Patents by Inventor Amir ORYAN (ORIAN)

Amir ORYAN (ORIAN) has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RNF4 TARGETING COMPOUNDS AND USES THEREOF
    Publication number: 20240132486
    Abstract: The present invention provides compounds and pharmaceutical compositions comprising thereof. Further, methods for treating or preventing development of a RNF4 related disorder in a subject in need thereof are also provided.
    Type: Application
    Filed: September 21, 2023
    Publication date: April 25, 2024
    Inventors: Amir ORYAN (ORIAN), Ashraf BRIK, Yamen ABU AHMAD, Satish GANDHESIRI
  • Prognostic biomarker in cancer
    Patent number: 11407827
    Abstract: The present invention is directed to a monoclonal antibody or an antigen-binding portion thereof having specific binding affinity to RING finger protein 4 (RNF4). The invention is further directed to use of the antibody or an antigen-binding portion thereof in detecting a RNF4-associated disease in a subject, such as cancer.
    Type: Grant
    Filed: March 14, 2019
    Date of Patent: August 9, 2022
    Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
    Inventors: Amir Oryan (Orian), Yaniv Zohar, Emily Hersh-Avitan
  • A PROGNOSTIC BIOMARKER IN CANCER
    Publication number: 20210047400
    Abstract: The present invention is directed to a monoclonal antibody or an antigen-binding portion thereof having specific binding affinity to RING finger protein 4 (RNF4). The invention is further directed to use of the antibody or an antigen-binding portion thereof in detecting a RNF4-associated disease in a subject, such as cancer.
    Type: Application
    Filed: March 14, 2019
    Publication date: February 18, 2021
    Inventors: Amir ORYAN (ORIAN), Yaniv ZOHAR, Emily HERSH-AVITAN