Patents by Inventor Amanda Peters

Amanda Peters has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200247765
    Abstract: The present disclosure relates to certain (2S)—N-[(1S)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamide compounds (including pharmaceutically acceptable salts thereof), that inhibit dipeptidyl peptidase 1 (DPP1) activity, to their utility in treating and/or preventing clinical conditions including respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), to their use in therapy, to pharmaceutical compositions containing them and to processes for preparing such compounds.
    Type: Application
    Filed: April 22, 2020
    Publication date: August 6, 2020
    Inventors: Hans Roland LONN, Stephen CONNOLLY, Steven SWALLOW, Staffan PO KARLSSON, Carl-Johan AURELL, John Fritiof PONTÉN, Kevin James DOYLE, Amanda Jane VAN DE POËL, Graham Peter JONES, David Wyn WATSON, Jaqueline Anne MACRITCHIE, Nicholas John PALMER
  • Patent number: 10669245
    Abstract: The present disclosure relates to certain (2S)—N-[(1S)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamide compounds (including pharmaceutically acceptable salts thereof), that inhibit dipeptidyl peptidase 1 (DPP1) activity, to their utility in treating and/or preventing clinical conditions including respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), to their use in therapy, to pharmaceutical compositions containing them and to processes for preparing such compounds.
    Type: Grant
    Filed: March 19, 2019
    Date of Patent: June 2, 2020
    Assignee: ASTRAZENECA AB
    Inventors: Hans Roland Lonn, Stephen Connolly, Steven Swallow, Staffan Po Karlsson, Carl-Johan Aurell, John Fritiof Pontén, Kevin James Doyle, Amanda Jane Van De Poël, Graham Peter Jones, David Wyn Watson, Jaqueline Anne Macritchie, Nicholas John Palmer
  • Publication number: 20200017455
    Abstract: The present disclosure relates to certain (2S)—N-[(1S)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamide compounds (including pharmaceutically acceptable salts thereof), that inhibit dipeptidyl peptidase 1 (DPP1) activity, to their utility in treating and/or preventing clinical conditions including respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), to their use in therapy, to pharmaceutical compositions containing them and to processes for preparing such compounds.
    Type: Application
    Filed: March 19, 2019
    Publication date: January 16, 2020
    Inventors: Hans Roland LONN, Stephen CONNOLLY, Steven SWALLOW, Staffan PO KARLSSON, Carl-Johan AURELL, John Fritiof PONTÉN, Kevin James DOYLE, Amanda Jane VAN DE POËL, Graham Peter JONES, David Wyn WATSON, Jaqueline Anne MACRITCHIE, Nicholas John PALMER
  • Publication number: 20190269930
    Abstract: In embodiments, a Wearable Cardiac Defibrillator (WCD) system is configured to be worn by an ambulatory patient. The WCD system includes a main user interface (UI) output device that can output an image, sound or vibration as a main message about a condition of the patient or the WCD system. The patient may further carry a peripheral device that can also output an image, sound or vibration as a peripheral message about the condition. The peripheral message may mirror the main message at least in part, amplify it, and so on. The availability of the peripheral message provides the patient with the opportunity to better perceive the main message, and the flexibility to receive and react to it discreetly, learn more about the condition, and so on.
    Type: Application
    Filed: February 22, 2019
    Publication date: September 5, 2019
    Inventors: Zoie Engman, Aaron Piazza, Christoffer Peter Hart Hansen, David P. Finch, Laura M. Gustavson, Erik L. Schneider, Erick Roane, Amanda K. Hall
  • Publication number: 20190186662
    Abstract: A system includes a first body of a fluid-handling component and a second body of a fluid-handling component. The system also includes a fastener configured to couple the first body to the second body, and an annular sleeve configured to surround a portion of the fastener that is positioned at an interface between the first body and the second body when the first body and the second body are coupled to one another.
