Abstract: A bone fixation device comprises a continuum morphable hollow shell structure including a proximal end and a distal end, an implantation head at the proximal end and a screw thread positioned external to the shell structure between the implantation head and a screw tip positioned at the distal end. A bone fixation system comprises a bone fixation device as described above, at least one reinforcement wire configured for insertion into the bone fixation device, and a castable filler material configured for insertion into the bone fixation device. A bone fixation method comprises fabricating a bone fixation device as described above, drilling the implantation trajectory, implanting the bone fixation device, implanting at least one reinforcement wire within the bone fixation device, and injecting the bone fixation device with a castable filler material via an aperture of the bone fixation device.

Abstract: The present invention provides methods of forming flexible implant devices and U-bridge implants that drive into curved trajectories to enhance implant fixation in bone. The curved drilling trajectories avoid regions of low bone mineral density, such that flexible implants and/or U-bridge implants driven into the curved drilling trajectories are anchored in regions of high bone mineral density to improve the stability of bone fixation. The flexible implants and U-bridge implants are suitable for several applications, including but not limited to spinal fixation, orthopedic bone fixation, and neurosurgery.