Abstract: An integrated chip packaging for a LIDAR sensor mounted to a vehicle includes a laser assembly configured to output a beam, an optical amplifier array chip configured to amplify a beam, and a transceiver chip coupled to the laser assembly and the optical amplifier array chip. The transceiver chip may be configured to emit the beam with reference to a first surface of the transceiver chip through an optical window and receive a reflected beam from a target through the optical window. The integrated chip packaging for the LIDAR sensor defines the configuration of optical components for providing a path for the optical signal to travel in and out of the LIDAR sensor and dissipating the heat generated by the optical components for improved performance.

Abstract: A LIDAR transceiver includes a source input, coherent cells, and an optical switch. The optical switch is configured to switchably couple the source input to the coherent cells. At least one of the coherent cells includes an input port, an optical antenna, and a splitter. The input port is coupled to the optical switch and the splitter is coupled between the input port and the optical antenna. The splitter is configured to split a received portion of a laser signal into a local oscillator signal and a transmit signal, where the transmit signal is emitted through the optical antenna. A reflection of the transmit signal is received through the optical antenna as a reflected signal, where the splitter is further configured to output a return signal that is a portion of the reflected signal.

Abstract: A light detection and ranging (LIDAR) sensor system mounted to a vehicle includes a first device and a second device coupled to the first device. The first device includes a laser source and one or more optical components. The first device is configured to output an optical signal associated with a local oscillator (LO) signal. The second device includes an optical amplifier array device and a transceiver device. The optical amplifier array device includes an integrated optical component and is configured to amplify the optical signal. The transceiver device is configured to transmit the amplified optical signal to an environment and receive a returned optical signal that is reflected from an object in the environment.

Abstract: The present disclosure relates to methods of treating cancer and pharmaceutical compositions for use in the treatment of cancer, including LSD1-inhibitor-resistant cancers, comprising administering to a subject an effective amount of a cell cycle inhibitor, such as a CDK4/6 inhibitor or a p21 enhancer, and an effective amount of a LSD1 inhibitor.

Abstract: A LIDAR transceiver includes a source input, coherent cells, and an optical switch. The optical switch is configured to switchably couple the source input to the coherent cells. At least one of the coherent cells includes an input port, an optical antenna, and a splitter. The input port is coupled to the optical switch and the splitter is coupled between the input port and the optical antenna. The splitter is configured to split a received portion of a laser signal into a local oscillator signal and a transmit signal, where the transmit signal is emitted through the optical antenna. A reflection of the transmit signal is received through the optical antenna as a reflected signal, where the splitter is further configured to output a return signal that is a portion of the reflected signal.

Abstract: An integrated chip packaging for a LIDAR sensor mounted to a vehicle includes a laser assembly configured to output a beam, an optical amplifier array chip configured to amplify a beam, and a transceiver chip coupled to the laser assembly and the optical amplifier array chip. The transceiver chip may be configured to emit the beam with reference to a first surface of the transceiver chip through an optical window and receive a reflected beam from a target through the optical window. The integrated chip packaging for the LIDAR sensor defines the configuration of optical components for providing a path for the optical signal to travel in and out of the LIDAR sensor and dissipating the heat generated by the optical components for improved performance.

Abstract: A modular LIDAR system comprising a seed laser configured to output a beam, a modular modulator coupled to receive the beam output the seed laser and modulate the beam to create a modulated beam, a modular amplifier coupled to receive the modulated beam from the modular modulator and generate an amplified beam, and a modular transceiver chip coupled to the modular modulator and the modular amplifier, the transceiver chip configured to emit the beam perpendicularly from a first surface of the transceiver chip through an optical window; and receive a reflected beam from a target through the optical window.

Abstract: A LIDAR transceiver includes a source input, coherent cells, and an optical switch. The optical switch is configured to switchably couple the source input to the coherent cells. At least one of the coherent cells includes an input port, an optical antenna, and a splitter. The input port is coupled to the optical switch and the splitter is coupled between the input port and the optical antenna. The splitter is configured to split a received portion of a laser signal into a local oscillator signal and a transmit signal, where the transmit signal is emitted through the optical antenna. A reflection of the transmit signal is received through the optical antenna as a reflected signal, where the splitter is further configured to output a return signal that is a portion of the reflected signal.

Abstract: A light detection and ranging (LiDAR) system includes a switchable coherent pixel array (SCPA) and a lens system. The SCPA is on a LiDAR chip and the SCPA includes coherent pixels (CPs) and the CPs are configured to emit coherent light. The lens system is posited to direct the coherent light emitted from the SCPA into an environment of light beams and the light beams are emitted at a specific angle and the specific angle is based in part on positions of the CPs on the LiDAR chip that generated the coherent light that forms the light beams.

Abstract: A LIDAR transceiver includes an input port, optical antennas, an optical switch, splitters, and mixers. The optical switch switchably couples an input port to the optical antennas. For at least one optical path from the input port to one of the optical antennas, a splitter is coupled along the optical path. The splitter splits a received portion of a laser signal into a local oscillator signal and a transmit signal and outputs a return signal that is a portion of the reflected signal. The transmit signal is emitted through the optical antenna and a reflection of the transmit signal is received through the optical antenna as a reflected signal.