    Type: Application
    Filed: December 20, 2017
    Publication date: June 20, 2019
    Applicant: Cameron International Corporation
    Inventors: Mark Anthony McGilvray, JR., Kevin Peter Minnock, Amanda Diane Smith, James Daniel Ekdahl, Loc G. Hoang
  • Patent number: 10287258
    Abstract: The present disclosure relates to certain (2S)-N-[(1S)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamide compounds (including pharmaceutically acceptable salts thereof), that inhibit dipeptidyl peptidase 1 (DPP1) activity, to their utility in treating and/or preventing clinical conditions including respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), to their use in therapy, to pharmaceutical compositions containing them and to processes for preparing such compounds.
    Type: Grant
    Filed: September 19, 2017
    Date of Patent: May 14, 2019
    Assignee: ASTRAZENECA AB
    Inventors: Hans Roland Lonn, Stephen Connolly, Steven Swallow, Staffan Po Karlsson, Carl-Johan Aurell, John Fritiof Pontén, Kevin James Doyle, Amanda Jane Van De Poël, Graham Peter Jones, David Wyn Watson, Jaqueline Anne Macritchie, Nicholas John Palmer
  • Publication number: 20190134379
    Abstract: A supportive clothing article for a wearable cardioverter defibrillator (WCD), including a belt, the belt including a first end with a first portion of a fastener and a second end with a second portion of the fastener, wherein the belt is structured to fasten around the torso of patient below the chest area of the patient, the belt including a first conductive mesh portion adjacent the first end of the belt or the second end of the belt, two straps, a back portion extending from the belt at an intermediary position on the belt to each of the two straps, the back portion including a conductive mesh, a first support receptacle attached to and extending from the belt and attachable to one of the two straps, and a second support receptacle attached to and extending from the belt and attachable to the other of the two straps.
    Type: Application
    Filed: February 5, 2018
    Publication date: May 9, 2019
    Inventors: Laura Marie Gustavson, Kerstin Dorst, Angela M. Stewart, Pamela Breske, Amanda K. Hall, Garrett McCann Kotlarchik, Dallas Eugene Meeker, Daniel James Finney, Eduard Deml, Robert Reuben Buchanan, David Peter Finch, Phillip Dewey Foshee, Douglas Keith Medema, Kenneth F. Cowan
  • Patent number: 10268741
    Abstract: Embodiments of the invention are described being used to distribute a database across a plurality of compute nodes of a parallel computing system. That is, a method is described for creating a fully in-memory database on the parallel computing system. Further, data compression techniques are described being used to increase the performance of the in-memory database by compressing some portions of the database to fit within a single node or a logically or physically related group of nodes.
    Type: Grant
    Filed: August 3, 2007
    Date of Patent: April 23, 2019
    Assignee: International Business Machines Corporation
    Inventors: Eric Lawrence Barsness, Amanda Peters, John Matthew Santosuosso
  • Patent number: 9514023
    Abstract: Embodiments of the invention provide for controlling message flow across a parallel computer system having multiple compute nodes by selectively grouping compute nodes of such a system into node pools and assigning message flow control policies to nodes in the node pools. The message flow control policies specify logging and/or tracing activities to be performed by instances of applications running on nodes assigned to the node pools. As the application is executed, logging and/or tracing messages are generated on the compute nodes according to message flow control policies assigned to the nodes. Optionally, the message flow is analyzed, the message flow control policies are adjusted, and duplicate messages are eliminated.
    Type: Grant
    Filed: June 24, 2008
    Date of Patent: December 6, 2016
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Eric L. Barsness, David L. Darrington, Amanda Peters, John M. Santosuosso
  • Patent number: 9268614
    Abstract: Methods, systems, and products are disclosed for configuring an application for execution on a parallel computer that include: booting up a first subset of a plurality of nodes in a serial processing mode; booting up a second subset of the plurality of nodes in a parallel processing mode; profiling, prior to application deployment on the parallel computer, the application to identify the serial segments and the parallel segments of the application; and deploying the application for execution on the parallel computer in dependence upon the profile of the application and proximity within the data communications network of the nodes in the first subset relative to the nodes in the second subset.
