Patents by Inventor Ami A. Shah

Ami A. Shah has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220412980
    Abstract: This document relates to materials and methods for assessing and/or treating subjects (e.g., subjects having autoimmune diseases). For example, materials and methods for determining if a subject (e.g., a human having an autoimmune disease) has one or more antibodies that can be used to identify the subject as having a lower risk of cancer or as having a higher risk of cancer are provided. Materials and methods for treating a subject (e.g., a human) identified as having a higher cancer risk for cancer are also provided.
    Type: Application
    Filed: August 18, 2022
    Publication date: December 29, 2022
    Inventors: Ami A. Shah, Livia Casciola-Rosen, Antony Rosen, Takeru Igusa, Marikki K. Laiho
  • Patent number: 11454630
    Abstract: This document relates to materials and methods for assessing and/or treating subjects (e.g., subjects having autoimmune diseases). For example, materials and methods for determining if a subject (e.g., a human having an autoimmune disease) has one or more antibodies that can be used to identify the subject as having a lower risk of cancer or as having a higher risk of cancer are provided. Materials and methods for treating a subject (e.g., a human) identified as having a higher cancer risk for cancer are also provided.
    Type: Grant
    Filed: August 23, 2018
    Date of Patent: September 27, 2022
    Assignee: The Johns Hopkins University
    Inventors: Ami A. Shah, Livia Casciola-Rosen, Antony Rosen, Takeru Igusa, Marikki K. Laiho
  • Publication number: 20210100882
    Abstract: Autoimmune diseases are thought to be initiated by exposures to foreign antigens that cross-react with endogenous molecules. Analyses of peripheral blood lymphocytes and serum suggested that mutations in autoimmune antigen targets sparked cellular immunity and cross-reactive humoral immune responses. Acquired immunity to autoimmune antigens can help control naturally occurring cancers.
    Type: Application
    Filed: October 22, 2020
    Publication date: April 8, 2021
    Inventors: Erika Darrah, Ami A. Shah, Livia A. Casciola-Rosen, Antony Rosen, Christine Joseph, Bert Vogelstein, Kenneth W. Kinzler, Nickolas Papadopoulos
  • Patent number: 10874726
    Abstract: Autoimmune diseases are thought to be initiated by exposures to foreign antigens that cross-react with endogenous molecules. Analyses of peripheral blood lymphocytes and serum suggested that mutations in autoimmune antigen targets sparked cellular immunity and cross-reactive humoral immune responses. Acquired immunity to autoimmune antigens can help control naturally occurring cancers.
    Type: Grant
    Filed: December 4, 2014
    Date of Patent: December 29, 2020
    Assignee: The Johns Hopkins University
    Inventors: Erika Darrah, Ami A. Shah, Livia A. Casciola-Rosen, Antony Rosen, Christine Joseph, Bert Vogelstein, Kenneth W. Kinzler, Nickolas Papadopoulos
  • Publication number: 20200209245
    Abstract: This document relates to materials and methods for assessing and/or treating subjects (e.g., subjects having autoimmune diseases). For example, materials and methods for determining if a subject (e.g., a human having an autoimmune disease) has one or more antibodies that can be used to identify the subject as having a lower risk of cancer or as having a higher risk of cancer are provided. Materials and methods for treating a subject (e.g., a human) identified as having a higher cancer risk for cancer are also provided.
    Type: Application
    Filed: August 23, 2018
    Publication date: July 2, 2020
    Inventors: Ami A. Shah, Livia Casciola-Rosen, Antony Rosen, Takeru Igusa, Marikki K. Laiho
  • Patent number: 10066183
    Abstract: In one aspect, lubricant compositions are described herein. In some embodiments, a lubricant composition described herein comprises a grease and milled metal sulfide particles dispersed in the grease. In other cases, a lubricant composition described herein comprises a grease, polytetrafluroethylene particles, zinc dithiophosphate, and molybdenum dialkyldithiocarbamate, wherein the polytetrafluroethylene particles, zinc dithiophosphate, and molybdenum dialkyldithiocarbamate are dispersed in the grease.
