Patents by Inventor Amin I. Kassis

Amin I. Kassis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220298583
    Abstract: This invention provides methods of using cell free bodily fluid and blood cells in the diagnosis, prognosis, or monitoring of diseases or conditions. The invention also relates to methods of using cell free bodily fluid and blood cells to identify markers of diseases or conditions.
    Type: Application
    Filed: April 8, 2022
    Publication date: September 22, 2022
    Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventor: Amin I. KASSIS
  • Publication number: 20220298582
    Abstract: This invention provides methods of using cell free bodily fluid and blood cells in the diagnosis, prognosis, or monitoring of diseases or conditions. The invention also relates to methods of using cell free bodily fluid and blood cells to identify markers of diseases or conditions.
    Type: Application
    Filed: April 8, 2022
    Publication date: September 22, 2022
    Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventor: Amin I. KASSIS
  • Patent number: 11111537
    Abstract: This invention provides methods of using phagocytic cells alone or in combination with non-phagocytic cells in the diagnosis, prognosis, or monitoring of autoimmune or immune-related diseases or conditions. The invention also provides methods of using phagocytic cells alone or in combination with non-phagocytic cells to identify markers of autoimmune or immune-related diseases or conditions.
    Type: Grant
    Filed: February 3, 2016
    Date of Patent: September 7, 2021
    Assignee: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventor: Amin I. Kassis
  • Publication number: 20210238697
    Abstract: Methods and compositions for diagnosing the presence of a cancer cell in an individual are provided. Methods and compositions for identifying a tumor-specific signature in an individual having cancer are also provided. Methods and compositions for diagnosing the presence of an infectious agent in an individual and/or for identifying an infectious agent-specific signature in an infected individual are provided. Methods and compositions for diagnosing the presence of a disease in an individual are also provided. Methods and compositions for identifying a disease-specific signature in an individual having the disease are also provided.
    Type: Application
    Filed: April 19, 2021
    Publication date: August 5, 2021
    Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventor: Amin I. KASSIS
  • Patent number: 11001894
    Abstract: Methods and compositions for diagnosing the presence of a cancer cell in an individual are provided. Methods and compositions for identifying a tumor-specific signature in an individual having cancer are also provided. Methods and compositions for diagnosing the presence of an infectious agent in an individual and/or for identifying an infectious agent-specific signature in an infected individual are provided. Methods and compositions for diagnosing the presence of a disease in an individual are also provided. Methods and compositions for identifying a disease-specific signature in an individual having the disease are also provided.
    Type: Grant
    Filed: June 8, 2017
    Date of Patent: May 11, 2021
    Assignee: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventor: Amin I. Kassis
  • Patent number: 10961578
    Abstract: This invention provides methods of using phagocytic cells alone or in combination with non-phagocytic cells in the diagnosis, prognosis, or monitoring of prenatal or pregnancy-related diseases or conditions. The invention also provides methods of using phagocytic cells alone or in combination with non-phagocytic cells to identify markers of prenatal or pregnancy-related diseases or conditions.
    Type: Grant
    Filed: January 29, 2016
    Date of Patent: March 30, 2021
    Assignee: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventor: Amin I. Kassis
  • Patent number: 10934588
    Abstract: Methods and compositions for diagnosing the presence of a cancer cell in an individual are provided. Methods and compositions for identifying a tumor-specific signature in an individual having cancer are also provided. Methods and compositions for diagnosing the presence of an infectious agent in an individual and/or for identifying an infectious agent-specific signature in an infected individual are provided. Methods and compositions for diagnosing the presence of a disease in an individual are also provided. Methods and compositions for identifying a disease-specific signature in an individual having the disease are also provided.
    Type: Grant
    Filed: December 29, 2015
    Date of Patent: March 2, 2021
    Assignee: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventor: Amin I. Kassis
  • Patent number: 10934589
    Abstract: Methods and compositions for diagnosing the presence of a cancer cell in an individual are provided. Methods and compositions for identifying a tumor-specific signature in an individual having cancer are also provided. Methods and compositions for diagnosing the presence of an infectious agent in an individual and/or for identifying an infectious agent-specific signature in an infected individual are provided. Methods and compositions for diagnosing the presence of a disease in an individual are also provided. Methods and compositions for identifying a disease-specific signature in an individual having the disease are also provided.
    Type: Grant
    Filed: October 31, 2016
    Date of Patent: March 2, 2021
    Assignee: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventor: Amin I. Kassis
  • Publication number: 20200332366
    Abstract: This invention provides a set of biological markers that are useful for detecting cancer. This invention further provides methods of using those biological markers for the diagnosis, prognosis, or monitoring of cancer.
    Type: Application
    Filed: December 2, 2019
    Publication date: October 22, 2020
    Inventors: Amin I. Kassis, Harry Stylli, Colleen Kelly, Geoffrey Erickson, Kirk J. Wonjo
  • Publication number: 20200318201
    Abstract: The invention described herein provides biological markers for the diagnosis, prognosis, and monitoring of prostate cancer
    Type: Application
    Filed: April 20, 2020
    Publication date: October 8, 2020
    Inventors: Amin I. Kassis, Harry Stylli, Colleen Kelly, Geoffrey Erickson, Kirk J. Wojno
  • Publication number: 20200130891
    Abstract: A capsule for covering the top of a bottle includes a lower portion configured to wrap about a neck of the bottle, an upper portion connected to the lower portion and configured to be removed from the lower portion to expose a top of the neck, and a trench formed about a periphery of an upper edge of the lower portion. An assembly used to form the trench in the capsule includes a housing, and a blade extending outwardly from the housing.
