Abstract: A computerized method is provided for detecting whether a subject is experiencing an event (e.g., an eating event or a scratching event). The method may comprise receiving time-series data derived from data recorded by an actigraphy device worn on a wrist of the subject and computing a set of birth and death coordinates for each topological feature of a plurality of topological features in the received time-series data. The method may further comprise calculating a digital feature based on the computed set of birth and death coordinates and determining whether the subject is experiencing the event based on the calculated digital feature. In some embodiments, methods are also provided for using Bayesian methods for selecting digital features to use in detecting whether the subject is experiencing the event.