Abstract: A closed-system liquid transfer device is used with each of an infusion liquid container containing an infusion liquid, a medicament supply containing a medicament, and an infusion set. The closed-system liquid transfer device includes first, second, and third connectors that respectively connect and resist removal from the infusion liquid container, the infusion set, and the medicament supply.

Abstract: A liquid transfer device is described. The device comprises a connector body comprising a projection portion defining a tab and an IV port arranged at a first end of the connector body, the IV port comprising an elongate connecting member projecting therefrom and defining a cutout. The projection portion is configured to be received by the elongate connecting member, and the tab is configured to mate with the cutout so as to rotationally fix the IV port relative to the connector body.

Abstract: Liquid transfer devices with an integral telescopic vial adapter for use with an infusion liquid container and an initially non-punctured intact discrete injection vial. The integral telescopic vial adapter is configured for initial telescopic snap mounting on a discrete injection vial leaving its injection vial stopper non-punctured until a subsequent compaction for puncturing the injection vial stopper. The integral telescopic vial adapter includes a safety catch mechanism for precluding advertent compaction from a pre-compacted state to a compacted state. The integral telescopic vial adapter includes a clamping arrangement for irreversibly clamping same in its final compacted state.

Abstract: Dual vial adapter assemblages having a triple component construction as follows: a first vented female vial adapter for telescopic mounting on a drug vial, a second vented female vial adapter for telescopic mounting on a liquid vial and a tubular liquid transfer coupler for coupling the first vented female vial adapter and the second vented female vial adapter for establishing a dual sealed lumen arrangement therebetween. The dual sealed lumen arrangement includes a central sealed liquid lumen for gravitational flow of liquid contents from a liquid vial to a drug vial and a sealed air lumen radial outward from the central sealed liquid lumen for venting air displaced from the drug vial to the liquid vial for assisting the gravitational flow of liquid contents by creating a closed system between the liquid vial and the drug vial.

Abstract: A liquid transfer device is described. The device comprises a connector body comprising a projection portion defining a tab and an IV port arranged at a first end of the connector body, the IV port comprising an elongate connecting member projecting therefrom and defining a cutout. The projection portion is configured to be received by the elongate connecting member, and the tab is configured to mate with the cutout so as to rotationally fix the IV port relative to the connector body.

Abstract: A liquid transfer device is described. The liquid transfer device comprising a vial adapter comprising a puncturing cannula for puncturing an injection vial stopper, an IV spike and a substitute IV port holder for receiving a substitute IV port, and a flow control member port. The IV spike, the substitute IV port holder and the puncturing cannula are in flow communication with the flow control member port. The liquid transfer device comprising a flow control member sealingly inserted in the flow control member port. Rotation of the flow control member between a plurality of positions controls flow communication of the liquid transfer device, the positions comprising a mixing position for enabling flow communication between the IV spike and the puncturing cannula; and an administering position for enabling flow communication between the IV spike and the substitute IV port holder.

Abstract: A liquid transfer device is described. The liquid transfer device comprising a vial adapter comprising a puncturing cannula for puncturing an injection vial stopper, an IV spike and a substitute IV port holder for receiving a substitute IV port, and a flow control member port. The IV spike, the substitute IV port holder and the puncturing cannula are in flow communication with the flow control member port. The liquid transfer device comprising a flow control member sealingly inserted in the flow control member port. Rotation of the flow control member between a plurality of positions controls flow communication of the liquid transfer device, the positions comprising a mixing position for enabling flow communication between the IV spike and the puncturing cannula; and an administering position for enabling flow communication between the IV spike and the substitute IV port holder.

Abstract: Liquid transfer devices with an integral telescopic vial adapter for use with an infusion liquid container and an initially non-punctured intact discrete injection vial. The integral telescopic vial adapter is configured for initial telescopic snap mounting on a discrete injection vial leaving its injection vial stopper non-punctured until a subsequent compaction for puncturing the injection vial stopper. The integral telescopic vial adapter includes a safety catch mechanism for precluding advertent compaction from a pre-compacted state to a compacted state. The integral telescopic vial adapter includes a clamping arrangement for irreversibly clamping same in its final compacted state.

