Patents by Inventor Ameya Umesh Borwankar

Ameya Umesh Borwankar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD OF CONTROLLING THE PINK COLOR GENERATED DURING ANTIBODY MANUFACTURING
    Publication number: 20230103511
    Abstract: The invention is a method of preventing the generation of pink color during antibody manufacturing by either preventing the reduction of antibodies during manufacturing and harvest or inhibiting the conversion of cyanocobalamin (CN-Cbl) to hydroxocobalamin (HO-Cbl) during manufacturing and harvest. Replacement of white light in the cell culture media preparation and storage areas with red light inhibits the conversion of CN-Cbl to HO-Cbl. Addition of peroxides to the clarified bulk at harvest inhibits reduction of the antibody disulfide bonds.
    Type: Application
    Filed: May 8, 2018
    Publication date: April 6, 2023
    Applicant: BRISTOL-MYERS SQUIBB COMPANY
    Inventors: Cheng DU, Ameya Umesh BORWANKAR, Joon Chong YEE, Zhijun TAN
  • IMPROVED PROTEIN RECOVERY
    Publication number: 20210171573
    Abstract: This disclosure provides a novel flush method using a recovery flush technique that minimizes yield losses due to inadequate flushing and prevents or reduces dilution of a target protein during a recovery flush.
    Type: Application
    Filed: August 13, 2019
    Publication date: June 10, 2021
    Inventors: Abhiram Arunkumar, Nripen Singh, Ameya Umesh Borwankar