Patents by Inventor Amar N. Kar

Amar N. Kar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Targeting G3BP aggregation to prevent neurodegeneration
    Patent number: 11851462
    Abstract: Testing peptides in in vitro models of neurodegenerative disorders such as Parkinson's disease, Alzheimer's disease, Frontotemporal dementia, Amyotrophic lateral sclerosis, to evaluate systems and methods of treatment therefore.
    Type: Grant
    Filed: May 22, 2020
    Date of Patent: December 26, 2023
    Assignee: University of South Carolina
    Inventors: Amar N. Kar, Pabitra Sahoo, Jeffery Twiss, Sean McGill
  • TARGETING G3BP AGGREGATION TO PREVENT NEURODEGENERATION
    Publication number: 20230190887
    Abstract: Testing peptides in in vitro models of neurodegenerative disorders such as Parkinson's disease, Alzheimer's disease, Frontotemporal dementia, Amyotrophic lateral sclerosis, to evaluate systems and methods of treatment therefore.
    Type: Application
    Filed: November 18, 2022
    Publication date: June 22, 2023
    Applicants: University of South Carolina, Ramot at Tel-Aviv University Ltd., Tel HaShomer Medical Research Infrastructure and Services Ltd.
    Inventors: Amar N. Kar, Pabitra Sahoo, Jeffery Twiss, Sean McGill, Eran Perlson, Topaz Altman, Ariel Razvan Ionescu, Tal Gradus-Pery, Amir Dori
  • Acetylation of Miro1
    Publication number: 20210330756
    Abstract: Deacetylation of rat Miro1 on Lysine 105 attenuates axon growth on non-permissive substrates by making mitochondria more sensitive to Ca levels, depolarizing mitochondrial membranes and blocking mitochondrial transport; the current disclosure provides an antibody that specifically recognizes the lysine 105 acetylated and not the deacetylated Miro1 protein.
    Type: Application
    Filed: March 1, 2021
    Publication date: October 28, 2021
    Applicant: University of South Carolina
    Inventors: Jeffery L. Twiss, Amar N. Kar
  • TARGETING G3BP AGGREGATION TO PREVENT NEURODEGENERATION
    Publication number: 20210024591
    Abstract: Testing peptides in in vitro models of neurodegenerative disorders such as Parkinson's disease, Alzheimer's disease, Frontotemporal dementia, Amyotrophic lateral sclerosis, to evaluate systems and methods of treatment therefore.
    Type: Application
    Filed: May 22, 2020
    Publication date: January 28, 2021
    Applicant: University of South Carolina
    Inventors: Amar N. Kar, Pabitra Sahoo, Jeffery Twiss, Sean McGill