Abstract: Provided herein are thermal devices and single-use temperature measurement devices to predict and to monitor core body temperature in a subject, such as a patient. The devices utilize a plurality of thermal or temperature sensors disposed on a patch and insulated one from the other and a connection to a machine learning algorithm for prediction and monitoring. Also provided are systems and methods using the thermal device or temperature monitoring device and the machine learning algorithm to predict and measure core body temperature in the subject.

Abstract: Provided herein are thermal devices and single-use temperature measurement devices to predict and to monitor core body temperature in a subject, such as a patient. The devices utilize a plurality of thermal or temperature sensors disposed on a patch and insulated one from the other and a connection to a machine learning algorithm for prediction and monitoring. Also provided are systems and methods using the thermal device or temperature monitoring device and the machine learning algorithm to predict and measure core body temperature in the subject.

Abstract: Provided is a wearable fundus camera configured to be worn as a headset by a human, the wearable fundus camera comprising: an infrared light source configured to output infrared light to be directed at a retina of the human; an image sensor configured to capture infrared images depicting a retina of an eye of the human under illumination from the infrared light source without a pupil of the eye being dilated with mydriatics; and an eye cuff configured to be biased against a face of the human and occlude at least some ambient light from reaching the image sensor.

Abstract: Provided herein are medical devices, systems and platforms to monitor tissue properties such as oxygen saturation, temperature and degree of tissue edema for diagnosis and post-operative patient monitoring. The medical devices may be handheld or portable or may be removable patches. The medical devices utilize light of various visible and near-infrared wavelengths to interrogate a tissue where the intensities of reflected light correlate to one or more tissue property. Also provided are methods for measuring tissue properties, for detecting pressure ulcers and for remotely monitoring in real time a surgical flap on a post-operative subject via the medical devices.

Abstract: Provided herein are medical devices, systems and platforms to monitor tissue properties such as oxygen saturation, temperature and degree of tissue edema for diagnosis and post-operative patient monitoring. The medical devices may be handheld or portable or may be removable patches. The medical devices utilize light of various visible and near-infrared wavelengths to interrogate a tissue where the intensities of reflected light correlate to one or more tissue property. Also provided are methods for measuring tissue properties, for detecting pressure ulcers and for remotely monitoring in real time a surgical flap on a post-operative subject via the medical devices.

Abstract: Provided is a wearable fundus camera configured to be worn as a headset by a human, the wearable fundus camera comprising: an infrared light source configured to output infrared light to be directed at a retina of the human; an image sensor configured to capture infrared images depicting a retina of an eye of the human under illumination from the infrared light source without a pupil of the eye being dilated with mydriatics; and an eye cuff configured to be biased against a face of the human and occlude at least some ambient light from reaching the image sensor.

Abstract: Provided is a wearable fundus camera configured to be worn as a headset by a human, the wearable fundus camera comprising: an infrared light source configured to output infrared light to be directed at a retina of the human; an image sensor configured to capture infrared images depicting a retina of an eye of the human under illumination from the infrared light source without a pupil of the eye being dilated with mydriatics; and an eye cuff configured to be biased against a face of the human and occlude at least some ambient light from reaching the image sensor.

Abstract: Provided is a wearable fundus camera configured to be worn as a headset by a human, the wearable fundus camera comprising: an infrared light source configured to output infrared light to be directed at a retina of the human; an image sensor configured to capture infrared images depicting a retina of an eye of the human under illumination from the infrared light source without a pupil of the eye being dilated with mydriatics; and an eye cuff configured to be biased against a face of the human and occlude at least some ambient light from reaching the image sensor.

Abstract: A circuit for generating a swept source optical coherence tomography (SS-OCT) imaging calibration clock. The circuit comprises a first photodetector configured to convert an SS-OCT optical calibration signal to an SS-OCT electrical calibration signal, a first analog-to-digital converter (ADC) coupled to the first photodetector and configured to convert the SS-OCT electrical calibration signal to a sequence of SS-OCT calibration signal digital values, a processing unit coupled to the first ADC that, when initiated, is configured to demodulate the sequence of SS-OCT calibration signal digital values to obtain a sequence of SS-OCT wave number digital values, where each SS-OCT wave number digital value corresponds to one of the SS-OCT calibration signal digital values, and a level crossing sampler that is configured to track a wave number associated with the SS-OCT optical calibration signal and to generate an SS-OCT calibration clock pulse.

Abstract: A circuit for generating a swept source optical coherence tomography (SS-OCT) imaging calibration clock. The circuit comprises a first photodetector configured to convert an SS-OCT optical calibration signal to an SS-OCT electrical calibration signal, a first analog-to-digital converter (ADC) coupled to the first photodetector and configured to convert the SS-OCT electrical calibration signal to a sequence of SS-OCT calibration signal digital values, a processing unit coupled to the first ADC that, when initiated, is configured to demodulate the sequence of SS-OCT calibration signal digital values to obtain a sequence of SS-OCT wave number digital values, where each SS-OCT wave number digital value corresponds to one of the SS-OCT calibration signal digital values, and a level crossing sampler that is configured to track a wave number associated with the SS-OCT optical calibration signal and to generate an SS-OCT calibration clock pulse.