Patents by Inventor Amarendra Mikkilineni

Amarendra Mikkilineni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bicyclic heterocycles as cannabinoind-1 receptor modulators
    Patent number: 7317012
    Abstract: The present application describes compounds according to Formula I, pharmaceutical compositions comprising at least one compound according to Formula I and optionally one or more additional therapeutic agents and methods of treatment using the compounds according to Formulas I both alone and in combination with one or more additional therapeutic agents. The compounds have the following general formulas: including all prodrugs, solvates, pharmaceutically acceptable salts and stereoisomers, wherein B, R1, R2, R3 and x are described herein.
    Type: Grant
    Filed: June 16, 2006
    Date of Patent: January 8, 2008
    Assignee: Bristol-Myers Squibb Company
    Inventors: Chongqing Sun, Yanting Huang, Doree F. Sitkoff, Guixue Yu, Amarendra Mikkilineni, William R. Ewing
  • Bicyclic heterocycles as cannabinoind-1 receptor modulators
    Publication number: 20060287322
    Abstract: The present application describes compounds according to Formula I, pharmaceutical compositions comprising at least one compound according to Formula I and optionally one or more additional therapeutic agents and methods of treatment using the compounds according to Formulas I both alone and in combination with one or more additional therapeutic agents. The compounds have the following general formulas: including all prodrugs, solvates, pharmaceutically acceptable salts and stereoisomers, wherein B, R1, R2, R3 and x are described herein.
    Type: Application
    Filed: June 16, 2006
    Publication date: December 21, 2006
    Inventors: Chongqing Sun, Yanting Huang, Doree Sitkoff, Guixue Yu, Amarendra Mikkilineni, William Ewing
  • Triazolopyrimidine heterocycles as cannabinoid receptor modulators
    Publication number: 20060287342
    Abstract: The present application describes compounds according to Formula I, pharmaceutical compositions comprising at least one compound according to Formula I and optionally one or more additional therapeutic agents and methods of treatment using the compounds according to Formula I both alone and in combination with one or more additional therapeutic agents. The compounds have the following general formula: including all prodrugs, solvates, pharmaceutically acceptable salts and stereoisomers, wherein R1, R2, R3 and R6 are described herein.
    Type: Application
    Filed: June 19, 2006
    Publication date: December 21, 2006
    Inventors: Amarendra Mikkilineni, Natesan Murugesan, Guixue Yu
  • Triazolopyrimidine cannabinoid receptor 1 antagonists
    Publication number: 20060287341
    Abstract: The present application describes compounds according to both Formulas I and II, pharmaceutical compositions comprising at least one compound according to either Formula I or II and optionally one or more additional therapeutic agents, and methods of treatment using the compounds according to Formulas I and II both alone and in combination with one or more additional therapeutic agents. The compounds have the following general formulas: including all prodrugs, solvates, pharmaceutically acceptable salts and stereoisomers, wherein R1, R2, R3, R4 and R5 are described herein.
    Type: Application
    Filed: June 16, 2006
    Publication date: December 21, 2006
    Inventors: Gang Wu, Amarendra Mikkilineni, Philip Sher, Natesan Murugesan, Zhengxiang Gu
  • Azabicyclic heterocycles as cannabinoid receptor modulators
    Publication number: 20050171110
    Abstract: The present application describes compounds according to Formula I, pharmaceutical compositions comprising at least one compound according to Formula I and optionally one or more additional therapeutic agents and methods of treatment using the compounds according to Formula I both alone and in combination with one or more additional therapeutic agents. The compounds have the general Formula I. including all prodrugs, pharmaceutically acceptable salts and stereoisomers, R1, R2, R3, R4, R5, m and n are described herein.
    Type: Application
    Filed: December 17, 2004
    Publication date: August 4, 2005
    Inventors: Guixue Yu, William Ewing, Amarendra Mikkilineni, Annapurna Pendri, Bruce Ellsworth, Philip Sher, Samuel Gerritz, Chongqing Sun, Natesan Murugesan, Ximao Wu
  • Azabicyclic heterocycles as cannabinoid receptor modulators
    Publication number: 20050143381
    Abstract: The present application describes compounds according to Formula I, pharmaceutical compositions comprising at least one compound according to Formula I and optionally one or more additional therapeutic agents and methods of treatment using the compounds according to Formula I both alone and in combination with one or more additional therapeutic agents. The compounds have the general Formula I: including all prodrugs, pharmaceutically acceptable salts and stereoisomers, R1, R2, R3, R6, R7, m and n are described herein.
    Type: Application
    Filed: December 17, 2004
    Publication date: June 30, 2005
    Inventors: Guixue Yu, William Ewing, Amarendra Mikkilineni, Annapurna Pendri, Philip Sher, Samuel Gerritz, Bruce Ellsworth, Gang Wu, Yanting Huang, Chongqing Sun, Natesan Murugesan, Zhengxiang Gu, Ying Wang, Doree Sitkoff, Stephen Johnson, Ximao Wu
  • Phosphonooxy and carbonate derivatives of taxol
    Patent number: 5272171
    Abstract: The present invention is directed to novel taxol derivatives useful as anti-tumor agents. Also provided by this invention is pharmaceutical formulations and methods of treating mammalian tumors with the compounds of this invention.
    Type: Grant
    Filed: November 24, 1992
    Date of Patent: December 21, 1993
    Assignee: Bristol-Myers Squibb Company
    Inventors: Yasutsugu Ueda, Henry Wong, Vittorio Farina, Amarendra Mikkilineni, Dolatrai M. Vyas, Terrence Doyle