Patents by Inventor Amir Aharoni

Amir Aharoni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220127349
    Abstract: Methods of reducing immunogenicity of an antibody are provided, as are methods of producing a second antibody from a first. Polypeptide and antibody sequences are also provided.
    Type: Application
    Filed: January 10, 2022
    Publication date: April 28, 2022
    Inventors: Tomer HERTZ, Anat BURKOVITZ, Amir AHARONI, Inga SOREANU
  • Patent number: 10308703
    Abstract: Death-domain receptor 3 (DR3) variants having increased binding affinity to TL1A, and composition comprising same, are provided. Further, methods of use of said peptides or composition, including, but not limited to treatment of autoimmune and/or inflammatory disease are provided.
    Type: Grant
    Filed: April 27, 2015
    Date of Patent: June 4, 2019
    Assignee: THE NATIONAL INSTITUTE FOR BIOTECHNOLOGY I
    Inventors: Amir Aharoni, Itay Levin
  • Patent number: 9850294
    Abstract: A protein comprising an amino acid sequence having at least 97% homology to SEQ ID NO: 1. The amino acid sequence comprises valine at position 60, glycine at position 123 and lysine at position 109 and the protein binds hIL17A.
    Type: Grant
    Filed: July 8, 2016
    Date of Patent: December 26, 2017
    Assignee: THE NATIONAL INSTITUTE FOR BIOTECHNOLOGY IN THE NEGEV, LTD.
    Inventors: Amir Aharoni, Marianna Zaretzky
  • Publication number: 20170114118
    Abstract: Death-domain receptor 3 (DR3) variants having increased binding affinity to TL1A, and composition comprising same, are provided. Further, methods of use of said peptides or composition, including, but not limited to treatment of autoimmune and/or inflammatory disease are provided.
    Type: Application
    Filed: April 27, 2015
    Publication date: April 27, 2017
    Inventors: Amir AHARONI, Itay LEVIN
  • Publication number: 20160376343
    Abstract: A protein comprising an amino acid sequence having at least 97% homology to SEQ ID NO: 1. The amino acid sequence comprises valine at position 60, glycine at position 123 and lysine at position 109 and the protein binds hIL17A.
    Type: Application
    Filed: July 8, 2016
    Publication date: December 29, 2016
    Inventors: AMIR AHARONI, MARIANNA ZARETZKY
  • Patent number: 9416168
    Abstract: Provided are engineered soluble hIL-17RA receptors with high affinity to hIL-17 that inhibit downstream IL17A induced signaling events in cells. Also provided are methods of inhibiting hIL-17A induced secretion of CXCL1 and/or IL-6 in cells, as well as methods of treating inflammation and/or inflammatory disorders in a subject.
    Type: Grant
    Filed: July 18, 2012
    Date of Patent: August 16, 2016
    Assignee: The National Institute for Biotechnology in the Negev, Ltd
    Inventors: Amir Aharoni, Marianna Zaretzky
  • Publication number: 20160053070
    Abstract: The present invention provides a composition including polyethylene and laccase wherein the laccase has an optimal specific activity at a temperature of 60° C. to 100° C. and/or in the presence of xylan. Furthermore, the invention covers a method for biodegrading/decomposing plastic by contacting laccase with an optimal specific activity at a temperature of 60° C. to 100° C. with plastic or contacting a microorganism expressing a laccase with an optimal specific activity at a temperature of 60° C. to 100° C. with plastic.
    Type: Application
    Filed: April 6, 2014
    Publication date: February 25, 2016
    Applicant: B.G NEGEV TECHNOLOGIES LTD.
    Inventors: Alex Sivan, Amir Aharoni, Or Press
  • Patent number: 9023631
    Abstract: Isolated polynucleotides and polypeptides encoded therefrom are provided. These include mutated PON enzymes with increased, modified or substantially the same substrate specificity as compared to respective wild-type PON. Also provided are kits and methods using these enzymes.
    Type: Grant
    Filed: October 21, 2013
    Date of Patent: May 5, 2015
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Dan S. Tawfik, Amir Aharoni, Leonid Gaydukov, Joel L. Sussman, Israel Silman
  • Publication number: 20150025022
    Abstract: Provided are engineered soluble hIL-17RA receptors with high affinity to hIL-17 that inhibit downstream IL17A induced signaling events in cells. Also provided are methods of inhibiting hIL-17A induced secretion of CXCL1 and/or IL-6 in cells, as well as methods of treating inflammation and/or inflammatory disorders in a subject.
