Abstract: A gaseous nitric oxide (NO) sensor having a working electrode configured such to induce NO molecules proximate the working electrode to undergo an electrochemical oxidation reaction. The electrochemical oxidation reaction transfers electrons from the NO molecules to the working electrode, creating a measurable current corresponding to the NO concentration within the fluid sample. An external membrane can be deposited onto the working electrode to separate the fluid sample from the working electrode. The external membrane can comprise an ionomer selectively permitting diffusion of NO molecules through the external membrane from the fluid sample to the working electrode. In an example, the fluid sample can be heated to a predetermined temperature to facilitate dissociation of NO from its hemoglobin bonded forms proximate the external membrane.

Abstract: Apparatus and methods in accordance with one or more preferred embodiments of the present invention are used to measure nitric oxide in a fluid, and each includes a sample injection port; a pump; a measurement chamber; an electromagnetic radiation source; one or controls and user interfaces; and a cartridge. The cartridge includes a sample chamber; an electromagnetic radiation and heat chamber; and a gas permeable membrane. The cartridge preferably is single-use and disposable. Further apparatus and methods in accordance with other alternative embodiments, and additional inventive aspects and features, are disclosed related to measuring nitric oxide in a fluid.

Abstract: An exemplary apparatus for measuring nitric oxide in a fluid includes a sample injection port; a pump and reservoir; a valve; a measurement chamber; an electromagnetic radiation source; controls and user interface; and a cartridge. The cartridge includes a sample chamber a mix chamber; a sample degassing chamber; and a planar reaction chamber. The cartridge preferably is single-use and disposable. Furthermore, additional inventive aspects and features are disclosed related to measuring nitric oxide in a fluid.

Abstract: An exemplary apparatus for measuring nitric oxide in a fluid includes a sample injection port; a pump and reservoir; a valve; a measurement chamber; an electromagnetic radiation source; controls and user interface; and a cartridge. The cartridge includes a sample chamber a mix chamber; a sample degassing chamber; and a planar reaction chamber. The cartridge preferably is single-use and disposable. Furthermore, additional inventive aspects and features are disclosed related to measuring nitric oxide in a fluid.

Abstract: Apparatus and methods in accordance with one or more preferred embodiments of the present invention are used to measure nitric oxide in a fluid, and each includes a sample injection port; a pump; a measurement chamber; an electromagnetic radiation source; one or controls and user interfaces; and a cartridge. The cartridge includes a sample chamber; an electromagnetic radiation and heat chamber; and a gas permeable membrane. The cartridge preferably is single-use and disposable. Further apparatus and methods in accordance with other alternative embodiments, and additional inventive aspects and features, are disclosed related to measuring nitric oxide in a fluid.