Patents by Inventor Amine Abbadi
Amine Abbadi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11952581Abstract: The present invention relates to a process for the production of polyunsaturated fatty acids in an organism by introducing, into the organism, nucleic acids which encode polypeptides with ?5-elongase activity. Advantageously, these nucleic acids can be expressed in the organism together with further nucleic acids which encode polypeptides of the biosynthesis of the fatty acid or lipid metabolism. Especially advantageous are nucleic acids which encode ?6-desaturases, ?5-desaturases, ?4-desaturases and/or ?6-elongases. These desaturases and elongases are advantageously derived from Thalassiosira, Euglena or Ostreococcus. The invention furthermore relates to a process for the production of oils and/or triacylglycerides with an elevated content of long-chain polyunsaturated fatty acids, and oils and/or triacylglycerides thus obtained.Type: GrantFiled: November 22, 2021Date of Patent: April 9, 2024Assignee: BASF PLANT SCIENCE GMBHInventors: Thorsten Zank, Jörg Bauer, Petra Cirpus, Amine Abbadi, Ernst Heinz, Xiao Qiu, Patricia Vrinten, Petra Sperling, Frederic Domergue, Astrid Schmidt, Helene Kirsch
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Publication number: 20220162629Abstract: The present invention relates to a process for the production of polyunsaturated fatty acids in an organism by introducing, into the organism, nucleic acids which encode polypeptides with ?5-elongase activity. Advantageously, these nucleic acids can be expressed in the organism together with further nucleic acids which encode polypeptides of the biosynthesis of the fatty acid or lipid metabolism. Especially advantageous are nucleic acids which encode ?6-desaturases, ?5-desaturases, ?4-desaturases and/or ?6-elongases. These desaturases and elongases are advantageously derived from Thalassiosira, Euglena or Ostreococcus. The invention furthermore relates to a process for the production of oils and/or triacylglycerides with an elevated content of long-chain polyunsaturated fatty acids, and oils and/or triacylglycerides thus obtained.Type: ApplicationFiled: November 22, 2021Publication date: May 26, 2022Inventors: Thorsten Zank, Jörg Bauer, Petra Cirpus, Amine Abbadi, Ernst Heinz, Xiao Qiu, Patricia Vrinten, Petra Sperling, Frederic Domergue, Astrid Schmidt, Helene Kirsch
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Patent number: 11180769Abstract: The present invention relates to a process for the production of polyunsaturated fatty acids in an organism by introducing, into the organism, nucleic acids which encode polypeptides with ?5-elongase activity. Advantageously, these nucleic acids can be expressed in the organism together with further nucleic acids which encode polypeptides of the biosynthesis of the fatty acid or lipid metabolism. Especially advantageous are nucleic acids which encode ?6-desaturases, ?5-desaturases, ?4-desaturases and/or ?6-elongases. These desaturases and elongases are advantageously derived from Thalassiosira, Euglena or Ostreococcus. The invention furthermore relates to a process for the production of oils and/or triacylglycerides with an elevated content of long-chain polyunsaturated fatty acids, and oils and/or triacylglycerides thus obtained.Type: GrantFiled: July 11, 2019Date of Patent: November 23, 2021Assignee: BASF PLANT SCIENCE GMBHInventors: Thorsten Zank, Jörg Bauer, Petra Cirpus, Amine Abbadi, Ernst Heinz, Xiao Qiu, Patricia Vrinten, Petra Sperling, Frederic Domergue, Astrid Schmidt, Helene Kirsch
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Publication number: 20190323024Abstract: The present invention relates to a process for the production of polyunsaturated fatty acids in an organism by introducing, into the organism, nucleic acids which encode polypeptides with ?5-elongase activity. Advantageously, these nucleic acids can be expressed in the organism together with further nucleic acids which encode polypeptides of the biosynthesis of the fatty acid or lipid metabolism. Especially advantageous are nucleic acids which encode ?6-desaturases, ?5-desaturases, ?4-desaturases and/or ?6-elongases. These desaturases and elongases are advantageously derived from Thalassiosira, Euglena or Ostreococcus. The invention furthermore relates to a process for the production of oils and/or triacylglycerides with an elevated content of long-chain polyunsaturated fatty acids, and oils and/or triacylglycerides thus obtained.Type: ApplicationFiled: July 11, 2019Publication date: October 24, 2019Inventors: Thorsten ZANK, Jörg BAUER, Petra CIRPUS, Amine ABBADI, Ernst HEINZ, Xiao QIU, Patricia VRINTEN, Petra SPERLING, Frederic DOMERGUE, Astrid SCHMIDT, Helene KIRSCH
