Abstract: Microcapsules are described that include a pharmaceutical active agent selected from among retinoids, an anionic hydrophilic polymer (in particular, gum arabic), and a cationic hydrophilic polymer (in particular, type-A gelatin). Also described, are methods for preparing such microcapsules, topical pharmaceutical compositions including such microcapsules, and dermatological uses thereof.

Abstract: Compositions including at least 3?-tert-butyl-4?-(2-hydroxy-ethoxy)-4?-pyrrolidin-1-yl-[1,1?;3,1?]-terphenyl-4-carboxylic acid are described. The compositions can be oil-in-water emulsions made up of oily liquid globules each provided with a lamellar liquid crystal coating dispersed in an aqueous phase; a retinoid is either in the oily liquid globules or in the aqueous phase; each oily liquid globule is individually coated with a unilamellar or oligolamellar layer, obtained from at least one lipophilic surfactant, at least one hydrophilic surfactant and at least one separate anionic surfactant, and the coated oily liquid globules have a mean diameter lower than 800 nm.