Patents by Inventor Amar Sahay

Amar Sahay has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MOLECULAR RE-ENGINEERING OF EXCITATION-INHIBITION BALANCE IN MEMORY CIRCUITS
    Publication number: 20190241894
    Abstract: Memory-regulating agents and methods that target actin binding LIM protein family, member 3 (ABLIM3).
    Type: Application
    Filed: April 19, 2019
    Publication date: August 8, 2019
    Inventors: Amar Sahay, Nannan Guo
  • Molecular re-engineering of excitation-inhibition balance in memory circuits
    Patent number: 10287580
    Abstract: Disclosed are memory-regulating agents and methods that target actin binding LIM protein family, member 3 (ABLIM3). Specifically, the disclosure provides methods of inhibiting Ablim3 using inhibitory nucleic acids that target the Ablim3 gene or mRNA to improve memory in subjects with memory dysfunction associated with Alzheimer's Disease (AD), normal aging, or posttraumatic stress disorder (PTSD). Further disclosed is a cell-based assay that can be used to screen for small molecule regulators of Ablim3 function.
    Type: Grant
    Filed: March 13, 2015
    Date of Patent: May 14, 2019
    Assignee: The General Hospital Corporation
    Inventors: Amar Sahay, Nannan Guo
  • MOLECULAR RE-ENGINEERING OF EXCITATION-INHIBITION BALANCE IN MEMORY CIRCUITS
    Publication number: 20160376588
    Abstract: Disclosed are memory-regulating agents and methods that target actin binding LIM protein family, member 3 (ABLIM3). Specifically, the disclosure provides methods of inhibiting Ablim3 using inhibitory nucleic acids that target the Ablim3 gene or mRNA to improve memory in subjects with memory dysfunction associated with Alzheimer's Disease (AD), normal aging, or posttraumatic stress disorder (PTSD). Further disclosed is a cell-based assay that can be used to screen for small molecule regulat ors of Ablim3 function.
    Type: Application
    Filed: March 13, 2015
    Publication date: December 29, 2016
    Inventors: Amar Sahay, Nannan Guo