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Publication number: 20170016015Abstract: The present invention relates to a process for the production of polyunsaturated fatty acids in an organism by introducing, into the organism, nucleic acids which encode polypeptides with ?5-elongase activity. Advantageously, these nucleic acids can be expressed in the organism together with further nucleic acids which encode polypeptides of the biosynthesis of the fatty acid or lipid metabolism. Especially advantageous are nucleic acids which encode ?6-desaturases, ?5-desaturases, ?4-desaturases and/or ?6-elongases. These desaturases and elongases are advantageously derived from Thalassiosira, Euglena or Ostreococcus. The invention furthermore relates to a process for the production of oils and/or triacylglycerides with an elevated content of long-chain polyunsaturated fatty acids, and oils and/or triacylglycerides thus obtained.Type: ApplicationFiled: August 16, 2016Publication date: January 19, 2017Inventors: Thorsten Zank, Jörg Bauer, Petra Cirpus, Amine Abbadi, Ernst Heinz, Xiao Qiu, Patricia Vrinten, Petra Sperling, Frederic Domergue, Astrid Meyer, Jelena Kirsch
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Patent number: 9433228Abstract: The invention relates to a method for the production of multiply-unsaturated fatty acids in an organism, into which nucleic acids have been introduced, which code for polypeptides with ?-5 elongase activity. Said nucleic acid sequences, optionally with further nucleic acid sequences, coding for polypeptides for the biosynthesis of fatty acids and lipid metabolism, are advantageously expressed in the organism. Nucleic acid sequences coding for a ?-6 desaturase, a ?-5 desaturase, ?-4 desaturase and/or ?-6 elongase activity are particularly advantageous and, advantageously, said saturases and elongases are derived from Thalassiosira, Euglena or Ostreococcus. The invention further relates to a method for the production of oils and/or triacylglycerides with an increased content of long-chain, multiply-unsaturated fatty acids.Type: GrantFiled: July 16, 2004Date of Patent: September 6, 2016Assignee: BASF Plant Science GmbHInventors: Thorsten Zank, Jörg Bauer, Petra Cirpus, Amine Abbadi, Ernst Heinz, Xiao Qiu, Patricia Vrinten, Petra Sperling, Frederic Domergue, Astrid Meyer, Jelena Kirsch
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Publication number: 20140026259Abstract: The present invention relates to a process for producing polyunsaturated fatty acids in an organism by introducing nucleic acids into the organism which code for polypeptides having acyl-CoA:lysophospholipid a cyltransferase activity. Advantageously, these nucleic acid sequences may, if appropriate together with further nucleic acid sequences coding for biosynthesis polypeptides of the fatty acid or lipid metabolism, be expressed in the transgenic organism. The invention furthermore relates to the nucleic acid sequences, to nucleic acid constructs comprising the nucleic acid sequences of the invention, to vectors comprising the nucleic acid sequences and/or the nucleic acid constructs and to transgenic organisms comprising the abovementioned nucleic acid sequences, nucleic acid constructs and/or vectors. A further part of the invention relates to oils, lipids and/or fatty acids produced by the process of the invention and to their use.Type: ApplicationFiled: June 7, 2013Publication date: January 23, 2014Inventors: Andreas Renz, Ernst Heinz, Amine Abbadi, Frederic Domergue, Thorsten Zank
