Abstract: A polarity-specific, multi-route delivery system for dietary supplement bioactives with each active pre-mapped to an optimized carrier tailored for oral, transdermal, or topical delivery. A unified formulation stability framework incorporates antioxidants, photoprotectants, oxygen scavengers, and nitrogen-flushed packaging, ensuring integrity under ICH Q1A(R2) conditions. The system supports modular formulations combining esterified DHEA analogs with adaptogens, minerals, amino acids, polyphenols, fatty acids, and vitamins, including coordinated oral-dermal or oral-transdermal regimens. Embodiments demonstrate enhanced nutrient bioavailability, reduced dosing frequency, and multi-phasic nutritional support for anabolic, metabolic, cognitive, cardiovascular, and healthy aging outcomes.

Abstract: A method of forming a DHEA derivative supplement including adaptogens, modified stilbenoids complex, non-esterified omega-3 fatty acids, essential amino acids, HMB free acid, vitamins, L-arginine, creatine, green tea extracts, and chelated minerals, in a multi-bioavailability delivery system, based on the nature of the constituents, formed as an encapsulated micronized material having a phytosomal delivery system which reduces supplements dosage while increasing active nutrients efficacy and bioavailability by providing a targeted delivery system for nutritional effects.

Abstract: A polarity-specific, multi-route delivery system for dietary supplement bioactives with each active pre-mapped to an optimized carrier tailored for oral, transdermal, or topical delivery. A unified formulation stability framework incorporates antioxidants, photoprotectants, oxygen scavengers, and nitrogen-flushed packaging, ensuring integrity under ICH Q1A(R2) conditions. The system supports modular formulations combining esterified DHEA analogs with adaptogens, minerals, amino acids, polyphenols, fatty acids, and vitamins, including coordinated oral-dermal or oral-transdermal regimens. Embodiments demonstrate enhanced nutrient bioavailability, reduced dosing frequency, and multi-phasic nutritional support for anabolic, metabolic, cognitive, cardiovascular, and healthy aging outcomes.

Abstract: A method of forming a DHEA derivative supplement including adaptogens, modified stilbenoids complex, non-esterified omega-3 fatty acids, essential amino acids, HMB free acid, vitamins, L-arginine, creatine, green tea extracts, and chelated minerals, in a multi-bioavailability delivery system, based on the nature of the constituents, formed as an encapsulated micronized material having a phytosomal delivery system which reduces supplements dosage while increasing active nutrients efficacy and bioavailability by providing a targeted delivery system for nutritional effects.