Patents by Inventor Amir Sherman

Amir Sherman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYSTEM AND METHOD FOR ASSISTING THE POSITIONING OF MEDICAL INSTRUMENTS
    Publication number: 20140296974
    Abstract: The present invention relates to a device, system and method for assisting the positioning of medical instruments. The system comprises a hollow tubular member such as a sheath or sleeve comprising a rotational indicator element. The system further comprises an elongated rod having a blade on its distal end and comprising a rotational indicator element (aligned with the blade orientation) and a stopper close to its proximal end.
    Type: Application
    Filed: November 1, 2012
    Publication date: October 2, 2014
    Inventors: Gideon Meyer-Brodnitz, Michal Lipperman, Lior Rosen, Yaron Tal, Lea Lak, Amir Sherman
  • Combined micro-channel generation and iontophoresis for transdermal delivery of pharmaceutical agents
    Patent number: 7558625
    Abstract: The present invention relates to methods of transdermal delivery of pharmaceutical agents. In particular, the present invention relates to a method for transdermal delivery by generating micro-channels on the skin of a subject and delivering iontophoretically a pharmaceutical agent through the micro-channels. The method provides synergistic transdermal delivery of such pharmaceutical agents.
    Type: Grant
    Filed: May 17, 2007
    Date of Patent: July 7, 2009
    Assignee: TransPharma Medical Ltd.
    Inventors: Galit Levin, Amikam Gershonowitz, Meir Stern, Amir Sherman
  • Methods for improving secondary metabolite production in fungi
    Publication number: 20090075327
    Abstract: The invention relates to the production of secondary metabolites by fungi. More particularly, the invention relates to improvement of production of commercially important secondary metabolites by fungi. The invention provides methods for improving secondary metabolite production in a fungus, comprising modulating the expression of a gene involved in regulation of secondary metabolite production.
    Type: Application
    Filed: March 7, 2001
    Publication date: March 19, 2009
    Inventors: Robert Busby, Brian Cali, Peter Hecht, Doug Holtzman, Kevin Madden, Mary Maxon, Todd Milne, Thea Norman, John Royer, Sofie Salama, Amir Sherman, Jeff Silva, Eric Summers
  • COMBINED MICRO-CHANNEL GENERATION AND IONTOPHORESIS FOR TRANSDERMAL DELIVERY OF PHARMACEUTICAL AGENTS
    Publication number: 20070260170
    Abstract: The present invention relates to methods of transdermal delivery of pharmaceutical agents. In particular, the present invention relates to a method for transdermal delivery by generating micro-channels on the skin of a subject and delivering iontophoretically a pharmaceutical agent through the micro-channels. The method provides synergistic transdermal delivery of such pharmaceutical agents.
    Type: Application
    Filed: May 17, 2007
    Publication date: November 8, 2007
    Inventors: Galit Levin, Amikam Gershonowitz, Meir Stern, Amir Sherman
  • Modulation of secondary metabolite production by zinc binuclear cluster proteins
    Patent number: 7229784
    Abstract: Methods for improving the production of a secondary metabolite by a fungus by increasing the yield or productivity of the secondary metabolite produced by the fungus are described. The methods include increasing the expression of LYS14, for example, by transforming a cell with a nucleic acid molecule encoding LYS14.
    Type: Grant
    Filed: September 19, 2001
    Date of Patent: June 12, 2007
    Assignee: Microbia, Inc.
    Inventors: Douglas Holtzman, Kevin T. Madden, Mary Maxon, Amir Sherman
  • love variant regulator molecules
    Patent number: 7196189
    Abstract: The invention provides variant regulator proteins of secondary metabolite production and nucleic acids encoding said variant regulator proteins. In particular, the invention provides variant regulator molecules of the lovE protein.
    Type: Grant
    Filed: March 28, 2003
    Date of Patent: March 27, 2007
    Assignee: Microbia, Inc.
