Patents by Inventor Amedeo Caflisch

Amedeo Caflisch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N6-ADENOSINE-METHYLTRANSFERASE INHIBITORS IN CANCER TREATMENT
    Publication number: 20240139189
    Abstract: The present invention relates to N6-adenosine-methyltransferase inhibitors and to dual N6-adenosine-methyltransferase E3 ligase binders in cancer treatment.
    Type: Application
    Filed: November 10, 2023
    Publication date: May 2, 2024
    Inventors: Amedeo CAFLISCH, Aymeric DOLBOIS, Danzhi HUANG, Frantisek ZALESAK
  • Anti-angiogenic compounds
    Patent number: 8765775
    Abstract: The invention relates to compounds of formula 1, tautomers and salts thereof, wherein R1, R2, R3, R4, and R5 have the meanings indicated in the specification. These compounds are receptor tyrosine kinase EphB4 inhibitors useful for the treatment of angiogenesis dependent cancers and intraocular neovascular syndromes. The invention further relates to a method termed ALTA (anchor-based library tailoring) of selecting compounds from a large compound library for screening as EphB4 inhibitors by computational procedures.
    Type: Grant
    Filed: January 23, 2009
    Date of Patent: July 1, 2014
    Assignee: Universitaet Zuerich
    Inventors: Danzhi Huang, Peter Kolb, Karine Lafleur, Cristina Nevado, Amedeo Caflisch
  • ANTI-ANGIOGENIC COMPOUNDS
    Publication number: 20110077401
    Abstract: The invention relates to compounds of formula 1, tautomers and salts thereof, wherein R1, R2, R3, R4, and R5 have the meanings indicated in the specification. These compounds are receptor tyrosine kinase EphB4 inhibitors useful for the treatment of angiogenesis dependent cancers and intraocular neovascular syndromes. The invention further relates to a method termed ALTA (anchor-based library tailoring) of selecting compounds from a large compound library for screening as EphB4 inhibitors by computational procedures.
    Type: Application
    Filed: January 23, 2009
    Publication date: March 31, 2011
    Applicant: UNIVERSITAET ZUERICH
    Inventors: Danzhi Huang, Peter Kolb, Karine Lafleur, Cristina Nevado, Amedeo Caflisch