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Patent number: 8486671Abstract: The present invention relates to a process for producing polyunsaturated fatty acids in an organism by introducing nucleic acids into the organism which code for polypeptides having acyl-CoA:lysophospholipid a cyltransferase activity. Advantageously, these nucleic acid sequences may, if appropriate together with further nucleic acid sequences coding for biosynthesis polypeptides of the fatty acid or lipid metabolism, be expressed in the transgenic organism. The invention furthermore relates to the nucleic acid sequences, to nucleic acid constructs comprising the nucleic acid sequences of the invention, to vectors comprising the nucleic acid sequences and/or the nucleic acid constructs and to transgenic organisms comprising the abovementioned nucleic acid sequences, nucleic acid constructs and/or vectors. A further part of the invention relates to oils, lipids and/or fatty acids produced by the process of the invention and to their use.Type: GrantFiled: April 2, 2009Date of Patent: July 16, 2013Assignee: BASF Plant Science GmbHInventors: Andreas Renz, Ernst Heinz, Amine Abbadi, Frederic Domergue, Thorsten Zank
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Patent number: 8354569Abstract: The invention relates to a process for the production of long-chain polyunsaturated fatty acids in an organism by introducing, into the organism, nucleic acids coding for polypeptides with acyltransferase activity. These nucleic acid sequences, if appropriate together with further nucleic acid sequences coding for polypeptides of the fatty acid or lipid metabolism biosynthesis, can advantageously be expressed in the organism. Furthermore, the invention relates to a method for the production of oils and/or triacylglycerides with an elevated content of long-chain polyunsaturated fatty acids. The invention furthermore relates to the nucleic acid sequences, and constructs, vectors and organisms comprising the nucleic acid sequences. A further part of the invention relates to oils, lipids and/or fatty acids produced by the process according to the invention and to their use.Type: GrantFiled: July 28, 2010Date of Patent: January 15, 2013Assignee: University of BristolInventors: Andreas Renz, Jörg Bauer, Margit Frentzen, Nursen Sözer, Stobart Keith, Thomas Fraser, Colin M. Lazarus, Baoxiu Qi, Amine Abbadi, Ernst Heinz
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Publication number: 20110023185Abstract: The invention relates to a process for the production of long-chain polyunsaturated fatty acids in an organism by introducing, into the organism, nucleic acids coding for polypeptides with acyltransferase activity. These nucleic acid sequences, if appropriate together with further nucleic acid sequences coding for polypeptides of the fatty acid or lipid metabolism biosynthesis, can advantageously be expressed in the organism. Furthermore, the invention relates to a method for the production of oils and/or triacylglycerides with an elevated content of long-chain polyunsaturated fatty acids. The invention furthermore relates to the nucleic acid sequences, and constructs, vectors and organisms comprising the nucleic acid sequences. A further part of the invention relates to oils, lipids and/or fatty acids produced by the process according to the invention and to their use.Type: ApplicationFiled: July 28, 2010Publication date: January 27, 2011Applicant: UNIVERSITY OF BRISTOLInventors: ANDREAS RENZ, JÖRG BAUER, MARGIT FRENTZEN, NURSEN SÖZER, STOBART KEITH, THOMAS FRASER, COLIN M. LAZARUS, BAOXIU QI, AMINE ABBADI, ERNST HEINZ
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Patent number: 7871804Abstract: The invention relates to a method for producing polyunsaturated fatty acids in an organism, according to which nucleic acids coding for polypeptides with an acyl-CoA:lysophospholipid-acyltransferase activity are introduced into the organism. Advantageously, the nucleic acid sequences can be expressed in the transgenic organism optionally together with other nucleic acid sequences coding for polypeptides of the fatty acid or lipid metabolism. The invention also relates to the inventive nucleic acid sequences, nucleic acid constructs containing the inventive nucleic acid sequences, vectors containing the inventive nucleic acid sequences and/or the nucleic acid constructs, and transgenic organisms containing the nucleic acid sequences, nucleic acid constructs and/or vectors. The invention further relates to oils, lipids and/or fatty acids produced according to the inventive method, and to the use of the same.Type: GrantFiled: December 20, 2005Date of Patent: January 18, 2011Assignee: BASF Plant Science GmbHInventors: Petra Cirpus, Jörg Bauer, Ernst Heinz, Amine Abbadi, Jelena Kirsch