    Type: Application
    Filed: July 18, 2012
    Publication date: January 22, 2015
    Inventors: Amir Aharoni, Marianna Zaretzky
  • Publication number: 20140079682
    Abstract: Isolated polynucleotides and polypeptides encoded therefrom are provided. These include mutated PON enzymes with increased, modified or substantially the same substrate specificity as compared to respective wild-type PON. Also provided are kits and methods using these enzymes.
    Type: Application
    Filed: October 21, 2013
    Publication date: March 20, 2014
    Applicant: Yeda Research and Development Co., Ltd.
    Inventors: Dan S. TAWFIK, Amir Aharoni, Leonid Gaydukov, Joel L. Sussman, Israel Silman
  • Publication number: 20110171197
    Abstract: Isolated polynucleotides and polypeptides encoded therefrom are provided. These include mutated PON enzymes with increased, modified or substantially the same substrate specificity as compared to respective wild-type PON. Also provided are kits and methods using these enzymes.
    Type: Application
    Filed: March 15, 2010
    Publication date: July 14, 2011
    Applicant: Yeda Research And Development Co. Ltd.
    Inventors: Dan S. TAWFIK, Amir Aharoni, Leonid Gaydukov, Joel L. Sussman, Israel Silman
  • Patent number: 7786071
    Abstract: Isolated polynucleotides and polypeptides encoded therefrom are provided. These include mutated PON enzymes with increased, modified or substantially the same substrate specificity as compared to respective wild-type PON. Also provided are kits and methods using these enzymes.
    Type: Grant
    Filed: March 4, 2004
    Date of Patent: August 31, 2010
    Assignee: Yeda Research And Development Co. Ltd.
    Inventors: Dan S. Tawfik, Amir Aharoni, Leonid Gaydukov, Joel L. Sussman, Israel Silman
  • Publication number: 20070077572
    Abstract: The present invention provides an in vitro system for compartmentalization of molecular or cellular libraries and provides methods for selection and isolation of desired molecules or cells from the libraries. The library includes a plurality of distinct molecules or cells encapsulated within a water-in-oil-in-water emulsion. The emulsion includes a continuous external aqueous phase and a discontinuous dispersion of water-in-oil droplets. The internal aqueous phase of a plurality of such droplets comprises a specific molecule or cell that is within the plurality of distinct molecules or cells of the library.
    Type: Application
    Filed: May 24, 2006
    Publication date: April 5, 2007
    Applicants: YEDA RESEARCH AND DEVELOPMENT CO. LTD., YISSUM RESEARCH DEVELOPMENT COMPANY THE HEBREW UNIVERSITY OF JERUSALEM, MEDICAL RESEARCH COUNCIL
    Inventors: Dan Tawfik, Kalia Bernath, Amir Aharoni, Sergio Peisajovich, Andrew Griffiths, Enrico Mastrobattista, Shlomo Magdassi
  • Publication number: 20060205933
    Abstract: Isolated polynucleotides and polypeptides encoded therefrom are provided. These include mutated PON enzymes with increased, modified or substantially the same substrate specificity as compared to respective wild-type PON. Also provided are kits and methods using these enzymes.
    Type: Application
    Filed: March 4, 2004
    Publication date: September 14, 2006
    Inventors: Dan Tawfik, Amir Aharoni, Leonid Gaydukov, Joel Sussman, Isreal Silman
  • Patent number: 6014694
    Abstract: A system for adaptively transporting video over networks wherein the available bandwidth varies with time. The system comprises a video/audio codec that functions to compress, code, decode and decompress video streams that are transmitted over networks having available bandwidths that vary with time and location. Depending on the channel bandwidth, the system adjusts the compression ratio to accommodate a plurality of bandwidths ranging from 20 Kbps for POTS to several Mbps for switched LAN and ATM environments. Bandwidth adjustability is provided by offering a trade off between video resolution, frame rate and individual frame quality. The system generates a video data stream comprised of Key, P and B frames from a raw source of video. Each frame type is further comprised of multiple levels of data representing varying degrees of quality.
    Type: Grant
    Filed: June 26, 1997
    Date of Patent: January 11, 2000
    Assignee: Citrix Systems, Inc.
    Inventors: Amir Aharoni, Stas Khirman, Eugene Taits, Oren Ariel