Abstract: Provided is an elevator apparatus that may be mounted horizontally in an upper portion of an elevator hoistway. Such an elevator apparatus may comprise a drive machine, a deflector sheave, a support frame, and a roping system. The roping system may be configured to eliminate reverse rope bend to improve the rope life of the system.

Abstract: The invention provides an adenovirus that expresses a constitutively activated form of human NF-?B activating kinase (IKK). Co-administration of the adenovirus expressing the constitutively activated form of IKK (Ad-IKK?) and an antigen confers an enhanced immune response against the antigen relative to co-administration of the antigen and adenovirus that do not express IKK. Optionally, the adenovirus comprises one or more heterologous nucleic acid sequences that may encode, for example, a biologically active product such as the antigen of an infectious agent (e.g., bacterial, fungal, etc.) or a tumor antigen. Accordingly, the adenovirus is useful for inducing desired immune responses such as those against infectious agents and cancer cells.