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Patent number: 7855321Abstract: The present invention relates to a process for the production of long-chain polyunsaturated fatty acids in an organism by introducing, into the organism, nucleic acids which code for polypeptides with acyl transferase activity. These nucleic acid sequences, if appropriate together with further nucleic acid sequences which code for polypeptides of the fatty acid or lipid metabolism biosynthesis, can advantageously be expressed in the organism. Furthermore, the invention relates to a method for the production of oils and/or triacylglycerides with an elevated content of long-chain polyunsaturated fatty acids. The invention furthermore relates to the nucleic acid sequences, nucleic acid constructs, vectors and organisms comprising the nucleic acid sequences according to the invention, vectors comprising the nucleic acid sequences and/or the nucleic acid constructs and to transgenic organisms comprising the abovementioned nucleic acid sequences, nucleic acid constructs and/or vectors.Type: GrantFiled: March 26, 2004Date of Patent: December 21, 2010Assignee: University of BristolInventors: Andreas Renz, Jörg Bauer, Margit Frentzen, Nursen Sözer, Stobart Keith, Thomas Fraser, Colin M. Lazarus, Baoxiu Qi, Amine Abbadi, Ernst Heinz
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Publication number: 20090209774Abstract: The present invention relates to a process for producing polyunsaturated fatty acids in an organism by introducing nucleic acids into the organism which code for polypeptides having acyl-CoA:lysophospholipid a cyltransferase activity. Advantageously, these nucleic acid sequences may, if appropriate together with further nucleic acid sequences coding for biosynthesis polypeptides of the fatty acid or lipid metabolism, be expressed in the transgenic organism. The invention furthermore relates to the nucleic acid sequences, to nucleic acid constructs comprising the nucleic acid sequences of the invention, to vectors comprising the nucleic acid sequences and/or the nucleic acid constructs and to transgenic organisms comprising the abovementioned nucleic acid sequences, nucleic acid constructs and/or vectors. A further part of the invention relates to oils, lipids and/or fatty acids produced by the process of the invention and to their use.Type: ApplicationFiled: April 2, 2009Publication date: August 20, 2009Applicant: BASF Plant Science GmbHInventors: Andreas Renz, Ernst Heinz, Amine Abbadi, Frederic Domergue, Thorsten Zank
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Patent number: 7537920Abstract: The present invention relates to a process for producing polyunsaturated fatty acids in an organism by introducing nucleic acids into the organism which code for polypeptides having acyl-CoA:lysophospholipid a cyltransferase activity. Advantageously, these nucleic acid sequences may, if appropriate together with further nucleic acid sequences coding for biosynthesis polypeptides of the fatty acid or lipid metabolism, be expressed in the transgenic organism. The invention furthermore relates to the nucleic acid sequences, to nucleic acid constructs comprising the nucleic acid sequences of the invention, to vectors comprising the nucleic acid sequences and/or the nucleic acid constructs and to transgenic organisms comprising the abovementioned nucleic acid sequences, nucleic acid constructs and/or vectors. A further part of the invention relates to oils, lipids and/or fatty acids produced by the process of the invention and to their use.Type: GrantFiled: January 29, 2004Date of Patent: May 26, 2009Assignee: BASF Plant Science GmbHInventors: Andreas Renz, Ernst Heinz, Amine Abbadi, Frederic Domergue, Thorsten Zank
