Abstract: Fluid connector systems including first and second connector portions couplable together to form a fluid pathway therethrough and can resist separation or permit separation as desired. A connector portion can include a connector housing and a cover portion. The connector housing includes a connector body and an engagement portion. The connector body defines a tubing opening and a mating opening. The connector body defines a flow path between the tubing opening and the mating opening. The engagement portion at least partially surrounds the connector body. The engagement portion defines an engagement lip extending radially toward the connector body and is configured to releasably engage the connector housing. The flow path includes at least one portion that is normal to the engagement portion. Fluid flow through the flow path exerts a normal force on the connector housing and prevent release of the connector housing with the mating connector portion.

Abstract: Fluid connector systems including first and second connector portions couplable together to form a fluid pathway therethrough and can selectively resist or permit separation as desired. A connector portion can include a connector housing and a cover portion. The connector housing includes a connector body and an engagement portion. The connector body defines a housing volume, a luer opening and a mating opening. The housing volume is in fluid communication with the luer opening and the mating opening. The engagement portion may include an engagement lip extending radially toward the connector body. The engagement lip is configured to releasably engage the connector housing with a mating connector portion. The cover portion is configured to selectively surround the engagement portion of the connector housing. The cover portion is slidable to engage with the engagement portion of the connector housing and prevent release of the connector housing with the mating connector portion.

Abstract: A needle guard assembly includes a needle cannula defining a lumen having a proximal end, a distal end with a sharpened tip, and a tubular body extending between the proximal end and the distal end. The needle guard assembly also includes a needle hub connected to the proximal end of the needle cannula configured to be mounted to a fluid delivery device to provide fluid communication between the fluid delivery device and the lumen of the needle cannula and a liquid-permeable cover member extending over at least the distal end of the needle cannula having a proximal end engaged to the needle hub and a closed distal end enclosing the distal tip of the needle cannula.

Abstract: A coupler including a first connector having a first end, a second end opposite the first end, a first opening, and a first valve disposed between the first end and the second end, the first valve having a compressed and an expanded state, the first valve extending through the first opening when the first valve is in the expanded state and a second connector having a coupling portion, a second opening, and a second valve disposed at least partially within the coupling portion. The second valve having a compressed and an expanded state, the second valve extending at least partially through the second opening when the second valve is in the expanded state. The first valve and the second valve are in the compressed state when the first connector is coupled to the second connector such that a fluid pathway is formed through the first connector and the second connector.

Abstract: A coupler including a first connector having a mating portion with a first opening, and a first torsion member disposed within the mating portion with a first channel. The first torsion member being rotatable relative to the mating portion. The coupler including a second connector having a second torsion member with a second channel, and a coupling portion having a second opening and at least partially disposed within the second torsion member. The second torsion member configured to couple to the first torsion member to couple the first connector to the second connector such that rotation of the second torsion member causes rotation of the first torsion member to cause alignment of the first channel, the first opening, the second channel, and the second opening to form a fluid pathway. The first connector is configured to decouple from the second connector in response to a force exceeding a threshold force.

Abstract: A protective cap engageable with a needle-free connector of an IV catheter assembly includes a collar member defining a central opening within the needle-free connector may be received and a cover member attached to the collar member so as to be pivotable or slideable relative thereto, the cover member moveable between a first position where an end connection of the needle-free connector is covered by the cover member and a second position where the end connection of the needle-free connector is uncovered from the cover member. The protective cap also includes a lever member attached to the cover member and engageable by a user to move the lever member from a non-actuated position to an actuated position. With the lever member in the non-actuated position, the cover member is in the first position, and with the lever member in the actuated position, the cover member is in the second position.

Abstract: Described herein is an add-on device for an intravenous (IV) set hand pump comprising a first member configured to actuate the handpump, a second member hingedly connected to the first member and configured to receive the hand pump, wherein, when actuated, the add-on device is configured to increase a fluid flow rate downstream of the IV set hand pump beyond a maximum gravity-based fluid flow rate of the IV set.

Abstract: Fluid connector assemblies that seal off fluid paths in the respective connectors are disclosed. When connectors of a fluid connector assembly are connected to each other, respective compressible members in the connectors are displaced, allowing downstream fluid passage through the fluid connector assembly. The connectors maintain a connection by a snap mechanism that provides a threshold retention force. When an external force greater than the threshold force is applied to the fluid connector assembly, the snap mechanism may no longer maintain the connectors together, causing the connectors to decouple from each other. However, each of the compressible members can return to their respective original positions and shapes to seal off respective fluid paths in the connectors, thus preventing further downstream and upstream flow through the fluid connector assembly and limiting or preventing fluid loss.

Abstract: A pressure detection system includes a body having an internal chamber with input and output ports and a flexible membrane fluidically sealed to an exposed opening of the chamber to prevent a fluid passing through the chamber from passing through the exposed opening. The membrane is configured to change shape responsive to an increase in pressure caused by the fluid within the chamber satisfying a predetermined threshold. In some implementations, the membrane includes or is part of an identification mechanism which moves outwards, away from the chamber, as the pressure increases to indicate the pressure increase. In some implementations, the identification mechanism includes markings on the surface of the membrane, and an image sensing device reads the markings, and provides an indication of a current pressure associated with the fluid in the chamber based on a variation in the markings from a default state.