    Inventors: Shannon Roberts, Amir Sherman, Joshua Trueheart, G. Todd Milne, John C. Royer
  • lovE variant regulator molecules
    Patent number: 7026460
    Abstract: The invention provides variant regulator proteins of secondary metabolite production and nucleic acids encoding said variant regulator proteins. In particular, the invention provides variant regulator molecules of the lovE protein.
    Type: Grant
    Filed: October 9, 2001
    Date of Patent: April 11, 2006
    Assignee: Microbia, Inc.
    Inventors: Shannon Roberts, Amir Sherman, Joshua Trueheart, G. Todd Milne
  • Methods for improving secondary metabolite production in fungi
    Patent number: 6949356
    Abstract: The invention relates to the production of secondary metabolites by fungi. More particularly, the invention relates to improvement of production of commercially important secondary metabolites by fungi. The invention provides methods for improving secondary metabolite production in a fungus, comprising modulating the expression of a gene involved in regulation of secondary metabolite production.
    Type: Grant
    Filed: January 19, 2000
    Date of Patent: September 27, 2005
    Assignee: Microbia, Inc.
    Inventors: Robert Busby, Brian Cali, Peter Hecht, Doug Holtzman, Kevin Madden, Mary Maxon, Todd Milne, Thea Norman, John Royer, Sofie Salama, Amir Sherman, Jeff Silva, Eric Summers
  • Love variant regulator molecules
    Publication number: 20050118690
    Abstract: The invention provides variant regulator proteins of secondary metabolite production and nucleic acids encoding said variant regulator proteins. In particular, the invention provides variant regulator molecules of the lovE protein.
    Type: Application
    Filed: October 9, 2002
    Publication date: June 2, 2005
    Inventors: Shannon Roberts, Amir Sherman, Joshua Trueheart, G. Milne
  • Novel regulators of fungal gene expression
    Publication number: 20050095633
    Abstract: The invention relates to regulators of fungal gene expression and their use in commercial and medical applications. More particularly, the invention relates to regulators of fungal genes involved in production of enzymes, secondary metabolites and other useful products, as well as to regulators of genes involved in fungal invasion. The invention provides novel regulators of fungal gene expression, and methods for using regulator genes in commercial and medical applications.
    Type: Application
    Filed: September 28, 2004
    Publication date: May 5, 2005
    Inventors: Brian Cali, Douglas Holtzman, Jeffrey Silva, Joshua Trueheart, Lixin Zhang, Kevin Madden, G. Milne, Amir Sherman
  • Isolated nucleic acid molecule encoding a regulator of fungal gene expression
    Patent number: 6806082
    Abstract: The invention relates to regulators of fungal gene expression and their use in commercial and medical applications. More particularly, the invention relates to regulators of fungal genes involved in production of enzymes, secondary metabolites and other useful products, as well as to regulators of genes involved in fungal invasion. The invention provides novel regulators of fungal gene expression, and methods for using regulator genes in commercial and medical applications.
    Type: Grant
    Filed: December 22, 2001
    Date of Patent: October 19, 2004
    Assignee: Microbia, Inc.
    Inventors: Brian M. Cali, Douglas Holtzman, Kevin T. Madden, G. Todd Milne, Amir Sherman, Jeffrey C. Silva, Joshua Trueheart, Lixin Zhang
  • lovE variant regulator molecules
    Publication number: 20040191877
    Abstract: The invention provides variant regulator proteins of secondary metabolite production and nucleic acids encoding said variant regulator proteins. In particular, the invention provides variant regulator molecules of the lovE protein.
    Type: Application
    Filed: March 28, 2003
    Publication date: September 30, 2004
    Inventors: Shannon Roberts, Amir Sherman, Joshua Trueheart, G. Todd Milne, John C. Royer
  • Regulation of fungal gene expression
    Publication number: 20030235857
    Abstract: Disclosed herein are methods for regulating fungal gene expression, and reagents for carrying out those methods.