    Type: Grant
    Filed: March 22, 2012
    Date of Patent: February 23, 2016
    Assignee: International Business Machines Corporation
    Inventors: Eric L. Barsness, David L. Darrington, Amanda Peters, John M. Santosuosso
  • Patent number: 9225545
    Abstract: Determining a path for network traffic between a source compute node and a destination compute node in a parallel computer including identifying a group of compute nodes, the group of compute nodes having topological network locations included in a predefined topological shape; selecting, from the predefined topological shape, in dependence upon a global contention counter stored on the source compute node, a path on which to send a data communications message from the source compute node to the destination compute node; and sending, by the messaging module of the source compute node, the data communications message along the selected path for network traffic between the source and destination compute nodes.
    Type: Grant
    Filed: April 1, 2008
    Date of Patent: December 29, 2015
    Assignee: International Business Machines Corporation
    Inventors: Charles J. Archer, Amanda Peters, Brian E. Smith, Brent A. Swartz
  • Patent number: 9167034
    Abstract: A method and apparatus performs peer-to-peer file transfers on a High Performance Computing (HPC) cluster such as a Beowulf cluster. A peer-to-peer file tracker (PPFT) allows operating system, application and data files to be moved from a pre-loaded node to another node of the HPC cluster. A peer-to-peer (PTP) client is loaded into the nodes to facilitate PTP file transfers to reduce loading on networks, network switches and file servers to reduce the time needed to load the nodes with these files to increase overall efficiency of the multi-node computing system. The selection of the nodes participating in file transfers can be based on network topology, network utilization, job status and predicted network/computer utilization. This selection can be dynamic, changing during the file transfers as resource conditions change. The policies used to choose resources can be configured by an administrator.
    Type: Grant
    Filed: November 12, 2007
    Date of Patent: October 20, 2015
    Assignee: International Business Machines Corporation
    Inventors: Eric Lawrence Barsness, David L. Darrington, Amanda Peters, John Matthew Santosuosso
  • Patent number: 9025607
    Abstract: A system and method to reduce the number of data transmissions between nodes in a network is described. In one embodiment, a system and method for reducing the amount of ACK and NAK traffic in a network is described.
    Type: Grant
    Filed: November 5, 2012
    Date of Patent: May 5, 2015
    Assignee: Massachusetts Institute of Technology
    Inventors: Linda M. Zeger, Muriel Medard, Amanda Peters
  • Patent number: 9009350
    Abstract: Determining a path for network traffic between a source compute node and a destination compute node in a parallel computer including: beginning with an identified group of compute nodes that includes the source compute node and iteratively until an identified group of compute nodes includes the destination compute node: identifying a group of compute nodes, the group of compute nodes having topological network locations included in a predefined topological shape; selecting a path for network traffic between compute nodes having topological network locations included in the predefined topological shape, and when an identified group of compute nodes includes the destination compute node: selecting a final path for network traffic; and sending a data communications message along the path for network traffic between the source compute node and the destination compute node, the path including, in order of selection, the selected paths and the selected final path.
    Type: Grant
    Filed: April 1, 2008
    Date of Patent: April 14, 2015
    Assignee: International Business Machines Corporation
    Inventors: Charles J. Archer, Amanda Peters, Brian E. Smith, Brent A. Swartz
  • Patent number: 8892558
    Abstract: A method and apparatus loads data to an in-memory database across multiple nodes in a parallel computing system. A database loader uses SQL flags, historical information gained from monitoring prior query execution times and patterns, and node and network configuration to determine how to effectively cluster data attributes across multiple nodes. The database loader may also allow a system administrator to force placement of database structures in particular nodes.
