Abstract: A medical imaging system for processing an original medical image is provided. The system includes a seed generator for receiving the original medical image representing an original blood vessel and to generate coarse seeds on a basis of vesselness feature in respect to every pixel of the original blood vessel represented by the medical image, and a seed processor for receiving the coarse seeds and for processing the coarse seeds to select a set of refined seeds on a basis of the regression profile for each of the coarse seed by using random forest classification, such that the set of refined seeds are selected from the coarse seeds such that the set of refined seeds adapted to lie on a corrected blood vessel.

Abstract: A medical imaging system for processing an original medical image is provided. The system includes a seed generator for receiving the original medical image representing an original blood vessel and to generate coarse seeds on a basis of vesselness feature in respect to every pixel of the original blood vessel represented by the medical image, and a seed processor for receiving the coarse seeds and for processing the coarse seeds to select a set of refined seeds on a basis of the regression profile for each of the coarse seed by using random forest classification, such that the set of refined seeds are selected from the coarse seeds such that the set of refined seeds adapted to lie on a corrected blood vessel.

Abstract: A medical imaging system to segment an original blood vessel of a body part represented by an original medical image is provided. The system includes an image analyzer for receiving and the original medical image to analyze the original medical image to provide a Hessian Eigen analysis comprising a first data and a second data mapped to each pixel of the medical image, and an image identifier for receiving the Hessian Eigen analysis and for identifying seed points from the pixels by processing the first data and the second data along with a vesselness property, wherein the seed points are used for segmenting the original blood vessel to provide a corrected medical image representing a corrected blood vessel.

Abstract: A system and a method of analyzing an electrophysiological signal, wherein the system comprises an acquisition device for acquiring a test electrophysiological signal associated with an anatomical part of a patient and a processor configured to divide a cycle of the test electrophysiological signal into test time windows, compare a test signal value of each of the test time windows with a reference signal value of reference time windows of the reference segments of respective representations representing respective predetermined morphological classes to obtain a difference, define grid points associated with respective test time windows, respective reference time windows and respective differences, obtain a warping path using the grid points non-linearly in a predetermined order, sum differences along the grid points of each of the warping paths to obtain a cumulative distance for each of the warping paths, and classify the test electrophysiological signal into one of the respective predetermined morphologica

Abstract: The present invention relates to a system and a method for processing an initial image of coronary arteries. In accordance with the proposed method, a healthy region and a stenosed region of said arteries are first demarcated in the initial image. A first intermediate image is obtained by generating a contour of said healthy region of said arteries by segmentation of said healthy region using a level set function. A second intermediate image obtained by performing edge detection on said stenosed region. The first and second intermediate images are then combined to obtain a composite image of a single connected component represented by a plane curve on said composite image.

Abstract: Nanoparticles containing nucleic acid and suitable for use as in vivo delivery agents for nucleic acids are provided. The nanoparticles use a covalent conjugate of a polycation such as polyethylenimine and phospholipids. The final DNA-containing nanoparticle has a vesicular structure with a polyplex core surrounded by a mixed lipid/PEG-lipid monolayer envelope and offers simple preparation, high loading capacity, and in vivo stability. The nanoparticles have good in vivo stability and a prolonged blood circulation time and can effectively deliver a gene to a biological target such as a tumor.

Abstract: The present invention relates to a system and a method for processing an initial image of coronary arteries. In accordance with the proposed method, a healthy region and a stenosed region of said arteries are first demarcated in the initial image. A first intermediate image is obtained by generating a contour of said healthy region of said arteries by segmentation of said healthy region using a level set function. A second intermediate image obtained by performing edge detection on said stenosed region. The first and second intermediate images are then combined to obtain a composite image of a single connected component represented by a plane curve on said composite image.

Abstract: A condition-dependent, multiple target delivery system providing multifunctional, stimuli-sensitive pharmaceutical carriers is disclosed. The delivery system simultaneously carries on its surface various active moieties. The system is multifunctional and possesses the ability to switch on and switch off certain functions when necessary, for example, under the action of local stimuli characteristic of the target pathological zone (e.g., increased temperature or lowered pH values, which are characteristic of inflamed, ischemic and neoplastic tissues).