Patents by Inventor Amanda NASH

Amanda NASH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMPLANTABLE CONSTRUCTS FOR MODULATING AN IMMUNE RESPONSE
    Publication number: 20240041755
    Abstract: The present disclosure relates to implantable constructs and related compositions comprising a plurality of cells producing antigens and/or immune effector molecules.
    Type: Application
    Filed: December 17, 2021
    Publication date: February 8, 2024
    Applicant: William Marsh Rice University
    Inventors: Omid VEISEH, Amanda NASH, Boram KIM, Damon BERMAN, Lauren CHENG, David ZHANG
  • ENCAPSULATED CELLS EXPRESSING IL-12 AND USES THEREOF
    Publication number: 20240041939
    Abstract: The present disclosure relates to implantable constructs (encapsulated cells) designed to deliver therapeutic reagents, such as IL-12 and/or IL-12 and methods of using the same to treat conditions, such as cancer.
    Type: Application
    Filed: December 16, 2022
    Publication date: February 8, 2024
    Applicant: William Marsh Rice University
    Inventors: Omid VEISEH, Amanda NASH, Samira AGHLARA-FOTOVAT
  • ENCAPSULATED CELLS EXPRESSING IL-2 AND USES THEREOF
    Publication number: 20230265149
    Abstract: The present disclosure relates to implantable constructs (encapsulated cells) designed to deliver antigenic therapeutic reagents, such as IL-2.
    Type: Application
    Filed: October 19, 2022
    Publication date: August 24, 2023
    Applicant: William Marsh Rice University
    Inventors: Omid VEISEH, David ZHANG, Sudip MUKHERJEE, Maria RUOCCO, Michael DOERFERT, Amanda NASH, Samira AGHLARA-FOTOVAT
  • METHODS FOR IMPROVED DELIVERY OF THERAPEUTIC AGENTS
    Publication number: 20230210908
    Abstract: The present disclosure provides expression constructs designed to provide for expression of therapeutic proteins from engineered cells. The engineered cells may be encapsulated into implantable elements that allow for the therapeutic protein to be released into from the capsule while protecting the cell from the immune system of a patient into which the capsule is implanted.
    Type: Application
    Filed: February 11, 2021
    Publication date: July 6, 2023
    Applicant: William Marsh Rice University
    Inventors: Omid VEISEH, Amanda NASH, Bhagyashree Kishor BACHHAV, Carlos Alberto ORIGEL MARMOLEJO, Damon BERMAN, Christian SCHREIB, Laura SEGATORI, Alen TRUBELJA, Oleg A. IGOSHIN, Andrew D. HECHT
  • IMPLANTABLE CONSTRUCTS AND USES THEREOF
    Publication number: 20220313599
    Abstract: The present disclosure relates to implantable constructs designed to deliver antigenic therapeutic reagents to a subject while providing protection from host immune responses. In certain aspects, the constructs are designed to degrade over time or upon a particular signal, thereby providing control of the length of time the therapeutic agent is delivered to the subject.
    Type: Application
    Filed: August 7, 2020
    Publication date: October 6, 2022
    Applicant: William Marsh Rice University
    Inventors: Omid VEISEH, Amanda NASH, Maria Isabel JARVIS-RUOCCO, Sudip MUKHERJEE, Michael David DOERFERT, Samira AGHLARA-FOTOVAT, David Yu ZHANG