Patents by Inventor Amedeo Columbano

Amedeo Columbano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL THYROMIMETICS WITH A BIPHENYLMETHANE SCAFFOLD AND THEIR USE
    Publication number: 20220227698
    Abstract: The invention concerns a compound of Formula (I) or a salt thereof, wherein R1 is H, (C1-C3)alkyl or CF3; R2 is H, (C1-C3)alkyl or CF3; A is CH2COOH, XCH2COOCH2CH3, XCH2COOH, XCH2CH2NH2, where X is nitrogen or oxygen atom; Ar is an aromatic fragment selected from the group consisting of (Ar1), (Ar2) and (Ar3); where R3 is H, —CH3, —CH2CH3 or CH3CO—, R4 is H or —CH3, R5 is H or —CH3, and R6 is H or —CH3. The compounds of Formula (I) can be used in the treatment of diseases modulated by thyroid hormone receptor-beta (TRb or TR?).
    Type: Application
    Filed: March 10, 2020
    Publication date: July 21, 2022
    Applicant: INTERNATIONAL SOCIETY FOR DRUG DEVELOPMENT S.R.L.
    Inventors: Guido Puricelli, Simona Rapposelli, Grazia Chiellini, Amedeo Columbano, Andrea Perra, Massimiliano Runfola, Sheraz Gul
  • USE OF GC-1 IN TRANSPLANT RELATED POPULATION
    Publication number: 20200375928
    Abstract: Methods are disclosed for the use of GC-1 (sobetirome), a prodrug thereof, or a pharmaceutically acceptable salt or prodrug thereof to increase liver regeneration and healing in liver transplant donors and recipients.
    Type: Application
    Filed: August 19, 2020
    Publication date: December 3, 2020
    Applicants: University of Pittsburgh - Of the Commonwealth System of Higher Education, Università degli Studi di Cagliari
    Inventors: Satdarshan Pal Singh Monga, Amedeo Columbano
  • Use of GC-1 in transplant related population
    Patent number: 10780069
    Abstract: Methods are disclosed for the use of GC-1 (sobetirome), a prodrug thereof, or a pharmaceutically acceptable salt or prodrug thereof to increase liver regeneration and healing in liver transplant donors and recipients.
    Type: Grant
    Filed: May 15, 2018
    Date of Patent: September 22, 2020
    Assignees: University of Pittsburgh—Of the Commonwealth System of Higher Education, Universitá degli Studi di Cagliari
    Inventors: Satdarshan Pal Singh Monga, Amedeo Columbano
  • USE OF GC-1 IN TRANSPLANT RELATED POPULATION
    Publication number: 20180333378
    Abstract: Methods are disclosed for the use of GC-1 (sobetirome), a prodrug thereof, or a pharmaceutically acceptable salt or prodrug thereof to increase liver regeneration and healing in liver transplant donors and recipients.
    Type: Application
    Filed: May 15, 2018
    Publication date: November 22, 2018
    Applicants: University of Pittsburgh - Of the Commonwealth System of Higher Education, Università degli Studi di Cagliari
    Inventors: Satdarshan Pal Singh Monga, Amedeo Columbano