Patents by Inventor Amein Kadhem AL-ALI

Amein Kadhem AL-ALI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Primer compositions for detecting thalassemia
    Patent number: 11884981
    Abstract: One aspect of the invention is a method for amplifying alpha globin genes HBA1, HBA2 and HBA12 in a single PCR tube to determine an HBA genotype of a subject. This method employs five primers selected to accurate and sensitively identify the HBA1, HBA2, and HBA12, a gene found at a higher frequency in citizens of Saudi Arabia, by accurately annealing to nucleic acids in a biological sample and simultaneously amplifying sequences encoding the alpha globin genes. This invention includes a procedure and required reagents for the amplification of alpha globin genes in a single PCR tube.
    Type: Grant
    Filed: May 27, 2021
    Date of Patent: January 30, 2024
    Assignee: Imam Abdulrahman Bin Faisal University
    Inventors: J. Francis Borgio, Sayed Abdulazeez, Fahd A. Al-Muhanna, Amein Kadhem Al-Ali
  • PRIMER COMPOSITIONS FOR DETECTING THALASSEMIA
    Publication number: 20210285051
    Abstract: One aspect of the invention is a method for amplifying alpha globin genes HBA1, HBA2 and HBA12 in a single PCR tube to determine an HBA genotype of a subject. This method employs five primers selected to accurate and sensitively identify the HBA1, HBA2, and HBA12, a gene found at a higher frequency in citizens of Saudi Arabia, by accurately annealing to nucleic acids in a biological sample and simultaneously amplifying sequences encoding the alpha globin genes. This invention includes a procedure and required reagents for the amplification of alpha globin genes in a single PCR tube.
    Type: Application
    Filed: May 27, 2021
    Publication date: September 16, 2021
    Applicant: King Faisal Street, Eastern Province
    Inventors: J. Francis BORGIO, Sayed ABDULAZEEZ, Fahd A. AL-MU HANNA, Amein Kadhem AL-ALI
  • Single tube multiplex PCR method for the detection of HBA1, HBA2 and HBA12 genes
    Patent number: 11118229
    Abstract: One aspect of the invention is a method for amplifying alpha globin genes HBA1, HBA2 and HBA12 in a single PCR tube to determine an HBA genotype of a subject. This method employs five primers selected to accurate and sensitively identify the HBA1, HBA2, and HBA12, a gene found at a higher frequency in citizens of Saudi Arabia, by accurately annealing to nucleic acids in a biological sample and simultaneously amplifying sequences encoding the alpha globin genes. This invention includes a procedure and required reagents for the amplification of alpha globin genes in a single PCR tube.
    Type: Grant
    Filed: January 25, 2019
    Date of Patent: September 14, 2021
    Assignee: Imam Abdulrahman Bin Faisal University
    Inventors: J. Francis Borgio, Sayed Abdulazeez, Fahd A. Al-Muhanna, Amein Kadhem Al-Ali
  • SINGLE TUBE MULTIPLEX PCR METHOD FOR THE DETECTION OF HBA1, HBA2 AND HBA12 GENES
    Publication number: 20200239956
    Abstract: One aspect of the invention is a method for amplifying alpha globin genes HBA1, HBA2 and HBA12 in a single PCR tube to determine an HBA genotype of a subject. This method employs five primers selected to accurate and sensitively identify the HBA1, HBA2, and HBA12, a gene found at a higher frequency in citizens of Saudi Arabia, by accurately annealing to nucleic acids in a biological sample and simultaneously amplifying sequences encoding the alpha globin genes. This invention includes a procedure and required reagents for the amplification of alpha globin genes in a single PCR tube.
    Type: Application
    Filed: January 25, 2019
    Publication date: July 30, 2020
    Applicant: Imam Abdulrahman Bin Faisal University
    Inventors: J. Francis BORGIO, Sayed ABDULAZEEZ, Fahd A. AL-MUHANNA, Amein Kadhem AL-ALI
  • Sequence specific primer pool for multiplex PCR and method of detecting microbial infections in thalassemia patients
    Patent number: 9863009
    Abstract: Reagents and methods for the fast, accurate and early detection of infections in thalassemia major patients. Reagents include a primer pool containing a mixture of primer pairs for the specific recognition and simultaneous amplification of targeted gene sequences of pathogens from a biological sample collected from a patient in a multiplex PCR reaction. Pathogens may include at least one Fungi species, Klebsiella pneumoniae, Candida albicans and Staphylococcus aureus. Subsequent identification of the pathogens is achieved by DNA sequencing analysis.
    Type: Grant
    Filed: October 20, 2014
    Date of Patent: January 9, 2018
    Assignee: University of Dammam
    Inventors: Amein Kadhem Al-Ali, Francis Borgio Jesu Alexander, Zaki Naserullah, Sayed Abdul Azeez, Sana Al-Jarrash
  • SEQUENCE SPECIFIC PRIMER POOL FOR MULTIPLEX PCR AND METHOD OF DETECTING MICROBIAL INFECTIONS IN THALASSEMIA PATIENTS
    Publication number: 20160083806
    Abstract: Reagents and methods for the fast, accurate and early detection of infections in thalassemia major patients. Reagents include a primer pool containing a mixture of primer pairs for the specific recognition and simultaneous amplification of targeted gene sequences of pathogens from a biological sample collected from a patient in a multiplex PCR reaction. Pathogens may include at least one Fungi species, Klebsiella pneumoniae, Candida albicans and Staphylococcus aureus. Subsequent identification of the pathogens is achieved by DNA sequencing analysis.
    Type: Application
    Filed: October 20, 2014
    Publication date: March 24, 2016
    Applicant: University of Dammam
    Inventors: Amein Kadhem AL-ALI, Francis Borgio Jesu Alexander, Zaki Naserullah, Sayed Abdul Azeez, Sana Al-Jarrash