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Publication number: 20090094707Abstract: The invention relates to a method for producing polyunsaturated fatty acids in an organism, according to which nucleic acids coding for polypeptides with an acyl-CoA:lysophospholipid-acyltransferase activity am introduced into the organism. Advantageously, said nucleic acid sequences can be expressed in the transgenic organism optionally together with other nucleic acid sequences coding for polypeptides of the fatty acid or lipid metabolism. The invention also relates to the inventive nucleic acid sequences, nucleic acid constructs containing the inventive nucleic acid sequences, vectors containing the inventive nucleic acid sequences and/or the nucleic acid constructs, and transgenic organisms containing said nucleic acid sequences, nucleic acid constructs and/or vectors. The invention further relates to oils, lipids and/or fatty acids produced according to the inventive method, and to the use of the same.Type: ApplicationFiled: December 20, 2005Publication date: April 9, 2009Applicant: BASF PLANT SCIENCE GMBHInventors: Petra Cirpus, Jorg Bauer, Ernst Heinz, Amine Abbadi, Jelena Kirsch
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Publication number: 20080155705Abstract: The invention relates to a method for the production of multiply-unsaturated fatty acids in an organism, into which nucleic acids have been introduced, which code for polypeptides with ?-5 elongase activity. Said nucleic acid sequences, optionally with further nucleic acid sequences, coding for polypeptides for the biosynthesis of fatty acids and lipid metabolism, are advantageously expressed in the organism. Nucleic acid sequences coding for a ?-6 desaturase, a ?-5 desaturase, ?-4 desaturase and/or ?-6 elongase activity are particularly advantageous and, advantageously, said saturases and elongases are derived from Thalassiosira, Euglena or Ostreococcus. The invention further relates to a method for the production of oils and/or triacylglycerides with an increased content of long-chain, multiply-unsaturated fatty acids.Type: ApplicationFiled: July 16, 2004Publication date: June 26, 2008Applicant: BASF Plant Science GmbHInventors: Thorsten Zank, Jorg Bauer, Petra Cirpus, Amine Abbadi, Ernst Heinz, Xiao Qiu, Patricia Vrinten, Petra Sperling, Frederic Domergue, Astrid Meyer, Jelena Kirsch
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Publication number: 20060168687Abstract: The present invention relates to a process for producing polyunsaturated fatty acids in an organism by introducing nucleic acids into said organism which code for polypeptides having acyl-CoA:lysophospholipid acyltransferase activity. Advantageously, these nucleic acid sequences may, if appropriate together with further nucleic acid sequences coding for biosynthesis polypeptides of the fatty acid or lipid metabolism, be expressed in the transgenic organism. The invention furthermore relates to the nucleic acid sequences, to nucleic acid constructs comprising the nucleic acid sequences of the invention, to vectors comprising said nucleic acid sequences and/or said nucleic acid constructs and to transgenic organisms comprising the abovementioned nucleic acid sequences, nucleic acid constructs and/or vectors. A further part of the invention relates to oils, lipids and/or fatty acids produced by the process of the invention and to their use.Type: ApplicationFiled: January 29, 2004Publication date: July 27, 2006Applicant: BASF Plant Science GmbHInventors: Andreas Renz, Ernst Heinz, Amine Abbadi, Frederic Domergue, Thorsten Zank
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Publication number: 20030145350Abstract: The invention relates to DNA sequences which code for a protein having the enzymatic activity of a &bgr;-ketoacyl ACP synthase (KAS) of the enzyme complex of the fatty acid synthase (FAS). The invention also relates to transgenic plants and micro-organisms which contain nucleic acid sequences which code for proteins having the activity of a &bgr;-ketoacyl ACP ((acyl carrier protein)) synthase (KAS) of the enzyme complex of the fatty acid synthase (FAS). The invention further relates to a method for influencing the fatty acid pattern and/or for increasing the fatty acid content, especially the content of short and middle chain fatty acids, in plants, especially in seed tissues that synthesize and/or store triacylglycerols, as well as in micro-organisms, especially bacteria and algae. The inventive method comprises the expression of proteins having the activity of a KAS of the enzyme complex or the fatty acid synthase in transgenic plants or micro-organisms.Type: ApplicationFiled: July 12, 2002Publication date: July 31, 2003Inventors: Friedrich Spener, Amine Abbadi, Monika Brummel