    Type: Application
    Filed: November 18, 2019
    Publication date: April 30, 2020
    Inventors: Amin I. Kassis, Sousan Kanbar, Lana Kassis, Maya Kassis
  • Patent number: 10626464
    Abstract: The invention described herein provides biological markers for the diagnosis, prognosis, and monitoring of prostate cancer.
    Type: Grant
    Filed: September 11, 2015
    Date of Patent: April 21, 2020
    Assignee: Cell MDX, LLC
    Inventors: Amin I. Kassis, Harry Stylli, Colleen Kelly, Geoffrey Erickson, Kirk J. Wojno
  • Publication number: 20200040404
    Abstract: The present invention relates to compositions and methods for assessing prostate cancer (e.g., identification of the aggressiveness or indolence of prostate cancer) in a subject. The compositions and methods include obtaining subject specific information (e.g., age, digital rectal exam (DRE) data, prostate volume, total prostate-specific antigen (PSA)) and obtaining a biological sample from a subject and determining a measurement for a panel of biomarkers in the biological sample. Compositions and methods of the invention find use in both clinical and research settings, for example, within the fields of biology, immunology, medicine, and oncology.
    Type: Application
    Filed: July 31, 2019
    Publication date: February 6, 2020
    Inventors: Amin I. Kassis, Ricardo Henao, Kirk Wojno, Geoffrey Erickson, Harry Stylli
  • Patent number: 10494675
    Abstract: This invention provides a set of biological markers that are useful for detecting cancer. This invention further provides methods of using those biological markers for the diagnosis, prognosis, or monitoring of cancer.
    Type: Grant
    Filed: March 7, 2014
    Date of Patent: December 3, 2019
    Assignee: Cell MDX, LLC
    Inventors: Amin I. Kassis, Harry Stylli, Colleen Kelly, Geoffrey Erickson, Kirk J. Wojno
  • Publication number: 20190085402
    Abstract: This invention provides methods of using cell free bodily fluid and blood cells in the diagnosis, prognosis, or monitoring of diseases or conditions. The invention also relates to methods of using cell free bodily fluid and blood cells to identify markers of diseases or conditions.
    Type: Application
    Filed: April 17, 2018
    Publication date: March 21, 2019
    Applicant: President and Fellows of Harvard College
    Inventor: Amin I. KASSIS
  • Publication number: 20180327140
    Abstract: A capsule for covering the top of a bottle includes a lower portion configured to wrap about a neck of the bottle, an upper portion connected to the lower portion and configured to be removed from the lower portion to expose a top of the neck, and a trench formed about a periphery of an upper edge of the lower portion. An assembly used to form the trench in the capsule includes a housing, and a blade extending outwardly from the housing.
    Type: Application
    Filed: November 4, 2016
    Publication date: November 15, 2018
    Inventors: Amin I. Kassis, Sousan Kanbar, Lana Kassis, Maya Kassis
  • Publication number: 20180258488
    Abstract: This invention provides methods of using phagocytic cells in the diagnosis, prognosis, or monitoring of diseases or conditions. The invention also provides methods of using phagocytic cells to identify markers of diseases or conditions.
    Type: Application
    Filed: May 10, 2018
    Publication date: September 13, 2018
    Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventor: Amin I. KASSIS
  • Publication number: 20180119226
    Abstract: Methods and compositions for diagnosing the presence of a cancer cell in an individual are provided. Methods and compositions for identifying a tumor-specific signature in an individual having cancer are also provided. Methods and compositions for diagnosing the presence of an infectious agent in an individual and/or for identifying an infectious agent-specific signature in an infected individual are provided. Methods and compositions for diagnosing the presence of a disease in an individual are also provided. Methods and compositions for identifying a disease-specific signature in an individual having the disease are also provided.
    Type: Application
    Filed: June 8, 2017
    Publication date: May 3, 2018
    Inventor: Amin I. Kassis
  • Publication number: 20170268061
    Abstract: This invention provides methods of using phagocytic cells in the diagnosis, prognosis, or monitoring of diseases or conditions. The invention also provides methods of using phagocytic cells to identify markers of diseases or conditions.
    Type: Application
    Filed: June 8, 2017
    Publication date: September 21, 2017
    Inventor: Amin I. Kassis
  • Patent number: 9764079
    Abstract: Kits and methods provide for the isolation of white blood cells from bodily fluids. In one exemplary aspect, a method for isolating white blood cells from blood includes the act of adding a blood sample to a separation tube having a distal end, a proximal end, and a valve located proximate said proximal end, said valve being configured to transition between at least first, second, and third positions. The method also includes the act of removably attaching a cap to the distal end, centrifuging the separation tube with the valve in the first position, removing the cap at the distal end of the separation tube and removably attaching a first syringe to the proximal end, switching the valve to the second position and withdrawing, via the first syringe, a red blood cell sediment.
    Type: Grant
    Filed: April 12, 2013
    Date of Patent: September 19, 2017
    Assignee: President and Fellows of Harvard College
    Inventor: Amin I. Kassis