Abstract: The present invention concerns the antidiabetic activity of compounds type A, namely of 8-?-D-glucosylgenistein, which is not toxic to eukaryotic cells and has demonstrated to produce complete normalization of fasting hyperglycaemia, to reduce excessive postprandial glucose excursion, to increase glucose-induced insulin secretion and insulin sensitivity. An alternative synthesis for this molecular entity and its binding ability to ?-amyloid oligomers is also included in the present invention, which also comprises Genista tenera ethyl acetate extract for use as antihyperglycaemic agent i.e. for lowering blood glucose levels in mammals that are pre-diabetic or have type 2 or type 1 diabetes. The inhibitory activity of ?-glucosidase by Genista tenera ethyl acetate and butanol extracts and that of glucose-6-phosphastase by these two extracts and the diethyl ether plant extract is also part of the present invention.

Abstract: The present invention concerns the antidiabetic-activity of compounds type A, namely of 8-?-D-glucosylgenistein, which is not toxic to eukaryotic cells and has demonstrated to produce complete normalization of fasting hyperglycaemia, to reduce excessive postprandial glucose excursion, to increase glucose-induced insulin secretion and insulin sensitivity. An alternative synthesis for this molecular entity and its binding ability to ?-amyloid oligomers is also included in the present invention, which also comprises Genista tenera ethyl acetate extract for use as antihyperglycaemic, agent i.e. for lowering blood glucose levels in mammals that are pre-diabetic or have type 2 or type 1 diabetes. The inhibitory activity of ?-glucosidase by Genista tenera ethyl acetate and butanol extracts and that of glucose-6-phosphatase by these two extracts and the diethyl ether plant extract is also part of the present invention.

Abstract: Pesticidal compounds of general formula (I) Wherein ?represents a double bond; A— represents ?C(R5)—C(?O)—, wherein R represents hydrogen or halogen, R1 and R2 represent, independently, hydrogen, halogen, alkoxy, substituted alkoxy or an ester group; or R1 and R2, together with the carbon atoms to which they are attached, represent an oxirane ring; or R1 and R2, taken together, represent an alkylidenedioxy or substituted alkylidenedioxy group; and R3 represents —CH2R6, wherein R6 represents an ester group, oxiranyl, or a group of formula wherein R7 represents hydrogen or alkyl, R8 represents phenylsulfanyl, phenylselenyl, phenylsulfoxy or phenylselenoxy, and R9 represents hydrogen, ethoxycarbonyl or carbamoyl and R4 represents, independently, hydrogen, alkoxy or substituted alkoxy; and methods of making the compounds of formula (I) and methods for controlling pests wherein the pest dies as a result of contact with a compound of formula (I).

Abstract: A method for controlling pests, the method comprising applying an effective amount to pests or their locus of one or more compounds of general formula (I) wherein R1 and R2 represent, independently from each other, hydrogen, halogen, alkoxy, substituted alkoxy or an ester group; R1 and R2, together with the carbon atoms to which they are attached, represent an oxirane ring; R1 and R2, taken together, represent an akylidenedioxy or substituted alkylidenedioxy group; and R3 represents —CH2R6, wherein R6 represents an ester group, oxiranyl, or a group of formula wherein R7 represents hydrogen or alkyl, R8 represents phenylsulfanyl, phenylselenyl, phenylsulfoxy or phenylselenoxy, and R9 represents hydrogen, ethoxycarbonyl or carbamoyl; and R4 represents, independently, hydrogen, alkoxy or substituted alkoxy, or R1 and R4, taken together, represent an alkylidenedioxy or a substituted alkylidenedioxy group; wherein the pest dies as a result of contact with the compound.

Abstract: The present invention relates to pesticidal compounds with general formula (I), their preparation and application to said pests or their locus, wherein represents C—C single or double bond; represents —CH(R4)—, if said C—C is a single bond, R4 hydrogen, alkoxy or substituted alkoxy, or R1, R4, taken together, form an alkylidenedioxy or substituted alkylidenedioxy group; or represents ?C(R5)—C(?O)—, if said C—C is a double bond, R5 hydrogen, halogen; R1, R2-hydrogen, halogen, alkoxy, substituted alkoxy or ester group, or R1, R2, taken together with the carbon atoms to which they are attached, represent an oxirane ring; or R1, R2, taken together, represent an alkylidenedioxy or substituted alkylidenedioxy group; R3 represents —CH2R6 (R6-ester group), oxiranyl, or a group of formula wherein R7 is hydrogen or alkyl, R8 phenylsulfanyl, phenylselenyl, phenylsulfoxy or phenylselenoxy; and R9 hydrogen, ethoxycarbonyl or carbamoyl.