    Type: Application
    Filed: June 4, 2003
    Publication date: December 25, 2003
    Applicant: Whitehead Institute for BioMedical Research, a Delaware corporation
    Inventors: Steffen Rupp, Laura Robertson, Eric F. Summers, Peter Hecht, Radclyffe Roberts, Hiten Madhani, Cora Ann Styles, Hsiu-Jung Lo, Amir Sherman, Brian Cali, Gerald R. Fink
  • IovE variant regulator molecules
    Publication number: 20030143705
    Abstract: The invention provides variant regulator proteins of secondary metabolite production and nucleic acids encoding said variant regulator proteins. In particular, the invention provides variant regulator molecules of the lovE protein.
    Type: Application
    Filed: October 9, 2001
    Publication date: July 31, 2003
    Inventors: Shannon Roberts, Amir Sherman, Joshua Trueheart, G. Todd Milne
  • Regulation of fungal gene expression
    Patent number: 6599705
    Abstract: Disclosed herein are methods for regulating fungal gene expression, and reagents for carrying out those methods.
    Type: Grant
    Filed: May 22, 2001
    Date of Patent: July 29, 2003
    Assignee: The Whitehead Institute for Biomedical Research
    Inventors: Steffen Rupp, Laura Robertson, Eric F. Summers, Peter Hecht, Radclyffe Roberts, Hiten Madhani, Cora Ann Styles, Hsiu-Jung Lo, Amir Sherman, Brian Cali, Gerald R. Fink
  • Novel regulators of fungal gene expression
    Publication number: 20020182708
    Abstract: The invention relates to regulators of fungal gene expression and their use in commercial and medical applications. More particularly, the invention relates to regulators of fungal genes involved in production of enzymes, secondary metabolites and other useful products, as well as to regulators of genes involved in fungal invasion. The invention provides novel regulators of fungal gene expression, and methods for using regulator genes in commercial and medical applications.
    Type: Application
    Filed: December 22, 2001
    Publication date: December 5, 2002
    Inventors: Brian M. Cali, Douglas Holtzman, Kevin T. Madden, G. Todd Milne, Amir Sherman, Jeffrey C. Silva, Joshua Trueheart, Lixin Zhang
  • Regulation of fungal gene expression
    Publication number: 20020155517
    Abstract: Disclosed herein are methods for regulating fungal gene expression, and reagents for carrying out those methods.
    Type: Application
    Filed: May 22, 2001
    Publication date: October 24, 2002
    Inventors: Steffen Rupp, Laura Robertson, Eric F. Summers, Peter Hecht, Radclyffe Roberts, Hiten Madhani, Cora Ann Styles, Hsiu-Jung Lo, Amir Sherman, Brian Cali, Gerald R. Fink
  • Methods for improving secondary metabolite production in fungi
    Publication number: 20020128250
    Abstract: The invention relates to the production of secondary metabolites by fungi. More particularly, the invention relates to improvement of production of commercially important secondary metabolites by fungi. The invention provides methods for improving secondary metabolite production in a fungus, comprising modulating the expression of a gene involved in regulation of secondary metabolite production.
    Type: Application
    Filed: March 7, 2001
    Publication date: September 12, 2002
    Inventors: Robert Busby, Brian Cali, Peter Hecht, Doug Holtzman, Kevin Madden, Mary Maxon, Todd Milne, Thea Norman, John Royer, Sofie Salama, Amir Sherman, Jeff Silva, Eric Summers
  • Regulation of fungal gene expression
    Patent number: 6303302
    Abstract: Disclosed herein are methods for regulating fungal gene expression, and reagents for carrying out those methods.
    Type: Grant
    Filed: November 10, 1998
    Date of Patent: October 16, 2001
    Assignee: The Whitehead Institute for Biomedical Research
    Inventors: Steffen Rupp, Laura Robertson, Eric F. Summers, Peter Hecht, Radclyffe Roberts, Hiten Madhani, Cora Ann Styles, Hsiu-Jung Lo, Amir Sherman, Brian Cali, Gerald L. Fink