Patents by Inventor Amedeo Vetere

Amedeo Vetere has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS AND METHODS FOR REGULATING INSULIN SECRETION
    Publication number: 20230142508
    Abstract: Disclosed herein are methods for inducing insulin secretion in a glucose-dependent manner and compounds for use in these methods.
    Type: Application
    Filed: November 21, 2022
    Publication date: May 11, 2023
    Applicants: The Broad Institute, Inc., The General Hospital Corporation, Instituto Carlos Slim de la Salud, A.C.
    Inventors: Sean M. Burns, Bridget K. Wagner, Amedeo Vetere
  • Compounds and methods for regulating insulin secretion
    Patent number: 11555031
    Abstract: Disclosed herein are methods for inducing insulin secretion in a glucose-dependent manner and compounds for use in these methods. The compounds may have the structure of formula I(a): wherein the substituents are as described in the description; or a pharmaceutically acceptable form thereof.
    Type: Grant
    Filed: March 19, 2018
    Date of Patent: January 17, 2023
    Assignees: The Broad Institute, Inc., The General Hospital Corporation, Instituto Carlos Slim de la Salud, A.C.
    Inventors: Sean M. Burns, Bridget K. Wagner, Amedeo Vetere
  • COMPOUNDS AND METHODS FOR REGULATING INSULIN SECRETION
    Publication number: 20200017485
    Abstract: Disclosed herein are methods for inducing insulin secretion in a glucose-dependent manner and compounds for use in these methods.
    Type: Application
    Filed: March 19, 2018
    Publication date: January 16, 2020
    Applicants: The Broad Institute, Inc., The General Hospital Corporation
    Inventors: Sean M. BURNS, Bridget K. WAGNER, Amedeo VETERE
  • Propeptide-luciferase fusion proteins and methods of use thereof
    Patent number: 10370697
    Abstract: The present invention provides nucleic acid constructs that encode fusion peptides comprising a bioluminescent protein and a precursor of a secreted peptide or protein expressed at the cell surface and high throughput screening assays using same.
    Type: Grant
    Filed: May 19, 2017
    Date of Patent: August 6, 2019
    Assignees: THE BROAD INSTITUE, INC., THE GENERAL HOSPITAL CORPORATION, INSTITUTO CARLOS SLIM DE LA SALUD, A.C.
    Inventors: Sean Burns, David Altshuler, Amedeo Vetere
  • PROPEPTIDE-LUCIFERASE FUSION PROTEINS AND METHODS OF USE THEREOF
    Publication number: 20170260565
    Abstract: The present invention provides nucleic acid constructs that encode fusion peptides comprising a bioluminescent protein and a precursor of a secreted peptide or protein expressed at the cell surface and high throughput screening assays using same.
    Type: Application
    Filed: May 19, 2017
    Publication date: September 14, 2017
    Inventors: SEAN BURNS, DAVID ALTSHULER, AMEDEO VETERE
  • Propeptide-luciferase fusion proteins and methods of use thereof
    Patent number: 9657329
    Abstract: The present invention provides nucleic acid constructs that encode fusion peptides comprising a bioluminescent protein and a precursor of a secreted peptide or protein expressed at the cell surface and high throughput screening assays using same.
    Type: Grant
    Filed: November 7, 2012
    Date of Patent: May 23, 2017
    Assignees: The Broad Institute Inc., The General Hospital Corporation, Instituto Carlos slim de la Salud, A.C.
    Inventors: Sean Burns, David Altshuler, Amedeo Vetere
  • PROPEPTIDE-LUCIFERASE FUSION PROTEINS AND METHODS OF USE THEREOF
    Publication number: 20140303035
    Abstract: The present invention provides nucleic acid constructs that encode fusion peptides comprising a bioluminescent protein and a precursor of a secreted peptide or protein expressed at the cell surface and high throughput screening assays using same.
    Type: Application
    Filed: November 7, 2012
    Publication date: October 9, 2014
    Inventors: Sean Burns, David Altshuler, Amedeo Vetere