Patents by Inventor Amin ZHANG

Amin ZHANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIBODIES TO CD3 AND BCMA, AND BISPECIFIC BINDING PROTEINS MADE THEREFROM
    Publication number: 20230002489
    Abstract: High-affinity antibodies recognizing CD3 and B Cell Maturation Factor protein (BCMA) are disclosed. Binding sites from humanized anti-CD3 and anti-BCMA antibodies are incorporated into a Fabs-in-Tandem Immunoglobulin format without significant loss of binding affinity, and the resultant bispecific, multivalent binding proteins are able to bind to both CD3 and BCMA simultaneously. Such antibodies, antigen-binding portions thereof, and bispecific FIT-Ig binding proteins are useful for treating cancer.
    Type: Application
    Filed: November 26, 2020
    Publication date: January 5, 2023
    Inventors: Chengbin WU, Danqing WU, Lini HUANG, Amin ZHANG, Zhengrong SHUAI, Rui ZHANG, Shiyong GONG, Xuan WU