Abstract: A LIDAR transceiver includes an input port, optical antennas, an optical switch, splitters, and mixers. The optical switch switchably couples an input port to the optical antennas. For at least one optical path from the input port to one of the optical antennas, a splitter is coupled along the optical path. The splitter splits a received portion of a laser signal into a local oscillator signal and a transmit signal and outputs a return signal that is a portion of the reflected signal. The transmit signal is emitted through the optical antenna and a reflection of the transmit signal is received through the optical antenna as a reflected signal.

Abstract: The present disclosure relates to methods of treating cancer and pharmaceutical compositions for use in the treatment of cancer, including LSD1-inhibitor-resistant cancers, comprising administering to a subject an effective amount of a cell cycle inhibitor, such as a CDK4/6 inhibitor or a p21 enhancer, and an effective amount of a LSD1 inhibitor.

Abstract: Methods, systems, and apparatus, including an optical receiver including an optical source, including a substrate; a laser provided on the substrate, the laser having first and second sides and outputting first light from the first side and second light from the second side, the first light output from the first side of the laser has a first power and the second light output from the second side has a second power; and a first modulator that receives the first light and a second modulator that receives the second light, such that the power of the first light at an input of the first modulator is substantially equal to the power of the second light at an input of the second modulator.

Abstract: Methods, systems, and apparatus, including an optical receiver including a laser including a gain section; and a first tunable reflector configured to output a reference signal; a first coupler formed over the substrate; a shutter variable optical attenuator formed over the substrate, the shutter variable optical attenuator including an input port configured to receive the first portion of the reference signal from the laser; and an output port configured to provide or to block, based on a control signal, the first portion of the reference signal from the laser; and a second coupler including a first port configured to receive the first portion of the reference signal from the shutter variable optical attenuator; and a second port configured to (i) provide the first portion of the reference signal from the shutter variable optical attenuator to an optical analyzer or (ii) receive a data signal from a transmitter.

Abstract: Methods, systems, and apparatus, including an optical receiver including an optical source, including a substrate; a laser provided on the substrate, the laser having first and second sides and outputting first light from the first side and second light from the second side, the first light output from the first side of the laser has a first power and the second light output from the second side has a second power; and a first modulator that receives the first light and a second modulator that receives the second light, such that the power of the first light at an input of the first modulator is substantially equal to the power of the second light at an input of the second modulator.

Abstract: Methods, systems, and apparatus, including an optical receiver including a laser including a gain section; and a first tunable reflector configured to output a reference signal; a first coupler formed over the substrate; a shutter variable optical attenuator formed over the substrate, the shutter variable optical attenuator including an input port configured to receive the first portion of the reference signal from the laser; and an output port configured to provide or to block, based on a control signal, the first portion of the reference signal from the laser; and a second coupler including a first port configured to receive the first portion of the reference signal from the shutter variable optical attenuator; and a second port configured to (i) provide the first portion of the reference signal from the shutter variable optical attenuator to an optical analyzer or (ii) receive a data signal from a transmitter.

Abstract: Methods, systems, and apparatus, including an optical receiver including a laser including a gain section; and a first tunable reflector configured to output a reference signal; a first coupler formed over the substrate; a shutter variable optical attenuator formed over the substrate, the shutter variable optical attenuator including an input port configured to receive the first portion of the reference signal from the laser; and an output port configured to provide or to block, based on a control signal, the first portion of the reference signal from the laser; and a second coupler including a first port configured to receive the first portion of the reference signal from the shutter variable optical attenuator; and a second port configured to (i) provide the first portion of the reference signal from the shutter variable optical attenuator to an optical analyzer or (ii) receive a data signal from a transmitter.

Abstract: Methods, systems, and apparatus, including an optical receiver including an optical source, including a substrate; a laser provided on the substrate, the laser having first and second sides and outputting first light from the first side and second light from the second side, the first light output from the first side of the laser has a first power and the second light output from the second side has a second power; and a first modulator that receives the first light and a second modulator that receives the second light, such that the power of the first light at an input of the first modulator is substantially equal to the power of the second light at an input of the second modulator.

Abstract: Systems and methods for chip-integrated label-free detection and absorption spectroscopy with high throughput, sensitivity, and specificity are disclosed. The invention comprises packaged chips for multiplexing photonic crystal microcavity waveguide and photonic crystal slot waveguide devices. The packaged chips comprise crossing waveguides to prevent leakage of fluids from the microfluidic channels from the trenches or voids around the light guiding waveguides. Other embodiments are described and claimed.

Abstract: Systems and methods for chip-integrated label-free detection and absorption spectroscopy with high throughput, sensitivity, and specificity are disclosed. The invention comprises packaged chips for multiplexing photonic crystal waveguide and photonic crystal slot waveguide devices. Other embodiments are described and claimed.