Patents by Inventor Amir Avdagic

Amir Avdagic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7868174
    Abstract: The present disclosure relates to an improved process for the preparation of enantiomerically enriched alcohols of Formula (I), from the corresponding ketone of Formula (II), by asymmetric transfer hydrogenation, using a hydrogen donor, catalyzed by a ruthenium or rhodium complex of an optically active N-sulfamoyl-1,2-diamine. R is as defined herein.
    Type: Grant
    Filed: July 21, 2005
    Date of Patent: January 11, 2011
    Assignee: Pliva-Istrazivanje I Razvoj d.o.o.
    Inventors: Amir Avdagic, Barbara Mohar, Damjan Sterk, Michel Stephan
  • Publication number: 20100240926
    Abstract: (R)—N-benzyl-2-(benzyloxycarbonylamino)-3-methoxypropionamide is an intermediate useful for preparing lacosamide. It can be prepared, for example, by combining (R)—N-benzyl-2-(benzyloxycarbonylamino)-3-hydroxypropionamide with dimethylsulfate, followed by mixing with an alkali or alkaline earth metal hydroxide at a temperature of about 25° C. to about ?15° C.
    Type: Application
    Filed: March 18, 2010
    Publication date: September 23, 2010
    Applicant: PLIVA HRVATSKA D.O.O.
    Inventors: Gordana VRBANEC, Miroslava HARCA, Ana SUCEC, Damir SAHNIC, Amir AVDAGIC
  • Publication number: 20100016638
    Abstract: This invention relates to methods of making O-desmethylvenlafaxine from venlafaxine. In the methods venlafaxine is contacted with a polythiolate. The polythiolate may be prepared from the corresponding polythiol in the presence of base. The present methods provide the O-desmethylvenlafaxine in good yields and high purity and are suitable for use on an industrial scale.
    Type: Application
    Filed: July 21, 2009
    Publication date: January 21, 2010
    Inventors: Zdenko Hamersak, Amir Avdagic
  • Publication number: 20080009629
    Abstract: The present disclosure relates to an improved process for the preparation of enantiomerically enriched alcohols of Formula (I), from the corresponding ketone of Formula (II), by asymmetric transfer hydrogenation, using a hydrogen donor, catalyzed by a ruthenium or rhodium complex of an optically active N-sulfamoyl-1,2-diamine. R is as defined herein.
    Type: Application
    Filed: July 21, 2005
    Publication date: January 10, 2008
    Applicant: Pliva-Istrazivanje I Razvoj d.o.o.
    Inventors: Amir Avdagic, Barbara Mohar, Damjan Sterk, Michel Stephan
  • Publication number: 20070225325
    Abstract: Differing forms of 1-(((1(R)-(3-(2-(7-chloro-2-quinolinyl)ethenyl)-phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropane acetic acid and methods for synthesizing same.
    Type: Application
    Filed: January 19, 2005
    Publication date: September 27, 2007
    Applicant: PLIVA-ISTRAZIVANJE I RAZVOJ D.O.O.
    Inventors: Ernest Mestrovic, Michaela Horvat, Maja Devcic, Amir Avdagic, Dominik Cincic, Marina Marinkovic
  • Patent number: 5733755
    Abstract: A method for manufacturing S-3-(4'-tert-butyl)-phenyl-2-methyl propylamines having the structure I ##STR1## where NR.sub.1 R.sub.
    Type: Grant
    Filed: November 5, 1996
    Date of Patent: March 31, 1998
    Assignee: Industrie Chimiche Capparo S.p.A.
    Inventors: Vitomir Sunjic, Maja Majeric, Zdenko Hamersak, Amir Avdagic