Patents by Inventor Amanda C. Engler

Amanda C. Engler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Poly(Propargyl-L-Glutamate) and Derivatives Thereof
    Publication number: 20110097419
    Abstract: A process of the present invention is directed toward conducting highly selective, high yield post-polymerization reactions on polypeptides to prepare functionalized polypeptides. In certain embodiments, the polypeptides can be prepared by ring opening polymerization of N-carboxyanhydrides. In certain embodiments, the post-polymerization reaction is a “click chemistry” reaction. In certain embodiment, the “click chemistry” reaction is a triazole-forming reaction involving an alkyne on the polypeptide and an azide.
    Type: Application
    Filed: October 28, 2009
    Publication date: April 28, 2011
    Applicant: Massachusetts Institute of Technology
    Inventors: Paula T. Hammond, Amanda C. Engler, Hyung-il Lee