachakonda, Khadgapathi Podili, Nannapaneni Venkaiah Chowdary
  • CRYSTAL FORM OF PHENYLAMINO PYRIMIDINE DERIVATIVES
    Publication number: 20090227611
    Abstract: The present invention relates to a particular form of the (3,5-bis trifluoromethyl)-N-[4-methyl-3-(4-pyridin-3yl-pyrimidin-2ylamino)-phenyl]-benzamide (formula I), processes for the preparation thereof, pharmaceutical compositions containing this crystal form, and their use as anti tumor agent in humans.
    Type: Application
    Filed: March 4, 2008
    Publication date: September 10, 2009
    Applicant: Natco Pharma Limited
    Inventors: Amala kishan Kompella, Bhujanga rao Adibhatla Kali Satya, Sreenivas Rachakonda, Nannapaneni Venkaiah Chowdary
  • PHENYLAMINOPYRIMIDINE DERIVATIVES AS INHIBITORS OF BCR-ABL KINASE
    Publication number: 20080306100
    Abstract: The present invention relates to novel intermediates useful for the preparation of novel phenylaminopyrimidine derivatives, novel phenylaminopyrimidine derivatives. Pharmaceutical composition containing the novel phenylaminopyrimidine derivatives and processes for their preparation. The invention particularly relates to novel Phenyl pyrimidine amine derivatives of the general formula (I). The novel compounds of the formula 1 can be used in the therapy of Chronic Myeloid Leukemia (CML). Since the IC50; 191 values of these molecules are in the range 0.1 to 10.0 nm, these novel compounds are potentially useful for the treatment of CML. The present invention relates to a particular form of the (3,5-bis trifluoromethyl)-N-[4-methyl-3-(4-pyridin-3yl-pyrimidin-2ylamino)-phenyl]-benzamide (formula I), processes for the preparation thereof, pharmaceutical compositions containing this crystal form, and their use as anti tumor agent in humans.
    Type: Application
    Filed: March 4, 2008
    Publication date: December 11, 2008
    Applicant: Natco Pharma Limited
    Inventors: Amala Kishan KOMPELLA, Bhujanga Rao ADIBHATLA KALI SATYA, Sreenivas RACHAKONDA, Nannapaneni VENKAIAH CHOWDARY
  • INTERMEDIATES AND A PROCESS EMPLOYING THE INTERMEDIATES FOR THE PREPARATION OF (3-TRIFLUOROMETHYLSULFONYL)-N-[4-METHYL-3-(4-PYRIDIN-3YL-PYRIMIDIN-2YLAMINO)-PHENYL]-BENZAMIDE
    Publication number: 20080249121
    Abstract: This invention relates to a process for the preparation of (3-trifluoromethylsulfonyl)-N-[4-methyl-3-(4-pyridin-3yl-pyrimidin-2ylamino)-phenyl]-benzamide (formula (I)) starting from 4-methyl-2-nitro-aniline (formula (II)) through intermediates (3-trifluoromethylsulfonyl)-N-[4-methyl-3-nitrophenyl]-benzamide (formula (III)), (3-trifluoromethylsulfonyl)-N-[3-amino-4-methylphenyl]-benzamide (formula (IV)) and (3-trifluoromethylsulfonyl)-N-[3-guanidino-4-methylphenyl]-benzamide (formula (V)). This invention also relates to processes for the preparation of these intermediates.
    Type: Application
    Filed: March 4, 2008
    Publication date: October 9, 2008
    Applicant: Natco Pharma Limited
    Inventors: Amala Kishan Kompella, Bhujanga rao Adibhatla Kali Satya, Sreenivas Rachakonda, Nannapaneni Venkaiah Chowdary