Abstract: Embodiments of photoactivatable, lipid-based nanoparticles are disclosed, as well as methods of making and using the nanoparticles. Pharmaceutical compositions including the nanoparticles also are disclosed. The lipid-based nanoparticles include a vesicle wall surrounding a cavity, wherein the vesicle wall includes (i) a lipid bilayer comprising 1,2-bis(tricosa-10,12-diynoyl)-sn-glycero-3-phosphocholine (DC8,9PC), dipalmitoylphosphatidylcholine (DPPC), and (ii) 2-[1-hexyloxyethyl]-2-devinyl pyropheophorbide-a (HPPH) within the lipid bilayer. The nanoparticles may further include an agent within the cavity.

Abstract: Novel tools and techniques that can be used to enhance the effectiveness of photogrammetric tools, such as bundle adjustment. One set of techniques can include a photo-observable backsight operation, in which a position of target point can be observed non-photographically, and this observed position can be used to constrain a pixel coordinate location of the same target point in a bundle adjustment operation. Using another technique, a photo-observable check shot operation, the observed position of another target point can be used to verify the validity of a bundle adjustment calculation. Such techniques can be used together or separately.

Abstract: A low power keyword based speech recognition hardware architecture for hands free wake up of devices is provided. This system can be used in always ON domain for detection of voice activity, due to its low power operational ability. The system goes into deep low power state by deactivating all the non-required processes, if no activity is detected for a pre-specified time. Upon detection of the valid voice activity the system searches for the detection of the spoken keyword, if the valid keyword is detected, all the application processes are activated and system goes into full functional mode and if the voice activity doesn't contain the valid keyword present in the database then the system goes back into the deep low power state.

Abstract: An apparatus for use in image processing is set forth that comprises a pixel processor, context memory, and a context memory controller. The pixel processor is adapted to execute a pixel processing operation on a target pixel using a context of the target pixel. The context memory is adapted to store context values associated with the target pixel. The context memory controller may be adapted to control communication of context values between the pixel processor and the context memory. Further, the context memory controller may be responsive to a context initialization signal or the like provided by the pixel processor to initialize the content of the context memory to a known state, even before the pixel processor has completed its image processing operations and/or immediately after completion of its image processing operations. In one embodiment, the pixel processor executes a JBIG coding operation on the target pixel.

Abstract: An apparatus for use in image processing is set forth that comprises a pixel processor, context memory, and a context memory controller. The pixel processor is adapted to execute a pixel processing operation on a target pixel using a context of the target pixel. The context memory is adapted to store context values associated with the target pixel. The context memory controller may be adapted to control communication of context values between the pixel processor and the context memory. Further, the context memory controller may be responsive to a context initialization signal or the like provided by the pixel processor to initialize the content of the context memory to a known state, even before the pixel processor has completed its image processing operations and/or immediately after completion of its image processing operations. In one embodiment, the pixel processor executes a JBIG coding operation on the target pixel.

Abstract: An apparatus for use in image processing is set forth that comprises a pixel processor, context memory, and a context memory controller. The pixel processor is adapted to execute a pixel processing operation on a target pixel using a context of the target pixel. The context memory is adapted to store context values associated with the target pixel. The context memory controller may be adapted to control communication of context values between the pixel processor and the context memory. Further, the context memory controller may be responsive to a context initialization signal or the like provided by the pixel processor to initialize the content of the context memory to a known state, even before the pixel processor has completed its image processing operations and/or immediately after completion of its image processing operations. In one embodiment, the pixel processor executes a JBIG coding operation on the target pixel.

Abstract: An apparatus for use in image processing is set forth that comprises a pixel processor, context memory, and a context memory controller. The pixel processor is adapted to execute a pixel processing operation on a target pixel using a context of the target pixel. The context memory is adapted to store context values associated with the target pixel. The context memory controller may be adapted to control communication of context values between the pixel processor and the context memory. Further, the context memory controller may be responsive to a context initialization signal or the like provided by the pixel processor to initialize the content of the context memory to a known state, even before the pixel processor has completed its image processing operations and/or immediately after completion of its image processing operations. In one embodiment, the pixel processor executes a JBIG coding operation on the target pixel.

