Patents by Inventor Amanda Guth

Amanda Guth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BETA-ALETHINE, IMMUNE MODULATORS, AND USES THEREOF
    Publication number: 20240041802
    Abstract: The present disclosure provides methods, kits, and compositions comprising ?-alethine and one or more immune modulators and methods to determine when they are advantageous. Particular applications include the use of ?-alethine and one or more immune modulators in the treatment of cancer.
    Type: Application
    Filed: June 5, 2023
    Publication date: February 8, 2024
    Inventors: Floyd TAUB, Amanda Guth
  • Beta-alethine, immune modulators, and uses thereof
    Patent number: 11672771
    Abstract: The present disclosure provides methods, kits, and compositions comprising ?-alethine and one or more immune modulators and methods to determine when they are advantageous. Particular applications include the use of ?-alethine and one or more immune modulators in the treatment of cancer.
    Type: Grant
    Filed: November 3, 2017
    Date of Patent: June 13, 2023
    Assignees: AxImmune, Inc., Colorado State University Research Foundation
    Inventors: Floyd Taub, Amanda Guth
  • CANCER VACCINE COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20210000936
    Abstract: The disclosure provides a cancer vaccine composition comprising inactivated cancer cells and an adjuvant, wherein the inactivated cancer cells are incapable of replication. Also provided is a method for producing a cancer vaccine composition, the method comprising contacting cancer cells with light (e.g., UV light) in the presence of a photosensitizer (e.g., riboflavin).
    Type: Application
    Filed: March 21, 2019
    Publication date: January 7, 2021
    Inventors: Terry OPGENORTH, Amanda GUTH, Raymond GOODRICH
  • BETA-ALETHINE, IMMUNE MODULATORS, AND USES THEREOF
    Publication number: 20200069616
    Abstract: The present disclosure provides methods, kits, and compositions comprising ?-alethine and one or more immune modulators and methods to determine when they are advantageous. Particular applications include the use of ?-alethine and one or more immune modulators in the treatment of cancer.
    Type: Application
    Filed: November 3, 2017
    Publication date: March 5, 2020
    Inventors: Floyd TAUB, Amanda GUTH
  • Methods and compositions for enhancing an immune response, blocking monocyte migration, amplifying vaccine immunity and inhibiting tumor growth and metastasis
    Patent number: 10206983
    Abstract: Provided are methods of enhancing an immune response and methods for reducing the recruitment of monocytes to a lymph node by administering to an individual an angiotensin II receptor blocker or a compound of Formula (I) in conjunction with an antigen. The invention also provides relate methods for amplifying vaccine immunity by administering to an individual an angiotensin II receptor blocker or a compound of Formula (I) in conjunction with an vaccine. The invention also provides related methods of inhibiting tumor growth and metastasis by administering to an individual with cancer an angiotensin II receptor blocker or a compound of Formula (I) in conjunction with an anti-tumor preparation. In addition, related compositions comprising an ARB or a compound of Formula (I) and an antigen, vaccine, or anti-tumor preparation are provided.
    Type: Grant
    Filed: January 6, 2017
    Date of Patent: February 19, 2019
    Assignee: COLORADO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventors: Steven W. Dow, Daniel P. Regan, Amanda Guth, Leah Mitchell
  • METHODS AND COMPOSITIONS FOR ENHANCING AN IMMUNE RESPONSE, BLOCKING MONOCYTE MIGRATION, AMPLIFYING VACCINE IMMUNITY AND INHIBITING TUMOR GROWTH AND METASTASIS
    Publication number: 20170348400
    Abstract: Provided are methods of enhancing an immune response and methods for reducing the recruitment of monocytes to a lymph node by administering to an individual an angiotensin II receptor blocker or a compound of Formula (I) in conjunction with an antigen. The invention also provides relate methods for amplifying vaccine immunity by administering to an individual an angiotensin II receptor blocker or a compound of Formula (I) in conjunction with an vaccine. The invention also provides related methods of inhibiting tumor growth and metastasis by administering to an individual with cancer an angiotensin II receptor blocker or a compound of Formula (I) in conjunction with an anti-tumor preparation. In addition, related compositions comprising an ARB or a compound of Formula (I) and an antigen, vaccine, or anti-tumor preparation are provided.
    Type: Application
    Filed: January 6, 2017
    Publication date: December 7, 2017
    Inventors: Steven W. Dow, Daniel P. Regan, Amanda Guth, Leah Mitchell