Patents by Inventor Amit Kumar Mandal

Amit Kumar Mandal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparation of eribulin and intermediates thereof
    Patent number: 11059799
    Abstract: The present application relate to a process for preparation of 4-Methylene tetrahydrofuran compound of formula II, which is useful as an intermediate for the preparation of halichondrin B analogues such as Eribulin.
    Type: Grant
    Filed: May 25, 2017
    Date of Patent: July 13, 2021
    Assignee: DR. REDDY'S LABORATORIES LIMITED.
    Inventors: Sudhir Sai, Debjit Basu, Kumar Sarvesh, Uday Kumar Neelam, Amit Kumar Mandal, Rakeshwar Bandichhor, Vilas Hareshwar Dahanukar
  • PROCESS FOR PREPARATION OF ERIBULIN AND INTERMEDIATES THEREOF
    Publication number: 20190276470
    Abstract: The present application relate to process for preparation of tetrahydrofuran compound of formula II, 4-Methylene tetrahydrofuran compound of formula V and tetrahydropyran compound of formula IX which are useful as intermediates for the preparation of halichondrin B analogues such as Eribulin or its pharmaceutically acceptable salts.
    Type: Application
    Filed: November 23, 2017
    Publication date: September 12, 2019
    Inventors: Michael Charles LLOYD, Pallavi RAO, Vishnu Vardhana Vema Reddy EDA, Srinivas ORUGANTI, Kumar SARVESH, Debjit BASU, Raja gopal PENUMANDLA, Prapulla Kumar PALVAI, Amit Kumar MANDAL, Vilas Hareshwar DAHANUKAR, Graham Andrew MEEK, Sarah Ann WARREN, Martin Edward FOX, Robert Wen Ming DAVIDSON
  • PROCESS FOR PREPARATION OF ERIBULIN AND INTERMEDIATES THEREOF
    Publication number: 20190177291
    Abstract: The present application relate to a process for preparation of 4-Methylene tetrahydrofuran compound of formula II, which is useful as an intermediate for the preparation of halichondrin B analogues such as Eribulin.
    Type: Application
    Filed: May 25, 2017
    Publication date: June 13, 2019
    Inventors: Sudhir Sai, Debjit Basu, Kumar Sarvesh, Uday Kumar Neelam, Amit Kumar Mandal, Rakeshwar Bandichhor, Vilas Hareshwar Dahanukar
  • Low cost electrochemical disposable sensor for measuring glycated hemoglobin
    Patent number: 8702931
    Abstract: Design of a disposable screen printed electrode (SPE) for sensing percentage glycated hemoglobin using electrochemistry is disclosed. SPE has four electrodes, one working electrode for the detection of glycated hemoglobin, one working electrode for the detection of hemoglobin and the other two electrodes are counter and reference electrodes that are common for both detection schemes. It also has a cellulose acetate membrane with lysis agents and surfactant embedded in it. Lysis agents lyse erythrocytes and release hemoglobin. Surfactants modify hemoglobin structure and enhance the rate the electron transfer and thereby the output signal during the electrochemical analysis. The SPE is low cost and user friendly. The only input from the user is a drop of blood.
    Type: Grant
    Filed: April 18, 2012
    Date of Patent: April 22, 2014
    Assignee: Indian Institute of Science
    Inventors: Siva Rama Krishna Vanjari, Navakanta Bhat, Sampath Srinivasan, Bharadwaj Amrutur, Chakrapani Kalapu, Amit Kumar Mandal
  • LOW COST ELECTROCHEMICAL DISPOSABLE SENSOR FOR MEASURING GLYCATED HEMOGLOBIN
    Publication number: 20120261257
    Abstract: Design of a disposable screen printed electrode (SPE) for sensing percentage glycated hemoglobin using electrochemistry is disclosed. SPE has four electrodes, one working electrode for the detection of glycated hemoglobin, one working electrode for the detection of hemoglobin and the other two electrodes are counter and reference electrodes that are common for both detection schemes. It also has a cellulose acetate membrane with lysis agents and surfactant embedded in it. Lysis agents lyse erythrocytes and release hemoglobin. Surfactants modify hemoglobin structure and enhance the rate the electron transfer and thereby the output signal during the electrochemical analysis. The SPE is low cost and user friendly. The only input from the user is a drop of blood.
    Type: Application
    Filed: April 18, 2012
    Publication date: October 18, 2012
    Applicant: INDIAN INSTITUTE OF SCIENCE
    Inventors: Siva Rama Krishna Vanjari, Navakanta Bhat, Sampath Srinivasan, Bharadwaj Amrutur, Chakrapani Kalapu, Amit Kumar Mandal