Abstract: A method and system for non-contact fluorescent optical tomography using patterned illumination is disclosed. The method comprises illuminating a surface of a medium with light from at least one excitation light source to project at least two patterns. Each pattern comprises at least one motif, wherein the medium comprises at least one fluorescent target. The method further comprises for each pattern, measuring excitation light reflected from the medium to generate an excitation data set. In addition, the method comprises, for each pattern, measuring fluorescence emitted from the at least one fluorescent target to generate a fluorescence data set. The method also comprises generating a 3D image of the at least one fluorescent target in the medium by applying iterative algorithm. The iterative algorithm minimizes the difference between a predicted data set based on a mathematical model, and each excitation data set and each fluorescence data set.

Abstract: A particle and a method of manufacturing a particle that includes a complex, a paramagnetic entity, and a silica layer that encapsulates the paramagnetic entity and the complex. The dielectric layer of the particle encapsulates the complex and the paramagnetic entity such that at least a portion of an outer surface of the complex is covered by the paramagnetic entity. In addition, the particle may or may not include a fluorescent entity encapsulated within the dielectric layer. Also, the particle may or may not include a targeting entity covalently bonded to the silica layer.

Abstract: A controller for use in managing an operational lifetime of at least one wind turbine is communicatively coupled to at least one wind turbine and a server sub-system. The controller is configured to receive operational data from the wind turbine, transmit the operational data to the server sub-system, and transmit a request for historical data corresponding to the wind turbine to the server sub-system. The controller is further configured to receive a response from the server sub-system, wherein the response includes historical data corresponding to the wind turbine, and to determine an estimate of a time failure of the wind turbine based on at least one of the operational data and the historical data.

Abstract: A controller for use in managing an operational lifetime of at least one wind turbine is communicatively coupled to at least one wind turbine and a server sub-system. The controller is configured to receive operational data from the wind turbine, transmit the operational data to the server sub-system, and transmit a request for historical data corresponding to the wind turbine to the server sub-system. The controller is further configured to receive a response from the server sub-system, wherein the response includes historical data corresponding to the wind turbine, and to determine an estimate of a time failure of the wind turbine based on at least one of the operational data and the historical data.

Abstract: An innovative security solution which separates a client into a Protected Context, which is the real files and resources of the client, and an Isolated Context, which is a restricted execution environment which makes use of virtualized resources to execute applications and modify content in the Isolated Context, without allowing explicit access to the resources in the Protected Context. The solution further consolidates user interfaces to allow users to seamlessly work with content in both contexts, and provide a visual indication of which display windows are rendered from content executed in the Isolated Context.

Abstract: A method and system for non-contact fluorescent optical tomography using patterned illumination is disclosed. The method comprises illuminating a surface of a medium with light from at least one excitation light source to project at least two patterns. Each pattern comprises at least one motif, wherein the medium comprises at least one fluorescent target. The method further comprises for each pattern, measuring excitation light reflected from the medium to generate an excitation data set. In addition, the method comprises, for each pattern, measuring fluorescence emitted from the at least one fluorescent target to generate a fluorescence data set. The method also comprises generating a 3D image of the at least one fluorescent target in the medium by applying iterative algorithm. The iterative algorithm minimizes the difference between a predicted data set based on a mathematical model, and each excitation data set and each fluorescence data set.

Abstract: An innovative security solution which separates a client into a Protected Context, which is the real files and resources of the client, and an Isolated Context, which is a restricted execution environment which makes use of virtualized resources to execute applications and modify content in the Isolated Context, without allowing explicit access to the resources in the Protected Context. The solution further consolidates user interfaces to allow users to seamlessly work with content in both contexts, and provide a visual indication of which display windows are rendered from content executed in the Isolated Context.