Patents by Inventor Amanda M. Tafoya

Amanda M. Tafoya has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method to enhance immunogenicity of live typhoid vaccines and carriers
    Patent number: 11254713
    Abstract: In certain embodiments, a recombinant attenuated derivative of a pathogenic Salmonella enterica serovar typhi cell is provided, (a) wherein one or more genes encoding subunits of a stg operon (Salmonella typhi ?stg) are inactivated or deleted resulting in a decrease of Stg adhesin/fimbriae production as compared to genes encoding a wild-type Stg operon (stgABCC?D), and/or (b) the cell comprises a nucleic acid encoding at least one of a gene encoding a subunit of a long polar fimbriae (Lpf) of S. enterica serovar Typhimurium protein. In certain embodiments, vaccines and compositions, and methods of use of the recombinant attenuated derivative of a pathogenic Salmonella enterica serovar typhi cell are provided.
    Type: Grant
    Filed: May 1, 2018
    Date of Patent: February 22, 2022
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Kenneth Roland, Amanda M. Tafoya
  • METHOD TO ENHANCE IMMUNOGENICITY OF LIVE TYPHOID VACCINES AND CARRIERS
    Publication number: 20180312550
    Abstract: In certain embodiments, the present invention provides a recombinant Salmonella enterica serovar Typhi cell, vaccines and compositions, and methods of use thereof.
    Type: Application
    Filed: May 1, 2018
    Publication date: November 1, 2018
    Inventors: Kenneth Roland, Amanda M. Tafoya