Abstract: This invention is directed to compounds of Formula (I) pharmaceutically acceptable salts, esters, and prodrugs thereof, to their preparation, to pharmaceutical compositions comprising compounds of Formula I, and to their uses as antimicrobial agents.

Abstract: Systems and methods for machine learning assisted contactless control of a physical device are disclosed. In some embodiments, a system comprises at least one processor and memory storing instructions executable by the at least one processor, the instructions when executed cause the system to obtain a plurality of images of a physical device; identify the physical device and a control panel of the physical device using the one or more images; train, using supervised learning, a plurality of machine learning control operations models of a machine learning system, to determine control operations of one or more components of the control panel; and deliver a trained control operations model of the plurality of control operations models to a user device to facilitate contactless control of the physical device by the user device.

Abstract: A method is provided to automatically perform a firmware upgrade of a wireless network. The method includes receiving by a node of the wireless network using slave-mode, a firmware upgrade request from another node of the wireless network and performing by the node a firmware upgrade using upgrade instructions included with the firmware upgrade request. The method further includes determining by the node using master mode, at least two eligible nearby nodes of the wireless network, updating the firmware upgrade request, and transmitting by the node using master mode the firmware upgrade request to the at least two eligible nearby nodes of the network.

Abstract: Methods and systems to build and utilize a search infrastructure are described. The system generates, by a first indexing subsystem, full indexes of data and sends the full indexes to a plurality of query node servers via a distribution system. The system generates, mini-indexes associated with the full indexes and sends the mini-indexes to the plurality of query node servers. The system causes the plurality of query nodes to update indexing information based on the full indexes and the mini-indexes.

Abstract: A method is provided to automatically perform a firmware upgrade of a wireless network. The method includes receiving by a node of the wireless network using slave-mode, a firmware upgrade request from another node of the wireless network and performing by the node a firmware upgrade using upgrade instructions included with the firmware upgrade request. The method further includes determining by the node using master mode, at least two eligible nearby nodes of the wireless network, updating the firmware upgrade request, and transmitting by the node using master mode the firmware upgrade request to the at least two eligible nearby nodes of the network.

Abstract: This invention is directed to compounds of Formula (I) pharmaceutically acceptable salts, esters, and prodrugs thereof, to their preparation, to pharmaceutical compositions comprising compounds of Formula I, and to their uses as antimicrobial agents.

Abstract: The invention provides novel antibacterial diamide compounds, pharmaceutical compositions comprising the compounds and methods for treating or preventing an infection in a subject using the compounds.

Abstract: The invention provides novel antibacterial diamide compounds, pharmaceutical compositions comprising the compounds and methods for treating or preventing an infection in a subject using the compounds.

Abstract: Methods and systems to build and utilize a search infrastructure are described. The system generates index information components in real-time based on a database that is time-stamped. The system updates index information at a plurality of query node servers based on the index information components. A query engine receives a search query from a client machine and identifies search results based on the query and the index information. The system communicates the search results, over the network, to the client machine.

Abstract: The invention provides novel antibacterial diamide compounds, pharmaceutical compositions comprising the compounds and methods for treating or preventing an infection in a subject using the compounds.

Abstract: Methods and systems to build and utilize a search infrastructure are described. The system generates, by a first indexing subsystem, full indexes of data and sends the full indexes to a plurality of query node servers via a distribution system. The system generates, mini-indexes associated with the full indexes and sends the mini-indexes to the plurality of query node servers. The system causes the plurality of query nodes to update indexing information based on the full indexes and the mini-indexes.

Abstract: Methods and systems to build and utilize a search infrastructure are described. The system generates index information, including document updates and indexes. The system receives event notifications as the document updates are received and accumulates the index information until published. A query engine receives a search query from a client machine and identifies search results based on the query and the index information. The system communicates the search results, over the network, to the client machine.

Abstract: Methods and systems to build and utilize a search infrastructure are described. The system generates index information components in real-time based on a database that is time-stamped. The system updates index information at a plurality of query node servers based on the index information components. A query engine receives a search query from a client machine and identifies search results based on the query and the index information. The system communicates the search results, over the network, to the client machine.

Abstract: Methods and systems to build and utilize a search infrastructure are described. The system generates index information components in real-time based on a database that is time-stamped. The system updates index information at a plurality of query node servers based on the index information components. A query engine receives a search query from a client machine and identifies search results based on the query and the index information. The system communicates the search results, over the network, to the client machine.

Abstract: Methods and systems to build and utilize a search infrastructure are described. The system generates index information, including document updates and indexes. The system receives event notifications as the document updates are received and accumulates the index information until published. A query engine receives a search query from a client machine and identifies search results based on the query and the index information. The system communicates the search results, over the network, to the client machine.

Abstract: Methods and systems to build and utilize a search infrastructure are described. The system generates index information components in real-time based on a database that is time-stamped. The system updates index information at a plurality of query node servers based on the index information components. A query engine receives a search query from a client machine and identifies search results based on the query and the index information. The system communicates the search results, over the network, to the client machine.

Abstract: A method and system to configure a profile to rank search results are provided. A profile that includes behavior information organized as a plurality of components is generated. Additional behavior information is received from a user. At least one component of the plurality of components is updated using the additional behavior information received from the user. A search query is received and search results are generated based on the search query. Search results are ranked based on the updated profile.

Abstract: A method for identifying a brand name is described herein. The method involves obtaining category keywords associated with a category, designating a subgroup of the category keywords as brand name keywords for a particular brand name, receiving a search term, determining that the search term is a brand name keyword, and identifying the particular brand name corresponding to the brand name keyword.

Abstract: Methods and systems are directed toward associating, displaying, and managing notes or other annotations with emails, instant messages, or other messages. A user interface provides a listing of message headers. Selecting an annotation area associated with a message header causes an editor to open, and allows a user to enter an annotation, such as a text note, a URL, and/or other data. An annotation fragment, such as a snippet of text, is generated from the annotation and associated with the annotation and message. The annotation, the annotation fragment, an icon or another representation remains perceptibly associated with the corresponding message header whenever the message header is moved in the user interface. Placing a cursor over, or selecting the annotation representation causes the full annotation to be accessed and displayed. Clicking on, or otherwise selecting the annotation representation opens the editor to revise the full annotation.