Abstract: Liquid transfer devices with an integral telescopic vial adapter for use with an infusion liquid container and an initially non-punctured intact discrete injection vial. The integral telescopic vial adapter is configured for initial telescopic snap mounting on a discrete injection vial leaving its injection vial stopper non-punctured until a subsequent compaction for puncturing the injection vial stopper. The integral telescopic vial adapter includes a safety catch mechanism for precluding advertent compaction from a pre-compacted state to a compacted state. The integral telescopic vial adapter includes a clamping arrangement for irreversibly clamping same in its final compacted state.

Abstract: Dual vial adapter assemblage for use with a drug vial and a liquid vial and including a vented drug vial adapter and a vented liquid vial adapter such that simultaneous venting of the liquid vial and the drug vial assists gravitational flow of liquid contents from the liquid vial into the drug vial for forming liquid drug therein.

Abstract: Dual vial adapter assemblages having a triple component construction as follows: a first vented female vial adapter for telescopic mounting on a drug vial, a second vented female vial adapter for telescopic mounting on a liquid vial and a tubular liquid transfer coupler for coupling the first vented female vial adapter and the second vented female vial adapter for establishing a dual sealed lumen arrangement therebetween. The dual sealed lumen arrangement includes a central sealed liquid lumen for gravitational flow of liquid contents from a liquid vial to a drug vial and a sealed air lumen radial outward from the central sealed liquid lumen for venting air displaced from the drug vial to the liquid vial for assisting the gravitational flow of liquid contents by creating a closed system between the liquid vial and the drug vial.

Abstract: Dual vial adapter assemblages including two identical twin vial adapters each having an upright vial adapter connector of a first connector type and a dual ended liquid transfer coupler interdisposed between the two identical twin vial adapters and having a pair of opposite coupler ends in the form of twin connectors of a second connector type for sealed engagement with the vial adapter connectors of the first connector type.

Abstract: Liquid transfer devices with an integral telescopic vial adapter for use with an infusion liquid container and an initially non-punctured intact discrete injection vial. The integral telescopic vial adapter is configured for initial telescopic snap mounting on a discrete injection vial leaving its injection vial stopper non-punctured until a subsequent compaction for puncturing the injection vial stopper. The integral telescopic vial adapter includes a safety catch mechanism for precluding advertent compaction from a pre-compacted state to a compacted state. The integral telescopic vial adapter includes a clamping arrangement for irreversibly clamping same in its final compacted state.

Abstract: Dual vial adapter assemblages including two identical twin vial adapters each having an upright vial adapter connector of a first connector type and a dual ended liquid transfer coupler interdisposed between the two identical twin vial adapters and having a pair of opposite coupler ends in the form of twin connectors of a second connector type for sealed engagement with the vial adapter connectors of the first connector type.

Abstract: Dual vial adapter assemblage for use with a drug vial and a liquid vial and including a vented drug vial adapter and a vented liquid vial adapter such that simultaneous venting of the liquid vial and the drug vial assists gravitational flow of liquid contents from the liquid vial into the drug vial for forming liquid drug therein.

Abstract: Medical devices including a vial adapter with an inline dry drug module for use with a vial, a needleless syringe and a carrier liquid for filling the needleless syringe with an injection solution for injection to a patient. The inline dry drug modules include a dry drug storage component for storing a dry drug dosage and a uniform carrier liquid distribution component for promoting uniform contact of the dry drug storage component by the carrier liquid to form an injection solution from the dry drug dosage. The inline dry drug modules can include a discrete dry drug storage component and a discrete uniform carrier liquid distribution component or a dual purpose component for both drug storage and uniform carrier liquid distribution. The vial adapters can be provided in vented or non-vented versions.

Abstract: An optical system and apparatus for the diagnosis of a biological sample is disclosed. An embodiment of the apparatus includes an optical probe, a probe head distally connectable to the optical probe, the optical probe further comprising at least one optical element for applying an electromagnetic radiation of a first wavelength to the biological sample, and one or more collection elements positioned proximate the at least one optical element; and an analyzer for analyzing a signal received from the biological sample by the one or more collection elements.