    Type: Grant
    Filed: September 8, 2016
    Date of Patent: September 4, 2018
    Assignee: Board of Regents, The University of Texas System
    Inventors: Pranesh B. Aswath, Sujay Bagi, Ami Shah, Kush Shah, Kane Mordaunt
  • Publication number: 20170066990
    Abstract: In one aspect, lubricant compositions are described herein. In some embodiments, a lubricant composition described herein comprises a grease and milled metal sulfide particles dispersed in the grease. In other cases, a lubricant composition described herein comprises a grease, polytetrafluroethylene particles, zinc dithiophosphate, and molybdenum dialkylthiocarbamate, wherein the polytetrafluroethylene particles, zinc dithiophosphate, and molybdenum dialkyldithiocarbamate are dispersed in the grease.
    Type: Application
    Filed: September 8, 2016
    Publication date: March 9, 2017
    Inventors: Pranesh B. ASWATH, Sujay BAGI, Ami SHAH, Kush SHAH, Kane MORDAUNT
  • Publication number: 20160303209
    Abstract: Autoimmune diseases are thought to be initiated by exposures to foreign antigens that cross-react with endogenous molecules. Analyses of peripheral blood lymphocytes and serum suggested that mutations in autoimmune antigen targets sparked cellular immunity and cross-reactive humoral immune responses. Acquired immunity to autoimmune antigens can help control naturally occurring cancers.
    Type: Application
    Filed: December 4, 2014
    Publication date: October 20, 2016
    Applicant: The Johns Hopkins University
    Inventors: Erika Darrah, Ami A. Shah, Livia A. Casciola-Rosen, Anthony Rosen, Christine Joseph, Bert Vogelstein, Kenneth W. Kinzler, Nickolas Papadopoulos
  • Patent number: 8444994
    Abstract: A multivalent anthelmintic vaccine targets both hookworm and schistosomiasis. The vaccine includes, at a minimum, a recombinant third-stage larval hookworm antigen, a recombinant adult stage hookworm antigen, and a recombinant schistosome antigen. Preferably, the hookworm antigens are Necator americanus antigens, although antigens from other hookworm species (e.g. Ancylostoma duodenale) may also be employed. The schistosome antigen is preferably a Schistosoma mansoni or a Schistosoma haematobium antigen although antigens from other schistosome species (e.g. Schistosoma japonicum) may also be employed. In some cases full or partial sequences of schistosome antigens may be fused with full or partial sequences of hookworm {Necator americanus) to produce recombinant chimeric antigens.
    Type: Grant
    Filed: June 30, 2009
    Date of Patent: May 21, 2013
    Assignees: The Albert B. Sabin Vaccine Institute, The George Washington University, The Council of the Queensland Institute of Medical Research
    Inventors: Peter Hotez, Alexander Loukas, Mark Pearson, Jeffrey Bethony, Bin Zhan, Gaddam Goud, Maria Elena Bottazzi, David Diemert, Ami Shah Brown, Peter Giacomautonio
  • Publication number: 20110200640
    Abstract: A multivalent anthelmintic vaccine targets both hookworm and schistosomiasis. The vaccine includes, at a minimum, a recombinant third-stage larval hookworm antigen, a recombinant adult stage hookworm antigen, and a recombinant schistosome antigen. Preferably, the hookworm antigens are Necator americanus antigens, although antigens from other hookworm species (e.g. Ancylostoma duodenale) may also be employed. The schistosome antigen is preferably a Schistosoma mansoni or a Schistosoma haematobium antigen although antigens from other schistosome species (e.g. Schistosoma japonicum) may also be employed. In some cases full or partial sequences of schistosome antigens may be fused with full or partial sequences of hookworm {Necator americanus) to produce recombinant chimeric antigens.
    Type: Application
    Filed: June 30, 2009
    Publication date: August 18, 2011
    Inventors: Peter Hotez, Alexander Loukas, Mark Pearson, Jeffrey Bethony, Bin Zhan, Gaddam Goud, Maria Elena Bottazzi, David Diemert, Ami Shah Brown, Peter Giacomantonio