    Type: Grant
    Filed: September 26, 2007
    Date of Patent: November 18, 2014
    Assignee: International Business Machines Corporation
    Inventors: Eric Lawrence Barsness, David L. Darrington, Amanda Peters, John Matthew Santosuosso
  • Patent number: 8874722
    Abstract: An interactive tool is disclosed for visualizing performance data in real-time to enable adaptive performance optimization for an application running on a massively parallel computer system. The interactive tool may be used to visualize network congestion (and other) performance counters for an application as it runs on the parallel system in real-time. Further, a developer may use the interactive tool to experiment with various tuning options and optimization approaches on-the-fly.
    Type: Grant
    Filed: September 28, 2007
    Date of Patent: October 28, 2014
    Assignee: International Business Machines Corporation
    Inventors: Thomas Michael Gooding, David Lee Hermsmeier, Roy Glenn Musselman, Amanda Peters, Kurt Walter Pinnow, Brent Allen Swartz
  • Patent number: 8868623
    Abstract: Embodiments of the invention enhance a garbage collection process running on a parallel system or distributed computing environment. Using a garbage collector in such an environment allows a more in-depth analysis to be performed than is possible on other systems. This is because the number of compute nodes present in many parallel systems, and the connections between them, allows the overhead of doing advanced analysis to be spread across the nodes and the results of that analysis to be shared among the nodes.
    Type: Grant
    Filed: October 30, 2007
    Date of Patent: October 21, 2014
    Assignee: International Business Machines Corporation
    Inventors: Eric Lawrence Barsness, David L. Darrington, Amanda Peters, John Matthew Santosuosso
  • Patent number: 8812818
    Abstract: A method and apparatus creates and manages persistent memory (PM) in a multi-node computing system. A PM Manager in the service node creates and manages pools of nodes with various sizes of PM. A node manager uses the pools of nodes to load applications to the nodes according to the size of the available PM. The PM Manager can dynamically adjust the size of the PM according to the needs of the applications based on historical use or as determined by a system administrator. The PM Manager works with an operating system kernel on the nodes to provide persistent memory for application data and system metadata. The PM Manager uses the persistent memory to load applications to preserve data from one application to the next. Also, the data preserved in persistent memory may be system metadata such as file system data that will be available to subsequent applications.
    Type: Grant
    Filed: February 14, 2012
    Date of Patent: August 19, 2014
    Assignee: International Business Machines Corporation
    Inventors: Eric Lawrence Barsness, David L. Darrington, Patrick Joseph McCarthy, Amanda Peters, John Matthew Santosuosso
  • Patent number: 8671418
    Abstract: Embodiments of the invention provide techniques that improve resource management on a massively parallel computing system having a plurality of hybrid compute nodes. For example, a job scheduler may be provided which determines a library to link to an application based on system and user requirements. In one embodiment, the libraries may provide optimizations for job execution time, and also provide optimizations directed towards a specific processor architecture. Once the library is determined, the job scheduler may configure the environment of the application so that the application links with the optimized library during run-time. Doing so may improve overall system performance of the massively parallel computing system.
    Type: Grant
    Filed: February 10, 2009
    Date of Patent: March 11, 2014
    Assignee: International Business Machines Corporation
    Inventors: Eric L. Barsness, David L. Darrington, Amanda Peters, John M. Santosuosso
  • Patent number: 8650205
    Abstract: Techniques are disclosed for invoking an analysis routine running on a parallel computer system to analyze query results. A query generated using a query builder application for execution against a database to produce query results. Embodiments receive a selection of one of a plurality of analysis routines to apply to the query results. A command and the query results are transmitted to a compute node of a parallel computer system using an established network connection. Embodiments invoke the selected analysis routine on the parallel computing system using the translated command and the query results to produce analysis routine results. The analysis routine results are merged with the query results to produce merged results, and the merged results are output for display.
    Type: Grant
    Filed: December 11, 2012
    Date of Patent: February 11, 2014
    Assignee: International Business Machines Corporation
    Inventors: Richard D. Dettinger, Mark G. Megerian, Amanda Peters