Abstract: Fluid clamps are described herein. A fluid clamp includes a clamp body and a rotating body. The clamp body includes a first and second valve element. Each valve element includes a valve extension portion and a valve end portion extending from the valve extension portion. The first and second valve elements are disposed opposite to each other to allow a tubing to pass between the first and second valve elements. The rotating body is rotatably coupled to the clamp body. The rotation of the rotating body moves the valve end portion of at least one of the first and second valve elements to adjust a flow rate through the tubing.

Abstract: An IV blood set foot pump includes a base plate, a squeezing plate movably coupled to the base plate by a pivot member and a biasing member coupled to the base plate and the squeezing plate. The biasing member is configured to exert a biasing force against the squeezing plate when the biasing member is in a compressed state. One of the base plate and the squeezing plate comprises a cavity configured to receive an IV pump bulb. IV sets with IV blood set foot pumps and methods of operating IV blood set foot pumps are also provided.

Abstract: A levered flow regulation clamp assembly for adjusting the fluid flow rate in a connector tube of an infusion set is provided. The levered flow regulation clamp assembly includes a housing to receive the connector tube and a slider rotatably engaged within the housing and configured to compress the connector tube to provide a fluid flow adjustment. Infusion sets and methods of adjusting fluid flow rates are also provided.

Abstract: A method for making a composite polyamide membrane comprising a porous support and a thin film polyamide layer, wherein the method includes the steps of applying a polar solution comprising a polyfunctional amine monomer and a non-polar solution comprising a polyfunctional acyl halide monomer to a surface of a porous support and interfacially polymerizing the monomers to form a thin film polyamide layer. The method is characterized by including a substituted benzamide monomer within the non-polar solution.

Abstract: A method for making a composite polyamide membrane including a porous support and a thin film polyamide layer, wherein the method includes the step of applying a polyfunctional amine monomer and a tetraacyl acyl halide monomer represented by Formula (I) to a surface of the porous support and interfacially polymerizing the monomers to form a thin film polyamide layer; wherein A is selected from: oxygen (—O—); carbon (—C—); silicon (—Si—); each of which may be unsubstituted or substituted, e.g. with alkyl groups of 1-4 carbon atoms; or a carbonyl group (—C(O)—), X is the same or different and is selected from a halogen, and Y is selected from halogen and hydroxide.

Abstract: A method for making a composite polyamide membrane comprising the steps of applying a polyfunctional amine monomer and polyfunctional acyl halide monomer to a surface of the porous support and interfacially polymerizing the monomers to form a thin film polyamide layer, wherein the method is includes at least one of the following steps: i) conducting the interfacial polymerization in the presence of a monomer comprising at least one phosphorous-containing functional group or salt thereof and an at least one amine-reactive functional group; and/or ii) applying such a monomer to the thin film polyamide layer.

Abstract: A method for making a composite polyamide membrane comprising a porous support and a thin film polyamide layer, wherein the method includes the steps of applying a polar solution comprising a polyfunctional amine monomer and a non-polar solution comprising a polyfunctional acyl halide monomer to a surface of a porous support and interfacially polymerizing the monomers to form a thin film polyamide layer. The method is characterized by including a substituted benzamide monomer within the non-polar solution.

Abstract: A method for making a composite polyamide membrane including the steps of applying a polyfunctional amine monomer and polyfunctional acyl halide monomer to a surface of the porous support and interfacially polymerizing the monomers to form a thin film polyamide layer, wherein the method is includes at least one of the following steps: i) conducting the interfacial polymerization in the presence of a subject monomer comprising at least one carboxylic acid group linked to an aromatic moiety and wherein the aromatic moiety is further substituted with at least one of an acyl halide or anhydride functional group and ii) applying the subject monomer to the thin film polyamide layer. The invention includes many additional embodiments.

Abstract: A method for making a composite polyamide membrane including a porous support and a thin film polyamide layer, wherein the method includes the step of applying a polyfunctional amine monomer and a tetraacyl acyl halide monomer represented by Formula (I) to a surface of the porous support and interfacially polymerizing the monomers to form a thin film polyamide layer; wherein A is selected from: oxygen (—O—); carbon (—C—); silicon (—Si—); each of which may be unsubstituted or substituted, e.g. with alkyl groups of 1-4 carbon atoms; or a carbonyl group (—C(O)—), X is the same or different and is selected from a halogen, and Y is selected from halogen and hydroxide.

Abstract: A method for making a composite polyamide membrane including the steps of applying a polyfunctional amine monomer and polyfunctional acyl halide monomer to a surface of the porous support and interfacially polymerizing the monomers to form a thin film polyamide layer, wherein the method is includes at least one of the following steps: i) conducting the interfacial polymerization in the presence of a subject monomer comprising at least one carboxylic acid group linked to an aromatic moiety and wherein the aromatic moiety is further substituted with at least one of an acyl halide or anhydride functional group and ii) applying the subject monomer to the thin film polyamide layer. The invention includes many additional embodiments.

Abstract: A method for making a composite polyamide membrane comprising the steps of applying a polyfunctional amine monomer and polyfunctional acyl halide monomer to a surface of the porous support and interfacially polymerizing the monomers to form a thin film polyamide layer, wherein the method is includes at least one of the following steps: i) conducting the interfacial polymerization in the presence of a monomer comprising at least one phosphorous-containing functional group or salt thereof and an at least one amine-reactive functional group; and/or ii) applying such a monomer to the thin film polyamide layer.